WoS İndeksli Yayınlar Koleksiyonu

Bu koleksiyon için kalıcı URI

https://hdl.handle.net/20.500.12428/2113

Listeleniyor 1 - 20 / 10049

Trace elements (Al, Cd, Cr, Cu, Fe, Mn, Ni, Pb and Zn) in Mytilus galloprovincialis and Tapes decussatus from Faro and Ganzirri Lakes (Sicily, Italy): Flow cytometry applied for hemocytes analysis
(Elsevier GmbH, 2021) Parrino, Vincenzo; Costa, Gregorio; Giannetto, Alessia; De Marco, Giuseppe; Cammilleri, Gaetano; Acar, Ümit
Background: Trace elements present in sessile molluscs, are important because they are used in human consumption and it has significantly increased in recent years. While their filtering of the water can lead to their build-up of organic and inorganic materials that can be sampled and analyzed, this can also lead to bioaccumulation of harmful substances, such as essential and non-essential elements, that can harm the human health if in taken in high concentrations or for a long period of time. Methods: In the present study, the trace metal content (Al, Cd, Cr, Cu, Fe, Mn, Ni, Pb and Zn) of two sessile crustaceans, 20 Mytilus galloprovincialis (mussel) and 20 Tapes decussatus (clam) in Faro and Ganzirri Lakes (Messina, Sicily, Italy) were analyzed. Haemolymph samples were taken on both molluscs in order to analyze the haemocyte population by flow cytometric analysis. Unpaired t-tests were used to determine significant differences for the essential and non-essential metallic elements concentrations in the lake waters and in the tissues of M. galloprovincialis and T. decussatus and for hemocyte populations R1 (halinocytes) and R2 (granulocytes). Results: The results suggested that that in Faro Lake, the tissue Al, Cr and Pb levels in M. galloprovincialis were higher than those for T. decussatus, in contrast to Mn, Fe, Ni, Cu, Zn and Cd, which were higher in T. decussatus. Unpaired t-tests showed that there were significantly higher proportions of halinocytes in M. galloprovincialis versus T. decussatus for both Faro Lake (41.8 % vs. 24.3 %; P < 0.001) and Ganzirri Lake (43.0 % vs. 22.4 %; P < 0.001). In contrast, while there were significantly higher proportions of granulocytes in Faro Lake (21.2 % vs. 9.1 %; P < 0.001), this difference was not seen for the granulocytes of M. galloprovincialis versus T. decussatus in Ganzirri Lake (9.6 % vs. 13.0 %). Conclusion: This study shows that M. galloprovincialis and T. decussatus can indeed bioaccumulate some of these metal, such that activation of the immune responses is specific to certain cell types. Future research must focus on the balance of trace elements in the consumption of these shellfish, and analyzes with more sophisticated tools can be used to diagnose the increased concentration of trace elements and the quantification of trace metals from shellfish to clams.
The impact of acute cold water stress on blood parameters, mortality rate and stress-related genes in Oreochromis niloticus, Oreochromis mossambicus and their hybrids
(Elsevier Ltd, 2021) Yılmaz, Sevdan; Ergün, Sebahattin; Çelik, Ekrem Şanver; Banni, Mohamed; Ahmadifar, Ehsan; Dawood, Mahmoud A. O.
This study aims to evaluated the response of Oreochromissp. to cold stress. Two experiments were conducted involving a total of 1080 juvenile Oreochromis niloticus, O. mossambicus, O. niloticus♂ × O.mossambicus♀=F1♂ × O.mossambicus ♀ (Hybrid 1; H1) and O. mossambicus♂ × O. niloticus♀ (Hybrid 2; H2). In the 1st experiment, fish were exposed to cold water (12 °C) for 24 h and then hematological parameters, serum biochemical variables, innate immune responses, antioxidant status, and liver gene expression responses (hsp70, hsp27, hsp90, hsp40, cat, sod, eef1a1 and calreticulin) were analyzed. Hematological and serum biochemical responses involved species-specific differences. At optimal temperatures (28 °C), respiratory burts activity (RBA) and myeloperoxidase (MPO) values of H1, H2 and O. mossambicus were significantly higher than O. niloticus (p< 0.05). While the RBAvalue of O. mossambicus decreased after exposure to cold water (p< 0.05), lysozyme activities of O. niloticus and H2 and MPO activities of all experimental fish increased significantly (p< 0.05). At control conditions (28 °C), cortisol levels were found to be higher in O. mossambicus than in H1 and O. niloticus (p< 0.05). A significant increase in cat and sod transcripts was observed in liver of fish being very pronounced in O. mossambicus and H2. The highest up-regulation was observed for hsp70 target where the lowest but significant up-regulation was observed for hsp90 gene. In 2nd experiment, water temperature was gradually decrease from 28 °C to 12 °C (average, 1 °C/1 h).Survival rates of H1 and H2 were found to be different compared to O. mossambicus and O. niloticus (p< 0.05) after 20 days of cold water challenge.O. mossambicus was the most cold-sensitive group, followed by the H2, H1 and O. niloticus. Our data should be carfully considered in view of the possible physiological and anti-stressor responses being species-specific in fish.
Mechanically stable superhydrophilic antifog surface by microwave assisted sol-gel method
(Elsevier B.V., 2021) Okkay, Hikmet; Satı, Sadık; Cengiz, Uğur
In this study, optically transparent and mechanically stable of superhydrophilic composite thin films were fabricated via a low-cost one-step one pot microwave-assisted sol-gel technique. The microwave reaction time was optimized according to surface characterization of homo TMOS surfaces. The reaction time was arranged as 17.5 min having low cost compared to the conventional sol-gel technic. The wettability performance and antifogging behavior of PVA-TMOS composite films were investigated according to variation of the PVA content. The static contact angle values of the composite surfaces were found to vary between 30o and 5o. Superhydrophilic surface having tilt angle is 9o showed a good antifogging performance. Mechanical durability of the composite surface was also characterized by scratching and adhesive tape test. In addition, the time depending water contact angle was also measured for 100 days. It is found that TMPV96 composite film having 0.096 (wt,%) content of PVA showed higher mechanical performance with transparent superhydrophilic surface.
Synthesis and multicolor, photophysical, thermal, and conductivity properties of poly(imine)s
(Elsevier B.V., 2021) Kaya, İsmet; Solak, Elif; Kamacı, Musa
Background: Thiazole-based conjugated have been attracted much attention due to their desirable photophysical properties. Based on this, we aimed to prepare thiazole-based poly(imine)s with tunable multicolor emission behavior in the present paper. Methods: Thiazole-based Schiff bases and poly(imine)s were prepared via condensation, and oxidation reactions, respectively. The tunable multicolor behavior of the poly(imine)s was also clarified using fluorescent measurements. Findings: The conductivity, thermal, photophysical, multicolor, morphological and electrochemical properties of the thiazole-based compounds were also clarified. Multicolor behavior of the poly(imine)s was demonstrated that they were emitted blue, green, and yellow emission colors when excited at 350, 420, and 480 nm, respectively. Thermal properties showed that the (poly(imine)s were exhibited good thermal stability. It was found that the thiazole-based poly(imine)s were exhibited a semiconductor behavior after iodine doped. The results indicated that the prepared poly(imine)s were exhibited tunable multicolor property with good thermal stability, and electrical conductivity.
The effect of simulated vibration frequency on the physico-mechanical and physicochemical properties of peach during transportation
(Elsevier Ltd., 2021) Dağdelen, Çiğdem; Aday, Mehmet Seçkin
Loss in fresh fruit and vegetables during transportation occurs mainly due to their susceptibility to mechanical damage. The quality loss caused by this damage depends on the shock and vibration frequencies. In this study, the effect of different vibration frequencies (5 Hz, 10 Hz, and 15 Hz) on the physico-mechanical and physico-chemical properties of peach was investigated. The parameters such as energy absorption, mechanical hysteresis, and deformation volume were increased whereas mean geometric diameter, surface area, volume, degree of elasticity, deformation energy, and modulus of elasticity were decreased. Regarding physicochemical properties, pH and total soluble solid parameters increased whereas lightness (L*) value of peach decreased. The highest level of damage and mold growth were observed on the peach treated with 15 Hz frequency followed by 10 Hz and 5 Hz, respectively. The effect of all the frequencies on the physico-mechanical and physico-chemical properties of peach was statistically different. The results indicated that the increase in the vibration frequency causes higher mechanical damage in peach.
Optimization of pretreatment and enzymatic hydrolysis conditions of tomato pomace for production of alcohols and esters by Kluyveromyces marxianus
(Elsevier Ltd., 2021) Kılmanoğlu, Hilal; İşleten Hoşoğlu, Müge; Güneşer, Onur; Karagül-Yüceer, Yonca
Tomato pomace (TP) is generated as a natural by product in a significant amount in the tomato processing industry, and it is a good source of lignocelluloses to produce some high-value products from fermentable sugars (FS). The present study was performed to produce FS by using either ultrasound-assisted dilute acid (UADA) or heat-treated dilute acid (HTDA) pretreatments of TP followed by enzymatic hydrolysis (EH). When HTDA and UADA were compared in terms of FS (g/L) concentration, HTDA pretreatment generally produced more FS content than UADA. The optimum conditions for HTDA pretreatment were the application of 2.5% H2SO4, 10% (w/v) solution of TP, and heating at 121 °C for 6 min, which yielded 31 g/L FS concentration. Beside the optimized conditions for EH of HTDA, pretreated TP required 1.5% of enzyme concentration and 6 h of hydrolysis time. In conclusion, the most abundant volatile organic compounds (VOCs) produced by K. marxianus in final tomato pomace hydrolysate (TPH) were isoamyl alcohol, phenyl ethyl alcohol, ethyl acetate and phenyl ethyl acetate in a 5-L bioreactor. Nine descriptive sensory terms were developed to characterize fermented TPH. The rose and sweet floral aromas were defined as aroma characteristics for TPH fermented by K. marxianus.
Modification of halloysite clay nanotubes with various alkyl halides, and their characterization, blood compatibility, biocompatibility, and genotoxicity
(Elsevier Ltd, 2021) Can, Mehmet; Demirci, Şahin; Yıldırım, Yıldız; Çakır Çoban, Canan; Türk, Mustafa; Şahiner, Nurettin
Halloysite nanotubes (HNTs) clay were modified with alkyl halides, bromoethane (BrE), bromodecane (BrD), and bromooctadecane (BrOD), respectively. The FT-IR spectra of modified HNTs demonstrated an increase in the intensity of aliphatic –CH2 peaks at 2920 and 2850 cm−1 proportional to the number of C atoms in the modifying agent confirming the success of chemical modification with corresponding alkyl halides. Surface charge of NaOH treated HNTs, −65.7 ± 5.1 mV was increased to −37.1 ± 2.4, −40.6 ± 5.3, and −44.7 ± 1.9 mV, respectively upon chemical modification with BrE, BrD, and BrOD. The Surface area of the HNT clays, 43.2 ± 1.3 m2/g was also increased to 59.8 ± 2.7, 56.9 ± 2.1, and 47.9 ± 1.7 m2/g for BrE, BrD, and BrOD modified HNT clays, respectively. Base-activated HNT clays at 1 mg/mL concentration found to be nonhemolytic with 3.5 ± 1.2% hemolysis ratio, whereas HNT-BrOD clays were slightly exceeded hemolytic safety level with 6.6 ± 0.2% hemolysis induction. Base-activated HNT and HNT-BrOD clays were found to show antithrombogenic character with more than 100% blood clotting indexes,107.6 ± 1.8, and 106.5 ± 1.9%, respectively. Cytotoxicity studies of HNTs on L929 fibroblast cells revealed that HNTs in 12.5–200 μg/mL concentration range were shown dose-dependent cell viability, and above 50% cell viability was maintained at 200 μg/mL in all forms of HNT based clays administered.
Ultrasonically sprayed cobalt oxide thin films: Enhancing of some physical properties by nickel doping
(Elsevier B.V., 2021) Kuş, Esra; Küçükkarslan, Ayşe; Demirselçuk, Barbaros; Sarıca, Emrah; Akyüz, İdris; Bilgin, Vildan
In this study, the effect of Ni doping (3, 6, 9 at%) on structural, optical, electrical and magnetic properties of Co3O4 films was reported. Films were grown at 300 ± 5 °C substrate temperature via ultrasonic spray pyrolysis (USP) technique. The structural analyses showed that undoped and Ni (3%) doped films exhibit an amorphous structure. Ni doping at higher ratios caused the films to have improved crystallinity. Optical band gap values the films were found to be between 2.03 and 2.08 eV with an additional sub-band corresponding to energies varying between 1.35 and 1.46 eV. The electrical conductivity values of the films increased significantly depending on the Ni doping. The hysteresis curves of the films showed that the films have weak ferromagnetic properties. Ni doping significantly improved the structural and electrical properties of Co3O4 films making them suitable materials for technological applications.
Deep neural network ensemble for on-the-fly quality control-driven segmentation of cardiac MRI T1 mapping
(Elsevier B.V., 2021) Hann, Evan; Popescu, Iulia A.; Zhang, Qiang; Gonzales, Ricardo A.; Barutcu, Ahmet
Recent developments in artificial intelligence have generated increasing interest to deploy automated image analysis for diagnostic imaging and large-scale clinical applications. However, inaccuracy from automated methods could lead to incorrect conclusions, diagnoses or even harm to patients. Manual inspection for potential inaccuracies is labor-intensive and time-consuming, hampering progress towards fast and accurate clinical reporting in high volumes. To promote reliable fully-automated image analysis, we propose a quality control-driven (QCD) segmentation framework. It is an ensemble of neural networks that integrate image analysis and quality control. The novelty of this framework is the selection of the most optimal segmentation based on predicted segmentation accuracy, on-the-fly. Additionally, this framework visualizes segmentation agreement to provide traceability of the quality control process. In this work, we demonstrated the utility of the framework in cardiovascular magnetic resonance T1-mapping - a quantitative technique for myocardial tissue characterization. The framework achieved near-perfect agreement with expert image analysts in estimating myocardial T1 value (r=0.987, p<.0005; mean absolute error (MAE)=11.3ms), with accurate segmentation quality prediction (Dice coefficient prediction MAE=0.0339) and classification (accuracy=0.99), and a fast average processing time of 0.39 second/image. In summary, the QCD framework can generate high-throughput automated image analysis with speed and accuracy that is highly desirable for large-scale clinical applications.
Amperometric nonenzymatic glucose biosensor based on graphite rod electrode modified by Ni-nanoparticle/polypyrrole composite
(Elsevier Inc., 2021) Emir, Gamze; Dilgin, Yusuf; Ramanaviciene, Almira; Ramanavicius, Arunas
This study reports non-ezymatic electrocatalytic amperometric glucose biosensor based on a graphite rod electrode (GRE) modified with biomimetic-composite consisting of Ni nanoparticles (Ni-NPs) and polypyrrole (Ppy) prepared by 1 cycle electro polymerization of pyrrole monomer (Ni-NPs/Ppy(1)/GRE). During the modification of GRE, the electropolymerization of pyrrole and the electrodeposition of Ni-NPs onto GRE surface were consequentially performed by potential cycling. Surface morphology of Ni-NPs/Ppy(1)/GRE electrode was evaluated by atomic force microscopy and scanning electron microscopy based imaging, and electrochemical characterization of electrodes was performed by electrochemical impedance spectroscopy and cyclic voltammetry. Cyclic voltammograms recorded in the presence of glucose show that Ni-NPs/Ppy(1)/GRE at + 500 mV vs Ag/AgCl exhibits efficient electrocatalytic oxidation activity towards glucose, while the oxidation of glucose was not observed at a bare GRE. Amperometric sensing of glucose was performed by Ni-NPs/Ppy(1)/GRE at constant + 450 mV vs Ag/AgCl electrode potential in 0.10 mol L−1 NaOH. Ni-NPs/Ppy(1)/GRE-based sensor, which was characterized by a wide linear glucose determination range between 1.0 and 1000 µmol L−1 with a limit of detection of 0.4 µmol L−1 and a sensitivity of 2873 µA mmol−1 L cm−2. The applicability of here reported Ni-NPs/Ppy(1)/GRE-based sensor has been demonstrated by the determination of glucose concentrations in real samples.
The effect of nanoparticle sizes on the structural, optical and electrical properties of indium sulfide thin films consisting of In2S3 and In6S7 phases
(Elsevier B.V., 2021) Demir, Ramazan; Göde, Fatma; Güneri, Emine; Emen, Fatih Mehmet
Indium sulfide thin films consisting of In2S3 and In6S7 phases were synthesized onto microscope glass substrates with different nanoparticle size using the chemical bath deposition method (CBD). Immediately after obtaining the films, they were annealed at 400°C for 1 h in reduced media in order to get better crystallization. The effect of nanoparticle sizes on the structural, compositional, optical, and electrical properties of the films was investigated. The films were characterized by x-ray diffraction (XRD), scanning electron microscope (SEM), energy dispersive x-ray spectrometry (EDS), UV–Vis spectroscopy and sheet resistivity measurements. The XRD spectra revealed the existence of both the cubic In2S3 and monoclinic In6S3 phases. From the SEM micrographs, the deposited films showed dense and good coverage of the surface with cracks. Moreover, nanoparticle sizes increased from 53 nm to 142 nm with increasing deposition time as well as film thickness. With an increase in nanoparticle size, the S/In ratio in the films decreased from 1.74 to 1.21 showing sulfur deficiency in the deposited films. The direct band gap (Eg) of the films decreased from 3.35 eV to 2.70 eV with increasing nanoparticle size. The sheet resistivity of the films decreased from 1.69 × 107Ω/Sq to 4.61 × 103Ω/Sq. The obtained results demonstrate that nanoparticle sizes effected the structural, compositional, optical and sheet resistivity of the films.
Synthesis, spectral properties, crystal structure and theoretical calculations of a new geminal diamine: 2,2,2-Trichloro-N,N′-bis(2-nitrophenyl)-ethane-1,1-diamine
(Elsevier B.V., 2021) Aydın, Fatma; Arslan, N. Burcu
A new 2,2,2-trichloro-N,N׳-bis(2-nitrophenyl)-ethane-1,1-diamine was synthesized by the reaction of 2-nitroaniline in DCM with the chloral formed by distillation of chloral hydrate over concentrated H2SO4. The structure of the title compound was identified by means of FT-IR, 1H NMR, and 13C NMR spectroscopic techniques. The crystal structure of the title compound has also been examined by using X-ray crystallographic techniques and found to be crystallized in the monoclinic crystal system and space group P21/n with the unit cell parameters: a = 7.7075(12) Å, b = 7.7396(10) Å, c = 28.247(4) Å, β = 93.602(5)°, V = 1681.7(4) Å3, Dx = 1.602 Mg m − 3, and Z = 4 respectively. The calculated electronic structure properties of the title molecule such as HOMO-LUMO analysis, molecular electrostatic potential (MEP) map, and the Mulliken charge distributions were investigated by using the density functional theory (DFT) method. Theoretically calculated values exhibit the chemically hard, high kinetic stable and less reactive molecule.
Synthesis and characterization of magnetic ZnCl2-activated carbon produced from coconut shell for the adsorption of methylene blue
(Elsevier B.V., 2021) Karaer Yağmur, Hatice; Kaya, İsmet
In this research, a magnetic-activated carbon composite was synthesized to investigate its adsorption to methylene blue dye. Active carbon (ACz) was produced by ZnCl2 activation of coconut shell (char: ZnCl2, 2:1). Magnetic activated carbon (MACz) was prepared via an easy method by chemical co-precipitation of Fe3+/Fe2+. The pore diameter, pore-volume, and surface area of MACz were determined from N2 adsorption isotherms. The ACz and MACz were characterized by several techniques such as BET, SEM/EDX, FT-IR, XRF, VSM, TGA, and pHpzc analysis. The average particle size, particle size distribution, and zeta potential of MACz were determined by Zetasizer. The zero point charge of the MACz was determined as approximately 4.9 pH. Moreover, the adsorption by MACz was investigated as kinetically and thermodynamically for removal of methylene blue (MB) from aqueous solution. The kinetics and thermodynamic parameters were also calculated. According to the results, the adsorption process was determined as endothermic. The Langmuir and Freundlich isotherms models were used and it was found that adsorption of MB onto MACz best fitted to Freundlich model according to RMSE, SSE, and R2 values. The maximum adsorption capacity of the composite was calculated as 156.25 mg/g. Thermodynamic parameters (ΔHo, ΔGo, and ΔSo) were also calculated, which revealed that the adsorption process is spontaneous.
Dye sensitized solar cell-based optoelectronic device using novel [Ru(L1)(L2)(NCS)2] complex
(Elsevier B.V., 2021) Dayan, Osman; Gençer İmer, Arife; Tercan, Melek; Dere, Ayşegül; Al-Sehemi, Abdullah G.; Al-Ghamdi, Ahmed A.; Yakuphanoğlu, Fahrettin
A dye sensitized solar cell-based photodiode was prepared using novel [Ru(L1)(L2)(NCS)2] complex for solar energy and optoelectronic applications. The new heteroleptic ruthenium(II) complex [Ru(L1)(L2)(NCS)2], was synthesized from the reaction of (pyridyl)benzimidazole ligands. The possible usage of [Ru(L1)(L2)(NCS)2] complex in dye synthesized solar cell-based photodiode was investigated using electrical and capacitance characteristics. The device was irradiated under various solar light intensities. The change in photocurrent of the device confirms the photoconducting behavior of prepared device. The device exhibited both the photocapacitance and photoresponse behavior with solar illumination. The obtained optoelectrical results suggest that the studied photodiode with [Ru(L1)(L2)(NCS)2] complex could be used in optoelectronic device for optical switching and controlling applications.
Calculation Of The Damping Constant (FWHM), The Relaxation Time, And The Activation Energy As A Function Of Temperature For DmaCd(N3)3
(Elsevier B.V., 2021) Kurt, Arzu
The Raman frequencies of τ(CH3), υs(CNC), υ1(N3) and δ(CH3) modes, the IR frequencies of δ(NH2) and ρ(NH2) modes, and the corresponding FWHM values for these modes in DMACd(N3)3 were analyzed by using the experimental data from the literature for both ferroelastic and paraelastic phases. In these analyses, the Raman and the IR frequencies of these modes were associated with the order parameter calculated from the molecular field theory with regard to the structural phase transition (Tc=174 K) in DMACd(N3)3, the frequencies and the damping constants of τ(CH3), υs(CNC), υ1(N3), δ(CH3), δ(NH2), and ρ(NH2) modes as a function of temperature through the model of pseudospin (dynamic disorder of DMA+ cations and partially N3 anion), phonon coupling (PS) model, and the energy fluctuation (EF) model by analyzing the experimental data for the frequencies and FWHM of these modes in hybrid organic-inorganic perovskite. Moreover, the relaxation time and the activation energy were calculated for all these modes at various temperatures by using the damping constants (FWHM) for the PS and EF models studied in DMACd(N3)3. The results of the present research showed that the calculated Raman and IR frequencies with the damping constants of τ(CH3), υs(CNC), υ1(N3), δ(CH3), δ(NH2), and ρ(NH2) modes adequately accounted for the experimental data in DMACd(N3)3. The calculated activation energies for these modes were found to be acceptable compared to the values available in the literature and the kBTc values at the critical temperature. This method for calculating the frequencies (IR and Raman) and FWHM of these modes that were associated with the phase transitions could also be applied to some other hybrid organic-inorganic perovskites.
Evaluation of DNA damages in congenital hearing loss patients
(Elsevier B.V., 2021) Çağlar, Özge; Çobanoğlu, Hayal; Uslu, Atilla; Çayır, Akın
In the current study, we aimed to compare the level of genetic damages measured as micronucleus (MN), nucleoplasmic bridge (NPB), and nuclear bud formation (NBUD) in congenital hearing loss patients (n = 17) and control group (n = 24). The cytokinesis-blocked micronucleus assay (CBMN) was applied to the blood samples to measure the frequency of the markers in both groups. The frequencies of MN of hearing loss patients were found to be consistently significantly higher than those obtained for the control group (p < 0.0001). Similarly, we found significantly higher frequency of NPB in patients was obtained for the patient group (p < 0.0001). Finally, the frequencies of NBUD in patients is significantly higher than the level measured in the control group (p < 0.0001). Furthermore, the age-adjusted MNL, BNMN, NPB, and NBUD frequencies in the patients were significantly higher than those obtained in the control group. We observed that the frequency of MN in patients was positively correlated with NBUD frequency which may indicate a common mechanism for these biomarkers in the patient group. We found, for the first time, that there were statistically significant higher levels of MN, NPB, and NBUD in sensorineural hearing loss patients. Since the markers we evaluated were linked with crucial diseases, our findings might suggest that sensorineural hearing loss patients are susceptible to several crucial diseases, especially cancer. Furthermore, the results demonstrated the significance of the MN, NPB, and NBUD level and thus provides a potential marker for the diagnosis of congenital hearing loss patients.
A rare presentation of Susac syndrome: Report of three pediatric cases
(Elsevier B.V., 2021) Çitçi Yalçınkaya, Beyza; Ertürk Çetin, Özdem; Kılıç, Hüseyin; Demirci, Onat; Çokyaman, Turgay; Uygunoğlu, Uğur
Susac syndrome is a rare disorder that is clinically characterized by encephalopathy, retinopathy and hearing loss. Most of the reported cases in the literature are adult patients, pediatric presentation is extremely rare. Here we present three pediatric patients aged between 10-15; diagnosed as Susac syndrome. They all had thalamic involvement in addition to typical callosal lesions. All of the three patients had a monophasic course and good treatment response.
Synthesis and characterization of biodegradable and antioxidant phosphazene-tannic acid nanospheres and their utilization as drug carrier material
(Elsevier Ltd, 2021) Önder, Alper; Özay, Hava
In this study, hexachlorocyclotriphosphazene (HCCP) and tannic acid (TA) were used at different stoichiometric ratios to synthesize cyclomatrix-type polymeric materials with different surface features and dimensions. Using different reactive ratios, the structure and surface functional groups of the synthesized polymeric particles were explained using Fourier-Transform Infrared Spectroscopic (FTIR), Scanning Electron Microscope (SEM), Energy-dispersive X-ray spectroscopy (EDX), X-ray Photoelectron Spectroscopy (XPS) and Thermogravimetric (TG) analysis techniques. With morphologically fully spherical structure and mean 234.82 ± 49.37 nm dimensions, Phz-TA (4:1) nanospheres were researched for in vitro biodegradability, antioxidant features, and usability as a drug release system. In vitro biodegradability of Phz-TA (4:1) nanospheres was investigated at pH = 7.0 and pH = 1.2. Determined to degrade in 8–10 h at these pH values, nanospheres were used for releasing of Rhodamine 6G as a model drug. Due to the rich phenolic structure of the contained tannic acid units, nanospheres were determined to simultaneously have antioxidant features. Thus, this study determined that Phz-TA nanospheres with in vitro biodegradability and antioxidant features are promising polymeric materials for use as a potential drug-carrier in the future.
New photometric analysis of hot Jupiter: WASP-135b
(Elsevier B.V., 2021) Öztürk, Oğuz; Erdem, Ahmet
We report photometric follow-up observations of WASP-135b obtained using the 1.23-m telescope at Calar Alto Observatory and 1.00-m telescope at TÜBİTAK National Observatory during the 2017 and 2018 observational seasons. Eight new transit light curves of WASP-135b were analyzed with JKTEBOP code. The ratio of the planet radius to radius of host star, fractional radius of host star, and orbital inclination of WASP-135b were found to be 0.138 ± 0.002, 0.181 ± 0.008 and 82.44 ± 0.64 degrees, respectively. Planetary radius of WASP-135b was derived from transit parameters to be 1.075 ± 0.150 RJ. The transit ephemeris of WASP-135b was also updated using the maximum likelihood method (MLM). 165 well-known hot Jupiters (HJs) were selected from the Exoplanet Data Explorer database and the classification of these HJs together with WASP-135b, based on their equilibrium temperatures and Safronov numbers, is discussed.
Einstein-Rosen universe with scalar field in f(R,T) theories
(Elsevier B.V., 2021) Taṣer, Dog̃ukan; Dog̃ru, Melis Ulu
Non-static Einstein–Rosen universe with scalar field is examined via two different selection of f(R,T) models. Firstly, we analyzed Einstein–Rosen universe with scalar field in f(R,T)=R+2f(T) model. Then, we constructed field equations for f(R,T)=f1(R)+f2(R)f3(T) model, as well. For both models, exact solutions of field equations have been attained without considering any approximation or restriction. Whether scalar field corresponds to phantom and/or quintessence scalar field are investigated for each models.

Güncel Gönderiler