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Öğe Principles of environmentally sustainable agriculture for building resilient and resource-efficient food systems(Tubitak Scientific & Technological Research Council Turkey, 2025) Cakmakci, Ramazan; Cakmakci, Songul; Cakmakci, Muhammet FatihAs the demand for greater quantities of higher-quality food grows with population expansion, climate change, urbanization, and unsustainable agricultural practices accelerate the loss of arable land, ultimately threatening agricultural sustainability. Population growth necessitates a transition to nutritious, safe, and healthy food production systems that ensure higher yields, less reduced waste, improved social outcomes, and the integration of economic, social, and environmental sustainability principles. Urgent global challenges such as resource depletion, biodiversity loss, and climate change necessitate the protection of ecosystems and the sustainable use of natural resources. Agricultural systems must enhance food production and supply productivity, strengthen system resilience, and improve resource efficiency and sustainability. The sustainable development of agricultural systems based on resilience and productivity is important to ensure food security. The aim of this review is to compile, describe, and propose future strategies for promising food systems-including transformative innovations and alternative farming techniques-to facilitate the transition toward resilient, resource-efficient, and sustainable agriculture, and to mitigate long-term challenges. It also provides recommendations for future research, sustainability, resilience, and emerging food trends aimed at promoting sustainable food systems and green technologies, protecting ecosystems, resources, and biodiversity, and optimizing waste management and natural resource use. This article focuses on future sustainable food production and security, environmental protection, alternative protein sources, and innovative agricultural techniques; it highlights scientific and technological advancements, emerging research directions, and offers a comprehensive perspective on resilient, resource-efficient, and sustainable food production systems.Öğe A disposable biosensing system for analysis of CA125 in real human serum samples(Tubitak Scientific & Technological Research Council Turkey, 2025) Afşar, Meltem; Vural, Berfin; Bilgi Kamaç, Melike; Sezgintürk, Mustafa KemalSeveral biomarkers have been developed to track the development of ovarian cancer and identify the illness at an early stage. A promising development for ovarian cancer is using cancer antigen 125 (CA125). The objective of this work is to identify the CA125 marker by utilizing an indium tin oxide polyethylene electrode. The advantage of the designed biosensor is that it is very cheap, disposable, practical, and easy to use. The necessary parameters for the developed biosensor have been optimized in detail. Repeatability, reproducibility, regeneration, storage, and selectivity studies have been completed to characterize the proposed biosensor. Electrochemical impedance spectroscopy and cyclic voltammetry techniques were used for all experimental investigations of the proposed biosensor. The immunosensor offers a large linear detection range (0.01-100 pg/mL). Moreover, this developed sensor has a 0.018 pg/mL limit of detection and a 0.06 pg/mL limit of quantification. The high accuracy of this biosensor was observed in five commercial human serums.Öğe Integrated geochemical, geoelectrical, and UAV-based methods for analyzing the Gzeylülaı landslide Çnkae(aakl, Tükyeri)(Tubitak Scientific & Technological Research Council Turkey, 2025) Erenoglu, Oya; Ulugergerli, Emin; Erenoglu, R. Cueneyt; Akbas, Abdullah; Erginal, A. EvrenThe number of reactivations increased in the G & uuml;zelyal & imath;-Erenk & ouml;y landslide area after 2013 in & Ccedil;anakkale, T & uuml;rkiye, where historical landslide activity has been recorded since 1875. This area is home to numerous summer residences and experiences ongoing slow-moving landslide activity along a 400-m-long slope, extending from the heavily trafficked & Ccedil;anakkale-& Idot;zmir highway to the coastline. In this study, the nature of the reactivations was evaluated by considering the conditioning and triggering factors that contributed to the landslide. The evaluation was based on geochemical analyses, field observations, geoelectric measurements, and unmanned aerial vehicle (UAV) data. The results revealed that the sliding occurred along a moist slip surface, rich in various clay minerals such as illite, montmorillonite, and vermiculite, at a depth of approximately 4.5 m, as determined by ERT (Electrical Resistivity Tomography). Vertical movements within the landslide area, including rises and subsidences, accounted for changes of up to 0.1 m between 2013 and 2023. Chemical Index of Weathering (CIW), Chemical Index of Alteration (CIA), and Plagioclase Index of Alteration (PIA) calculations obtained from the X-ray fluorescence (XRF) spectroscopy analysis indicate that the sliding surface is subjected to strong weathering, and these values are compatible with the X-Ray diffraction (XRD) data.Öğe Clinically significant residual stones after retrograde intrarenal surgery: Early results of a 5-year follow-up, RIRSearch group study(Elsevier, 2025) Yazici, C. M.; Sahin, M. F.; Teke, K.; Simseko, M. F.; Basatac, C.; Tuna, M. B.; Cakir, H.[No abstract available]Öğe Comparison of two different medication strategies before retrograde intrarenal surgery in patients using anticoagulant or antiplatelet agents: Results of the RIRSearch study group(Elsevier, 2025) Simsekoglu, M. E.; Ozman, O.; Cakir, H.; Teke, K.; Cinar, O.; Akgul, M.; Tuna, B.[No abstract available]Öğe Vaccine hesitancy in Türkiye: A natural language processing study on social media(Tubitak Scientific & Technological Research Council Turkey, 2025) Sari, Semih; Bayram, UlyaVaccine hesitancy is a significant public healthcare problem that is threatening everyone worldwide. Vaccine hesitancy has become more ingrained in Turkish society, mainly through social media. Unfortunately, reflections of this hesitancy are preventable deaths or permanent disabilities. Because of the uncontrolled spread of misinformation and disinformation on social media, T & uuml;rkiye is facing a future health crisis. As a step towards preventing this crisis, our main objective is to use the power of artificial intelligence techniques on Turkish social media posts to detect antivaccine posts. Through this study, it will be possible to raise awareness about the importance of vaccines in Turkish society, strengthen T & uuml;rkiye's defense mechanism against potential epidemics, and ensure that our society exchanges information in a healthier digital environment. We collected and cleaned a novel Turkish social media dataset, resulting in 3778 posts. Then, we used a baseline machine learning method, logistic regression, popular machine learning methods, support vector machines, and XGBoost to detect antivaccine thoughts and misleading information from Turkish social media posts. Further, we included transformers that changed the natural language processing domain. Evaluations are conducted using a multilingual BERT and two models specifically trained for recognizing Turkish texts, such as BERTurk. Results showed that transformers can separate Turkish social media posts with antivaccine beliefs from other posts with a 75.9% Area Under the ROC curve rate.Öğe Formation of Holocene paleosols in a relict sand dune sequence at Kıyıköy, Türkiye(Tubitak Scientific & Technological Research Council Turkey, 2025) Erginal, Ahmet Evren; Bozcu, Mustafa; Yakupoglu, Nurettin; Akbas, Abdullah; Kaya, Hakan; Tunc, Ismail OnurThe paleoclimatic indicators from a relict dune and paleosol sequence observed south of K & imath;y & imath;k & ouml;y Port, NW T & uuml;rkiye, provide insights into the variable paleoclimatic conditions in the western Black Sea coastal zone over the last 4700 yrs BP. The relict dunepaleosol sequence consists of reddish-brown coarse sands with abundant shells and overlying paleosol. Radiocarbon dating of Donax trunculus shells collected from the lowest part of the relict dune revealed the onset of sand deposition 4689 +/- 123 yrs ago. The dark-colored paleosol layer, with an Rb/Sr ratio of 0.008, yielded an age of 287 +/- 32 yrs cal BP. These findings indicate that the paleosol developed around the 1700s, during one of the coldest phases of the Little Ice Age. This layer is followed by a brown-colored buried soil, indicating a short-lived humid and rainy period, as evidenced by an Rb/Sr ratio of 0.42.Öğe Effect of preoperative urine culture timing on postoperative outcomes of retrograde intrarenal surgery: Preliminary results of the RIRSearch study(Elsevier, 2025) Yazici, C. M.; Sahin, M. F.; Teke, K.; Simseko, M. F.; Tuna, M. B.; Basatac, C.; Cinar, O.[No abstract available]Öğe Safety and efficacy of cladribine in patients discontinuing fingolimod due to elevated liver enzymes: FinClad study(Wiley, 2025) Sonmez, M.; Yetkin, M.; Mehdiyev, D. Arslan; Koseoglu, M.; Mungan, S.; Kale, N.; Terzi, M.[No abstract available]Öğe The Quaternary fluvial-lacustrine system in the Akarçay Basin (SW Anatolia): depositional environments and paleoclimatic interpretation(Tubitak Scientific & Technological Research Council Turkey, 2025) Akturk, Koray; Kapan, SevincThe Akar & ccedil;ay Closed Basin, located in southwest Anatolia, contains deformed formations and the drying Ak & scedil;ehir and Eber lakes. This study aimed to interpret the paleoenvironmental and paleoclimatic conditions of the Ak & scedil;ehir and Eber lakes, which are reported to have been connected during the Pleistocene. Based on sedimentological and mineralogical data, three different depositional subenvironments were defined, corresponding to the formation and development stages of the lake. Sedimentary facies analysis of the Pleistocene deposits in the basin revealed the following facies associations, listed from bottom to top: 1) an alluvial fan and fluvial facies association, representing the formation stage of the lake, which developed due to tectonic activity and a humid/wet climate; 2) a lakeshore facies association, corresponding to the expansion stage when the lake spread shallowly, and 3) a lake center facies association, corresponding to the closing stage when the lake began to dry, characterized by limited levels of clastic deposition under very shallow lake conditions. In the lakeshore and lake center facies association, Valvata piscinalis, Dreissena iconica and D. polymorpha species living in shallow waters and streams, as well as Laevicaspia caspia species living in mesohaline environments were identified. X-ray diffraction analysis was performed on the levels that best represented the facies associations in the basin, revealing that the dominant clay minerals in the sequence were illite and kaolinite. Combined evaluation of the sedimentological, mineralogical, and paleontological data suggests that the abundance of Valvata piscinalis and Dreissena iconica-both stream-dwelling species-at levels with increased kaolinite content indicates rainy and humid climatic periods when stream-fed conditions prevailed in the basin. Conversely, the dominance of Laevicaspia caspia and the intervals marked by illite deposition indicate cold and arid climatic periods.Öğe Unlocking PD-1/PD-L1 axis in non-small cell lung cancer: in silico design of tetrahydroquinoline-based small-molecule immune checkpoint inhibitors(Wiley, 2025) Isin, B.; Sehitoglu, M. H.; Kilinc, N.; Kazancioglu, M. Z.; Kazancioglu, E. A.[No abstract available]Öğe The Impact of Lipomastia on Self-Esteem and Social Anxiety in Adolescents with Obesity(Canadian Acad Child & Adolescent Psychiatry, 2025) Kara, Ozlem; Kaymaz, Nazan; Sirin, Hande; Uzun, Mehmet ErdemBackground: Obesity can negatively impact adolescents' self-esteem, and lipomastia can further complicate the situation. Objective: The current study endeavors to examine the influence of lipomastia on the levels of social anxiety and self-esteem in individuals with obesity. Methods: Seventy adolescent male outpatients with obesity completed a form of demographics, the SAS-A (Social Anxiety Scale for Adolescents), and the Rosenberg Self-Esteem Scale (RSES-10 item). Participants were stratified according to the presence of lipomastia, and correlation analyses were conducted to investigate the association between social anxiety and self-esteem in relation to lipomastia. Results: No significant difference was found between the lipomastia and non-lipomastia groups regarding self-esteem. While the lipomastia group had slightly higher overall social anxiety scores, significant differences were noted only in fear of negative evaluation. There was no relationship between the SAS-A total score and anthropometric measurements in both groups. However, a negative relationship was observed between self-esteem and anthropometric measurements in the lipomastia group, whereas such a relationship was not observed in the control group. Conclusion: Adolescents with lipomastia showed higher social anxiety, particularly fear of negative evaluation, despite similar demographic and anthropometric characteristics to their peers. Higher BMI correlated with lower self-esteem, highlighting the complex interplay between body image, self-esteem, and social anxiety. These findings underscore the need for targeted interventions to support adolescents with obesity and lipomastia.Öğe Multi-Criteria Evaluation of Robotic Process Automation Projects Using Proportional Spherical Fuzzy AHP & TOPSIS Methodology(Old City Publishing Inc, 2026) Dogan, Onur; Cinar, Ulas; Alkan, Nursah; Gulbay, Murat; Kahrama, CengizRobotic process automation (RPA) is a core software technology for automating digital tasks quickly and reliably and for enabling enterprise automation to execute business processes with speed and accuracy. Evaluation of RPA technologies is a muti-criteria decision making (MCDM) problem including many intangible criteria whose values are generally vague and imprecise. Spherical fuzzy sets (SFS) is an extension of Picture fuzzy sets providing a larger domain to assign membership degrees. Proportional fuzzy sets (PFS) provides a technique to determine membership degrees with a more consistent and sensitive way. In this article, a multi-expert proportional spherical fuzzy integrated AHP&TOPSIS methodology in which AHP is used for computing the criteria weights and TOPSIS is used for selecting the best RPA alternative is presented. Comparative and sensitivity analyses are also applied to determine the validation and robustness of RPA selection decision.Öğe Silver-Modified Atraumatic Restorative Treatment (SMART) in Managing Carious Primary Molars: 1-Year Clinical Results(Int Soc Fluoride Research, 2025) Aksoy, Merve; Sari, Makbule Buse Dundar; Sozuoz, Melis Arda; Gungor, Erva; Bal, CenkhanPurpose: Silver-modified atraumatic restorative treatment (SMART) is a minimally invasive method that can be utilized for the management of early childhood caries. This study aimed to assess the 12-month clinical success of the SMART technique in the management of carious primary molars. Methods: The analysis (Modified-United States Public Health Service Criteria) was performed on the 3rd, 6th and 12th months clinical records of 53 teeth of uncooperative patients aged between 2-6 years treated with the SMART technique. The included teeth with no spontaneous pain and sensitivity to percussion-palpation, were divided into groups by location (mandibular-maxillary) and carious cavities (occlusal, mesio/disto-occlusal, mesio-occlusal-distal). Fisher Exact Chi-Square test was used to determine the relation between the groups and p-value < 0.05 was accepted as statistically significant. Results: The success rate of SMART for retention, marginal discoloration, and secondary caries in the mandible (84.8%), was higher than the values detected in the maxilla (38.5%) and teeth with occlusal caries were significantly more successful at 12-month assessments (p= 0.038). Mandibular cases and occlusal cavities revealed better results in marginal adaptation assessments (78.8%, and 88.9%, respectively). Conclusions: This paper has the novelty of being the first study assessing the effect of the type of carious cavity and the tooth location in the clinical success of SMART technique. Accordingly, SMART may conclude to be an alternative for the treatment of carious teeth of uncooperative children at least for a period until the child becomes mature to comply with the advanced treatment procedures.Öğe Multiple Linear Regression versus Automatic Linear Modelling -2(Arquivo Brasileiro Medicina Veterinaria Zootecnia, 2024) Genc, S.; Mendes, M.In this study, performances of Multiple Linear Regression and Automatic Linear Modelling are compared for different sample sizes and number of predictors. A comprehensive Monte Carlo simulation study was carried out for this purpose. Random numbers generated from multivariate normal distribution by using RNMVN function of IMSL library of Microsoft FORTRAN Developer Studio composed the material of this study. Results of the simulation study showed that the sample size and the number of predictors are the main factors that lead to produce different results. Although both methods gave very similar results especially when studied with large sample sizes (n >= 100), the Automatic linear modelling is preferred for analyzing data sets due to its simplicity in analyzing data and interpreting the results, ability to present results visually and providing more detailed information especially studying large complex data sets. It will be beneficial to use the Automatic linear modelling especially in analyzing massive and complex data sets for the purposes of investigating the relationships between one continuous dependent and 10 or more predictors and determine the factors that affect the response or target variable. At the same time, it will also be possible to evaluate the effect of each predictor with a more detailed response.Öğe Electrophysiological evaluation of peripheral nerve injuries after the february 6 earthquake in Turkey(Wiley, 2025) Yildirim, A.; Akbas, E.; Inan, R.; Eyigurbuz, T.; Altun, I. Guclu; Hosver, B.; Adatepe, T.[No abstract available]Öğe Increased pulmonary artery-to-aorta diameter ratio in patients with dyspnea is associated with impaired right ventricular systolic function(Wiley, 2025) Ozpinar, U.; Kaya, H.; Aksit, E.[No abstract available]Öğe The Effect of Anti-HLA Antibodies on Graft Rejection after Renal Transplantation: A Retrospective Study(Wiley, 2025) Ozkanay, Hayat; Aksoy, Rasime Derya; Yilmaz, Banu; Uslu, Adam; Kurt, Hasan Anil[No abstract available]Öğe What Predicts Preschoolers' Math Skills? The Role of Paternal Education, Age, SES, and Preschool Attendance(Univ Granada, Fac Ciencias Educacion, 2025) Avci, Kerem; Bedel, Emine FerdaThis study examined the mathematical abilities of preschool children aged 44 to 66 months, regarding variables such as gender, age, handedness, birth order, family socioeconomic status (SES), and preschool attendance. The sample comprised of 288 children attending public preschools. Data were collected using the Test of Early Mathematics Ability-Third Edition (TEMA-3) and a demographic questionnaire. Results indicated that maternal education level is a more powerful and statistically significant predictor of children's early-math abilities compared to paternal education. While higher paternal education is descriptively associated with higher math scores, this relationship does not acquire statistical significance. According to regression analysis age, SES, and preschool attendance significantly predicted mathematical ability. On the contrary, gender, birth order, and handedness were not among the significant predictors.Öğe Attitudes Towards the Use of Robots in the Service Sector on Customer Satisfaction, Revisits and Recommendations Within the Perceived Innovativeness Framework 1(Int Journal Contemporary Economics & Administrative Sciences, 2025) Ergan, Senem; Eru, Oya; Yakin, VolkanWith the rapid advancement of technology, the use of robots in the service sector is becoming increasingly widespread. This study examines how robot usage in the service sector affects customer satisfaction, revisit intention, and recommendations through the lens of perceived innovativeness. Data was collected using a survey method from 380 individuals who had received food and beverage services. The analysis results indicate that perceiving robots as innovative positively influences customer satisfaction. Furthermore, customers' attitudes toward robots in food and beverage services impact on their intention to recommend and revisit the restaurant. In conclusion, the use of robots in the service sector has the potential to enhance customer experience. To increase customer satisfaction, revisit intention, and positive recommendation behavior, businesses must emphasize the innovative features of robots.
