A Model System for Understanding Host-Pathogen Relationships Through In Vitro Host Mimicry

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dc.authoridFidanoğlu, Baran Taylan / 0009-0002-9005-8179
dc.authoridÖzkılınç, Hilal / 0000-0003-0791-975X
dc.authoridKeresteci, Nadir / 0009-0001-5828-1912
dc.contributor.authorFidanoğlu, Baran Taylan
dc.contributor.authorKeresteci, Nadir
dc.contributor.authorÖzkılınç, Hilal
dc.date.accessioned2025-05-29T02:58:05Z
dc.date.available2025-05-29T02:58:05Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIn vitro host mimicry provides a method to study host-pathogen interactions without constraints of time, space, or host presence. Monilinia fructicola and M. laxa, pathogens causing brown rot disease, have a narrow host range including some pome and stone fruits. Building on previous in vitro mimicry of the peach host and M. fructicola, this paper confirms that various hosts of both fungal species can be mimicked in vitro, offering insights into host preferences. This study developed mimic media for peach, plum, cherry, and apple hosts, evaluating pathogen preferences based on mycelial growth and the expression levels of two effector genes: cutinase 1 (CUT1) and polygalacturonase 1 (PG1). Isolates with different virulence levels were used to assess aggressiveness effects. Effector genes were significantly expressed in host-mimicking media compared to standard potato dextrose agar. Moreover, host preference with the virulence level. The high-virulent M. fructicola isolates favored peach-based medium, while low-virulent isolates preferred plum-based medium. All M. laxa isolates showed the highest growth on peach-based media and the slowest on cherry-based media. This study showed Monilinia host-pathogen relationships in vitro, and the research approach can be used as a model for necrotrophic fungal pathosystems.
dc.description.sponsorshipScientific and Technological Research Council of Turkiye (TUBITAK); TUBITAK (Scientific and Technological Research Council of Turkiye) [123Z611]
dc.description.sponsorshipOpen access funding provided by the Scientific and Technological Research Council of Turkiye (TUBITAK). This study was supported by TUBITAK (Scientific and Technological Research Council of Turkiye) Project No: 123Z611 granted to Assoc. Prof. Dr. Hilal Ozkilinc.
dc.identifier.doi10.1007/s10658-025-03030-3
dc.identifier.issn0929-1873
dc.identifier.issn1573-8469
dc.identifier.scopus2-s2.0-105002168441
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1007/s10658-025-03030-3
dc.identifier.urihttps://hdl.handle.net/20.500.12428/30273
dc.identifier.wosWOS:001461765800001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofEuropean Journal of Plant Pathology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250529
dc.subjectMonilinia spp.
dc.subjectHost mimicry
dc.subjectEffector genes
dc.subjectHost preference
dc.titleA Model System for Understanding Host-Pathogen Relationships Through In Vitro Host Mimicry
dc.typeArticle

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