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Determination of the Biological Parameters of Graphosoma lineatum L. Heteroptera, Pentatomidae on Different Foods
(Ankara Üniversitesi, 2009) Koçak, Erhan; Emre, H. Tevfik; Şahin, Ali Kürşat; Barış, Aydemir; Gökdoğan, Atilla; Başaran, M. Selçuk
Graphosoma lineatum is the suitable host of Sunn pest Eurygaster spp. egg parasitoids. Fecundity, adult lifespan, preoviposition, oviposition and postoviposition periods, nymph development periods according to nymph stages and as total, nymph ratios of reaching to adult stage of Grapohosoma lineatum L. were determined on different plants from Apiaceae. Studies were carried out in laboratory under 27±2ºC temperature, 45±5% RH and 16 hours photoperiod conditions. Plants were presented weekly to insects collecting them from preflowering stage to ripping stage June–September, 2006 from Ayaş, Beypazarı and Kızılcahamam counties in Ankara province. The average fecundity of the insect on Torilis arvensis Huds. , Daucus carota L. , Heracleum platytaenium Boiss. , Conium maculatum L. and Astrodaucus orientalis L. as 178.0, 185.2, 196.0, 415.0 and 170.2, respectively; and the female lifespan was 56.67, 56.67, 51.50, 71.00 and 60.00 days; male lifespan was 55.67, 73.17, 58.83, 88.50 and 49.17 days; preoviposition period was 21.66, 12.50, 15.33, 11.50 and 18.00 days; oviposition period was 31.50, 33.67, 26.83, 57.17 and 35.83 days; postoviposition period was 3.50, 8.83, 9.00, 2.33 and 6.16 days; nymphs ratios reaching to adult stage 47.50%, 82.50%, 82.50%, 85.00% and 67.50%; and total nymphal period was 25.70, 22.20, 20.75, 18.85 and 24.10 days. The shortest nymhp development periods were determined as 1, 3, 2, 4 ve 5 according to nymph stages. Generation durations as the shortest 35.35 days on C. maculatum and the longest 51.36 days on T. arvensis were determined. These results show that C. maculatum and H. platytaenium were the most suitable food sources while T. arvensis and A. orientalis were not for G. lineatum [TR] Süne Eurygaster spp. yumurta parazitoitleri için uygun konukçu olan Grapohosoma lineatum L. ’un fekonditesi, erginlerin yaşam süreleri, preovipozisyon, ovipozisyon, postovipozisyon süreleri ile nimflerinin toplam gelişme süresi, dönemlerine göre gelişme süresi, döl nesil süreleri ve ergin olma oranları laboratuvar koşullarında Apiaceae familyasından farklı bitkilerde belirlenmiştir. Çalışmalar, 27±2ºC sıcaklık, %45±5 orantılı nem ve aydınlanma süresi 16 saat olan uzun gün koşullarının sabit tutulduğu iklim odasında gerçekleştirilmiştir. Bitkiler Ankara’nın Ayaş, Beypazarı ve Kızılcahamam ilçelerinden çiçeklenme öncesi dönemden tohum olgunlaşma dönemine kadar Haziran-Eylül 2006 haftada bir toplanarak böceklere sunulmuştur. Fekondite; Torilis arvensis Huds. , Daucus carota L. , Heracleum platytaenium Boiss. , Conium maculatum L. ve Astrodaucus orientalis L. bitkileri için sırasıyla ortalama 178.0, 185.2, 196.0, 415.0 ve 170.2 adet yumurta olarak bulunmuştur. Dişi yaşam süresi sırasıyla ortalama 56.67, 56.67, 51.50, 71.00 ve 60.00 gün; erkek yaşam süresi sırasıyla ortalama 55.67, 73.17, 58.83, 88.50 ve 49.17 gün; preovipozisyon süresi sırasıyla ortalama 21.66, 12.50, 15.33, 11.50 ve 18.00 gün; ovipozisyon süresi sırasıyla ortalama 31.50, 33.67, 26.83, 57.17 ve 35.83 gün; postovipozisyon süresi sırasıyla ortalama 3.50, 8.83, 9.00, 2.33 ve 6.16 gün; nimflerin ergin olma oranı sırasıyla %47.50, % 82.50, %82.50, %85.00 ve %67.50; nimflerin toplam gelişme süresi sırasıyla ortalama 25.70, 22.20, 20.75, 18.85 ve 24.10 gün olarak bulunmuştur. En kısa nimf gelişme süresi sırasıyla 1, 3, 2, 4 ve 5. dönemler şeklinde sıralanmıştır. Döl süresinin en kısa 35.35 gün ile C. maculatum’da ve en uzun ise 51.36 gün ile T. arvensis’te tamamlandığı belirlenmiştir. Çalışma sonucunda, baldıran ismiyle bilinen ve güçlü alkaloidleriyle tanınan C. maculatum’un G. lineatum’un kültüre alınmasında diğer bitkilerden çok daha önde olduğu ve H. platytaenium‘un da onu takip ettiği belirlenmiştir. T. arvensis ve A. orientalis’in uygun konukçular olmadıkları sonucuna varılmıştır
IDEAL CONVERGENCE IN FUZZY METRIC SPACES
(Turkic World Mathematical Soc, 2025) Or, A.; Karabacak, G.
In this paper, the concepts of K-convergence, K-Cauchy sequences, K-& lowast;- convergence, and K-& lowast;-Cauchy sequences in fuzzy metric spaces is proposed. Also, a few fundamental properties of these concepts are investigated. Then, the concepts of K-limit and /C-cluster points of a sequence in these spaces is defined. Afterwards, some of their basic properties is examined. Finally, the need for further research is discussed.
Evaluation of the opacity and protein quality of maize kernels by image analysis
(Maydica-Ist Sper Cerealicoltur, 2025) Uckan, Kerem; Sentruk, Nilay; Uydas, Melike; Kahr, Fatih
The protein content and quality in maize significantly influence grain quality, driving global efforts to develop high-protein-quality genotypes. Opacity serves as a key phenotypic selection criterion in these efforts due to its relationship with essential amino acid content. This study investigates the differentiation of opaque maize kernels using computer-aided software and explores the relationship between opacity levels and color spaces (RGB, HSV, Lab). Seed samples from 10 maize genotypes (1000 seeds) with varying opacity levels were imaged on a light table in embryo-up and embryo-down orientations. Particle analysis and thresholding performed in R determined opacity levels and provided numerical data for RGB, HSV, and Lab color spaces. Protein, lysine, and tryptophan contents were analyzed through reference methods. Correlation and regression analyses assessed relationships between opacity levels (visual and image-processed) and biochemical components, and color space channels. Protein content ranged from 6.66% to 11.62%, lysine from 0.266% to 0.450%, and tryptophan from 0.034% to 0.092% among opacity groups. Relationships between visual and image-processed opacity levels showed R2 = 0.57 (embryo-up) and R2 = 0.65 (embryo-down). Notably, channels of the HSV color space correlated with lysine and tryptophan contents. This study demonstrates that image processing effectively evaluates opacity levels and protein quality in maize using color space data, offering a promising tool for phenotypic selection.
Determining the Biogas Potential from Animal Manure in Canakkale and Creating an Electricity Generation Capacity Map
(Int Journal Renewable Energy Research, 2025) Oguz, Emrah; Oguz, Yuksel
In this study, the biogas production potential from animal manure in Canakkale was determined and the electrical energy production capacity of the province was determined. According to the 2021 cattle, small ruminant, and poultry numbers received from the Provincial Directorate of Agriculture and Forestry, the cattle, small ruminant, and poultry manure amounts of all districts were calculated. Then, the amount of biogas that could be produced was calculated based on this data digital maps of the province were created by calculating the equivalent electrical energy production values of all districts with the biogas energy potentials that can be obtained. It has been calculated that a total of 119,715,927.80 m(3) of biogas can be obtained annually throughout the province. The total annual equivalent electrical energy of this potential is 562,664.86 MWh. In line with the data obtained, it has been determined that Canakkale has a 70 MW biogas power plant potential.
Do uncertainties and risks have an impact on cryptocurrency returns? Evidence from the symmetric and asymmetric fourier quantile causality test
(Univ Chile Dept Economics, 2025) Kilci, Esra N.; Yilanci, Veli
This paper explores the impact of uncertainties and risks on the returns of cryptocurrencies by considering the two dimensions of uncertainty sourcing from economic policy uncertainty and geopolitical risk. Therefore, we analyze whether there is a causality from the global economic policy uncertainty (GEPU) and geopolitical risk (GPR) to the cryptocurrency returns in the period from 2015:01 through 2023:05. In our analysis, we use the GEPU and GPR indexes as independent variables and the historical values of Bitcoin, Ethereum, Litecoin, Ripple, Monero, and Dash as dependent variables. We employ the Fourier augmented causality test considering the original series, and also the positive and negative components of the series. Our findings reveal that the GPR has predictive power for all cryptocurrencies while GEPU has not predictive power for only Bitcoin. Furthermore, we find evidence of the causality nexus that runs from negative shocks of GEPU to the negative shocks of Litecoin and Ripple, and from the negative shocks of GPR to the negative shocks of Litecoin and Monero indicating when there are significant decreases at the GEPU, these values can be used to predict the decreases of Litecoin and Ripple. Similarly, we can also imply it for the causality relationship from GPR to Litecoin and Monero. When we consider there might be a causal relationship not only between shocks of the same type but also between different types of shocks we find that there is unidirectional causality from negative shocks of GEPU to the positive shocks of Dash, Ethereum, and Monero at the high return phase, and from positive shocks of GEPU to the negative shocks of Ethereum, and from positive shocks of GPR to the negative components of Bitcoin, Ethereum, and Ripple at the bearish market conditions.
A REVISIT OF TOURISM AND GROWTH NEXUS IN THE PROVINCES OF CHINA BASED ON BOOTSTRAP PANEL CAUSALITY TEST WITH A FOURIER FUNCTION
(Inst Economic Forecasting, 2024) Chang, Tsangyao; Yilanci, Veli; Wang, Mei-Chih; Min, Jennifer
In this study, we collect annual data for 30 regions in China using tourism receipts and gross domestic product over the period of 1980-2020. Empirical results from Bootstrap Toda-Yamamoto Granger Causality test with a Fourier function, which consider both cross-sectional dependence and multiple smooth breaks, support the evidence of feedback hypothesis in most of the regions except for Jilin that we find the validity of tourism-led-growth hypothesis, Shanxi, and Qinghai where we find the supportive evidence of growth-led-tourism hypothesis, and for Gansu, Ningxia, and Xinjiang where we find the strong evidence of neutrality hypothesis. These results further show the importance of incorporating cross-sectional dependence and smooth breaks in testing the Granger causality. Our empirical results have important policy implications for the regional governments in China conducting tourism policy to sustain its regional economic growth.
Saving the Environment in Emerging Markets: The Synergistic Roles of Corporate Ownership Structure, Financing Strategy, and Innovation Capacity
(Wiley, 2025) Ning, Wu; Saeed, Ummar Faruk; Kongkuah, Maxwell
As global environmental challenges intensify and stakeholder pressure mounts, the imperative for companies, particularly in emerging markets, to adopt sustainable practices has become increasingly critical. Addressing a gap in the literature, this study examines the impact of ownership structure (OS) and financing strategy (FS) on environmental footprint disclosure (EFD) among energy sector firms in the Middle East and North Africa (MENA) region, while also considering the moderating role of innovation capacity. Drawing on the resource-based view, signaling, and stakeholder theories, this study analyzes panel data from 384 firms spanning 2010 to 2023. To address potential endogeneity issues, the study employs the difference GMM modeling to mititgate endogeneity issues. Additionally, the MMQR approach is applied to capture heterogeneous effects across varying levels of EFD practices. The findings reveal that concentrated and state ownership significantly enhance EFD, while managerial ownership exerts a negative influence. Firms relying on equity financing demonstrate higher EFD levels compared to those relying on debt. Moreover, innovation capacity not only directly impacts EFD but also amplifies the influence of OS and FS on EFD. Notably, the findings remain robust after employing various econometric techniques, including DiD, 2SLS, DCCE, and PSM. These results suggest that encouraging concentrated and state ownership, alongside equity financing, can drive improved environmental transparency within MENA firms. This study underscores the strategic role of innovation in strengthening EFD, offering valuable guidance for policymakers and industry leaders on ownership and financing decisions to foster sustainable development and enhance environmental responsibility.
AI voice journaling for future language teachers: A path to well-being through reflective practices
(Wiley, 2025) Demir, Bora; Ozdemir, Duygu
This study aimed to explore the perceived impact of using an AI-powered voice journaling app in overcoming the challenges and stressors encountered by senior students enrolled in teaching practicum at an English Language Teaching Bachelor's programme. The main objective of this study is to examine the perceived effect of an AI-powered audio diary app known as the 'Audio Diary' on the general well-being of prospective English language teachers. The study employed a qualitative methodology focusing on the themes created by the extensive data provided by the pre-service English teachers. Through the Audio Diary app, eight volunteer prospective English language teachers documented their daily and professional experiences, emotional states and encountered challenges over the period of 4 weeks. We collected data through the app in order to understand the participants' reflections about their daily and professional experiences. Participant entries and AI-generated output were stored by the app and used for content analysis. Participants characterised the AI-powered Audio Diary app as a helpful tool for reflecting on their personal and professional well-being, according to thematic analysis results. Furthermore, it made it easier for them to communicate and comprehend more deeply, and it gave them insightful information about their own experiences throughout the study. Additionally, the app's AI-categorised feedback assisted users in recognising trends and areas where their teaching methods needed to be improved. It demonstrates, for instance, how AI-powered apps can be used to promote the well-being and reflective practice of pre-service teachers in learning environments.
Identifying early left atrial dysfunction in individuals with obstructive sleep apnea: The role of the morphology-voltage-P wave duration electrocardiography score
(Lithographia, 2024) Kucuk, U.; Mutlu, P.; Mirici, A.; Ozpinar, U.; Ozpinar, Sb
Background: Obstructive sleep apnea (OSA) can lead to left atrial (LA) dysfunction, which increases the risk of severe heart problems such as atrial fibrillation and heart failure. Early detection of LA dysfunction is essential to prevent these complications. We investigated whether the new morphology-voltage-P wave duration electrocardiography (MVP ECG) level could effectively identify early-stage LA functional abnormality in OSA individuals, as current diagnostic techniques have limitations. Methods: We studied a sample of 120 OSA patients using speckle-tracking echocardiography to assess LA function. After the echocardiography exam, we divided these individuals into two groups: those with regular LA and those with impaired LA functions. Our main measure of LA function was peak atrial longitudinal strain (PALS). Results: We found significant differences in PALS values between groups (p <0.001) despite having an equivalent LA size, suggesting occult LA dysfunction in OSA patients. The MVP ECG score proved effective in identifying LA dysfunction caused by changes in atrial structure (sensitivity: 89 %, specificity: 63 %, AUC: 0.862). Conclusions: The MVP ECG score is a promising non-invasive method to detect early atrial changes in OSA patients. Using this score in regular medical care could help physicians intervene earlier, potentially reducing the risk of heart problems in these high-risk individuals.
Comparison of Bicortical Headless Cannulated Screw Fixations, Tension Band Fixations, and Kirschner Wire Fixations of a Jones Fracture A Biomechanical Study
(Amer Podiatric Med Assoc, 2024) Yilmaz, Onur; Mutlu, Ibrahim; Kuru, Tolgahan; Bilge, Ali; Gungor, Berna; Kizilay, Hasan; Olcar, Haci
Background: The aim of study was to biomechanically compare the fixation of Jones fracture using headless cannulated screw, tension band, and two Kirschner wires.' Methods: A total of 60 fourth-generation, fifth metatarsal synthetic bone models were divided into three groups according to the fixation techniques. A vertical load, oriented from plantar to dorsal and lateral to medial, was applied to the metatarsal specimen that were potted with molding material. The stiffness and fatigue values were compared between the three fixation groups. Results: In the plantar to dorsal load test, the stiffness values were found to be significantly higher in Group 1 compared to the other groups (P = .034, P = .013). No significant difference was found in the analysis in terms of fatigue values in plantar to dorsal load testing (P = .348, P = .416). No significant difference was found between compression screw and tension band groups in lateral to medial loading test, in terms of stiffness and fatigue values (P = .096, P = .762). However, the stiffness values and fatigue values of these two groups were found to be statistically significantly higher than the Kirschner wire group (P = .003, P = .002, P = .016, P = .023). Conclusions: The result of this study showed that the bicortical fixation of headless compression screw provides a more stable fixation than other fixation methods, especially in plantar to dorsal loading. (J Am Podiatr Med Assoc 114(6), 2024; doi:10.7547/22-201)
The Strategic Role of Circular Economy Innovations and Stakeholder Engagement in Advancing Responsible Production and Consumption
(Wiley, 2025) KaoDui, Li; Kongkuah, Maxwell
As the urgency of global sustainability goals intensifies, achieving responsible production and consumption (RPC) has become a critical priority, especially in emerging markets where economic growth must be balanced with environmental stewardship. Businesses play a pivotal role in advancing sustainability, and understanding how governance practices influence RPC is essential for aligning corporate strategies with global objectives. This study investigates how circular economy innovations and stakeholder engagement moderate the link between indigenous directors and RPC. Using secondary data from 439 manufacturing firms across MENA countries between 2012 and 2022, we employed the method of moments quantile regression (MMQR) and fixed effects estimations, addressing endogeneity through GMM modeling and propensity score matching techniques. Our findings demonstrate that indigenous directors significantly enhance RPC across all quantiles. Additionally, circular economy innovations not only advance RPC but also amplify the positive effects of indigenous directors on sustainable practices. Stakeholder engagement further strengthens this relationship, particularly in higher quantiles, underscoring the importance of inclusive governance for achieving sustainability goals. These insights provide actionable implications for business leaders and policymakers, particularly in the MENA region, by emphasizing the strategic integration of Indigenous leadership and circular economy innovations into corporate governance. This study offers a framework for aligning business strategies with global sustainability objectives, notably SDG 12 while also contributing to the literature on strategic management and sustainability. By highlighting the role of Indigenous leadership in driving sustainable practices, this research provides valuable guidance for firms and policymakers seeking to advance environmental sustainability in emerging market economies.
Predicting the Altruism of Counsellor Candidates in Terms of Cultural Sensitivity, Social Desirability and Emotional İntelligence
(Wiley, 2025) Sakar, Gozde; Zeren, Serife Gonca
IntroductionAltruism, which is the subject of this research, generally means helping someone else without expecting anything in return. Counsellors assist other people as part of their jobs. This study examined the altruism of counsellor candidates in the context of cultural sensitivity, social desirability and emotional intelligence.MethodThe research included a total of 542 undergraduate students, 416 women and 126 men, studying in the Guidance and Psychological Counselling Department at foundation and state universities in Istanbul. The data for the study were collected with the Altruism Scale, Intercultural Sensitivity Scale, Good Impression Scale and Emotional Intelligence Trait Scale-Short Form. Multiple linear regression analysis, hierarchical regression analysis and structural equation modelling mediation analysis were used to analyse the data.ResultsThe research concluded that the variables of cultural sensitivity, social desirability and emotional intelligence predicted the altruism of counsellor candidates. It was understood that the variance in altruism was explained most by cultural sensitivity, followed by social desirability and least by emotional intelligence. Psychological and social factors, particularly cultural sensitivity and social desirability, were found to be more effective than demographic variables in explaining altruism. Additionally, the SEM analysis indicated that cultural sensitivity mediated the relationship between emotional intelligence and altruism, while social desirability had a strong direct effect on altruism.ConclusionIn line with the results of research, it is recommended to increase the number and amount of content of courses in which students will have more comprehensive knowledge about cultural infrastructure related to their awareness, empathy levels, realistic perspectives and interactions with different individuals. It is suggested that social responsibility projects, club activities and Erasmus opportunities that will support the aims mentioned, in addition to course achievements, are supported by both lecturers and the university administration.
Life in Extreme Conditions: Diet and Condition of the Extremophile Fish Aphanius almiriensis (Teleostei: Cyprinodontiformes) in a Thermal Rheocrene Spring
(Wiley, 2025) Sac, Gulsah; Ozulug, Oya; Agdamar, Sevan; Inci, Harun; Yurekli, Ozgun Deniz; Ozulug, Mufit
This study aims to understand the bioecological traits of an extremophile fish, Aphanius almiriensis, in order to explore how it survives and colonizes extreme habitat conditions. To achieve this, the bioecological characteristics-condition, diet, and feeding strategy-of A. almiriensis inhabiting the Tuzla thermal spring, which is characterized by extreme habitat conditions in terms of physicochemical water parameters, were studied. Among the physicochemical parameters measured, salinity and temperature were remarkably high, ranging from 23.7 degrees C (in winter) to 42.7 degrees C (in summer) and from 47.7 ppt (in autumn) to 60.7 ppt (in winter). A total of 248 fish individuals were collected from the thermal spring, and the diet analyzed seasonally consisted of 17 different food items, and their importance values (MI% and IRI%) varied seasonally. According to the F%, IRI%, and MI% values, the population fed mainly on Diatom, Cyanobacteria, and Diptera, resulting in niche breadth with low values ranging from 0.25 to 0.54. The extreme conditions of the thermal spring indicated that the environment was poor in terms of macroinvertebrate diversity (six taxa), and fish showed food selectivity (E) for Chironomidae and Ceratopogonidae in winter, spring, and summer and for Ephydridae in autumn (E > 0; positive selectivity). Seasonally influenced fish condition was represented by high values in summer (K = 1.43 +/- 0.14) and was positively correlated with both water temperature and the increasing importance of the genus Phormidium in its diet. This study provides the first comprehensive insight into the seasonal diet and condition of A. almiriensis, shedding light on its survival strategies in harsh ecological conditions.
Unveiling Bone and Dental Regeneration Potential of Quince Seed Mucilage-Nanohydroxyapatite Scaffolds in Rabbit Mandibles
(Wiley, 2025) Genc, Cigdem Cetin; Yilmaz-Dagdeviren, Hilal Deniz; Deniz, Yesim; Derkus, Burak; Degirmenci, Alpin; Arslan, Yavuz Emre
Donor-side morbidity of autografting for maxillofacial region defect regeneration has directed attention to bioengineered scaffolds. Composite scaffolds that mimic the bone extracellular matrix (ECM) are the potential candidates for defect reconstruction. Herein, a plant-based regenerative hydrogel, quince seed mucilage (QSM), was enriched with the nanohydroxyapatite (nHAp) particles to construct composite scaffolds (QSM/nHAp). The emerging scaffold is able to induce cellular spheroid formation and regenerate the critical-sized bilateral mandibular defects in rabbits. The macroscopic observations, histochemical (HC) and immunohistochemical (IHC) stainings, mu-computer tomography (CT) scanning, quantitative real time-polymerase chain reaction (qRT-PCR) analyses, and scanning electron microscopy (SEM) imaging revealed that all QSM/nHAp scaffolds were swelled with host blood, filled the whole cavity, and sustained cellular infiltration without adverse reactions. The gradual biodegradation profile of the scaffolds improved bone regeneration by releasing nHAp particles from the scaffold. Strikingly, co-development of dental and bone regeneration was observed for all QSM/nHAp groups beginning after day 21. Moreover, QSM/nHAp scaffolds induced expression (> 2-fold) of bone and dental-related gene and protein expressions at the grafted area and sustained a proper platform for maxillofacial remodeling. Therefore, we strongly believe that such biocompatible plant-based constructs, compared with conventional medical devices used in maxillofacial surgery, could support and induce simultaneous bone and dental regeneration due to the intrinsic dynamics of the material.
Feasibility and performance evaluation of randomly oriented strand recycled composite skins in sandwich structures: A green cost-effective solution for aerospace secondary load-bearing applications
(Wiley, 2025) Ozbek, Yagiz; Al-Nadhari, Abdulrahman; Elmas, Sinem; Eskizeybek, Volkan; Yildiz, Mehmet; Sas, Hatice S.
Despite the advantages of recycled randomly oriented strand (ROS) composites over recycled grinded ones, the warpage issue hinders their adaptation in the industry due to tolerance requirements. To address this challenge, ROS composites are incorporated into secondary bonded sandwich structures such that the core material ensures the straightness of the ROS composite skins. Additionally, atmospheric plasma activation (APA) is utilized to enhance the skin/core bonding to prevent skin separation under loading. The ROS composite skins are manufactured via vacuum-assisted hot press to achieve a cost-effective aerospace-grade quality. The structural integrity of the sandwich structure is assessed through flatwise tensile and edgewise compression tests, while the mechanical and thermomechanical performance is evaluated using flexural, impact, and dynamic mechanical analysis (DMA) tests. The flatwise tensile and edgewise compression tests confirm that APA effectively prevents core detachment, as evidenced by an average tensile strength of 2.28 MPa and an average compressive strength of 171.7 MPa. Moreover, the flexural and impact tests show that no premature skin failure occurs, supported by an average facing strength of 59.23 MPa in flexural testing and an average impact energy of 49.96 kJ/m(2). The DMA test indicates that most of the stiffness loss is due to the core material. This comprehensive analysis highlights recycled ROS composites as a sustainable and cost-effective alternative for quasi-isotropic skins in aerospace secondary load-bearing sandwich structures such as floors, doors, engine cowls, and spoilers.
A dual approach using response surface methodology and machine learning for optimization and enhancement of microalgae-based municipal wastewater treatment
(Wiley, 2025) Kayan, Iremsu; Oz, Nilgun Ayman
BACKGROUNDMunicipal wastewater comprises both organic and inorganic contaminants. Especially in rural areas, conventional municipal treatment plants primarily focus on carbon removal; therefore, nutrient removal should be prioritized for preventing environmental pollution. Mixotrophic microalgae such as Nannochloropsis sp. have significant potential for both carbon and nutrient removal. However, microalgae-based wastewater systems can be affected by many parameters and, using response surface methodology and decision tree, a machine learning model can help to determine the optimal conditions for the systems to operate more efficiently. RESULTSThe optimal removal conditions were determined by response surface methodology to be a light period of 21 h at an intensity of 8000 lx and a temperature value of 30 degrees C. Under these optimal conditions, the respective removal efficiency for chemical oxygen demand, total organic carbon, total Kjeldahl nitrogen, and orthophosphate was 53%, 34%, 87%, and 70%, respectively. Chlorophyll-a concentration increased by as much as 49%. Real municipal wastewater was used instead of synthetic wastewater, yielding closer approximations to real situations. CONCLUSIONThe present study has underscored innovative, data-driven approaches as core in ensuring sustainable wastewater management and sets a useful framework for future research, which could be done with the aim of refining the methods to enhance efficiency in treatment. (c) 2025 The Author(s). Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).
Moxifloxacin-Impregnated Contact Lenses for Treatment of Keratitis in Rabbit Eyes
(Wiley, 2025) Erdogan, Hakika; Gungor, Buket; Suner, Selin S.; Silan, Coskun; Saraydin, Serpil U.; Saraydin, Dursun; Ayyala, Ramesh S.
Moxifloxacin (MOX) was loaded into commercial contact lenses (CLs) via supercritical carbon dioxide (ScCO2) to attain MOX-impregnated CL for keratitis treatment. This study aimed to investigate Pseudomonas keratitis treatment with MOX-impregnated CL compared to the traditional eyedrop administration. MOX impregnation was accomplished employing optimum parameters of 2.5 h drug exposure time, 25 MPa pressure, and 313 K for ScCO2 conditions using ethanol co-solvent rendering sustainable delivery, up to 7 days at effective dosage formulation. The MOX-impregnated CL was found to be safe with no significant toxicity on fibroblast cells after 5 days of contact time. Bacterial viability in vivo keratitis treatment in rabbit eyes was significantly decreased to 10(2) from 10(9) CFU/cornea for MOX-impregnated CL treatment, almost similar to exhaustive conventional 0.5% MOX eye drop treatments. The MOX-impregnated CL treatment revealed no conjunctival hyperemia, edema, or secretion for all eyes in the relevant group, and transparent cornea with no keratitis focus was obtained for two of the eyes (n = 6). The normal histological structure was seen with MOX-impregnated CL treatment on healthy eyes. Moreover, polymorphonuclear cell infiltration observed in keratitis eyes without any treatment was significantly decreased to a few polymorphonuclear cells in the groups treated with MOX eyedrops and MOX-impregnated CL.
Investigation of Human Hair by Laser-Induced Breakdown Spectroscopy: Qualitative and Quantitative Analysis of Content Element in Human Hair
(Wiley, 2025) Arbi, Ines; Yumun, Gunduz; Sezgin, Nursel
Human hair is a significant biological sample in forensic science, biomedical research, and the cosmetic industry, with the presence of essential nutrients like zinc, copper, and silicon being indicative of health. This study aimed to investigate the elemental composition of human hair using Laser-Induced Breakdown Spectroscopy (LIBS) to assess differences across age groups. Nine volunteers provided hair samples, which were analyzed using the Foster + Freeman ECCO2 LIBS system. Quantitative analysis of elemental concentrations was performed, and elemental ratios, such as Mg/Ca, Mg/Si, Mg/Fe, and Fe/Mn, were calculated to compare the samples. Results demonstrated that LIBS is a fast, accurate, and non-destructive method for detecting and quantifying mineral elements in human hair. The study highlights age-related differences in elemental concentrations, offering insights into the use of hair analysis for monitoring nutritional and health status. LIBS could be a promising tool for further studies in clinical and forensic applications.
Neuroanatomical Correlates of Memory Strategies in Rats
(Wiley, 2025) Balci, Aysu; Cankurtaran, Buse Pinar; Akyel, Aybuke; Arikan, Kutluk Bilge; Unal, Bengi; Unal, Cagri Temucin
Navigation incorporates a continuum of strategies, where the allocentric strategy relies on relationships between environmental landmarks resulting in a cognitive map, and the egocentric strategy revolves around the body position and stimulus response chains with the body as a reference. Although multiple brain regions contribute to navigation, the hippocampus dominates allocentric navigation, whereas the striatum is key for egocentric navigation. Neuromodulators, such as dopamine and acetylcholine, regulate both the hippocampus and striatum to influence behavior, yet their influence on navigational strategy has not been determined. Interindividual differences in strategy preference are known to exist. Building on these pre-existing interindividual differences, this study explored the neuroanatomical underpinnings on navigational strategy variations in rats through a dual-solution T-maze and immunocytochemistry. Surprisingly, interindividual variations eluded explanation through the density of cholinergic neurons supplying acetylcholine to the hippocampus and striatum. Similarly, the soma morphologies of these neurons exhibited no discernible differences. Dopaminergic cell densities in the ventral tegmental area (VTA), projecting to the hippocampus, and substantia nigra pars compacta (SNpc), projecting to the striatum, failed to account for individual variations as well. Nevertheless, allocentric rats displayed higher VTA/SNpc dopamine neuron fusiformity indexes, potentially contributing to computational distinctions underlying interindividual variations in navigation strategies. This study delves into potential explanations and charts promising avenues for future research. A graphical abstract summarizing the main findings of this study is provided.
The Effects of Curcuminoids Supplementation on Serum Adipokines: An Umbrella Review of Meta-Analyses of Randomized Controlled Trials
(Wiley, 2025) Bahrami, Leila Sadat; Rahnama, Iman; Chambari, Mahla; Norouzy, Abdolreza; Karav, Sercan; Arabi, Seyyed Mostafa; Sahebkar, Amirhossein
This umbrella review of randomized clinical trials aims to provide a unique and detailed understanding of curcumin's effects on adipokines, adding a novel perspective to the existing body of research. We carried out a thorough search of international databases up to April 2024, including MEDLINE, SciVerse Scopus, and Clarivate Analytics Web of Science. A random-effects model was utilized to evaluate the impact of curcuminoid on adipokines. The umbrella review incorporated meta-analyses that examined the effects of curcuminoid supplementation on adipokines, presenting associated effect sizes (ES) and confidence intervals (CI). We applied the GRADE and AMSTAR (A Tool for Assessing the Risk of Bias in Systematic Reviews system) to assess the certainty of the evidence and the quality of the systematic reviews. Our analysis of one meta-analysis, including 14 RCTs plus 1 RCT not included in meta-analyses, revealed significant and impactful findings. We found a substantial increase in serum adiponectin levels with curcuminoid supplementation, indicating a positive effect (SMD: 0.9; 95% CI, 0.4 to 1.3, p < 0.001; I-2 = 92.2%). However, we did not observe a significant impact on serum leptin. The GRADE assessment supports the effect of curcuminoids on adiponectin with moderate evidence, while the impact on leptin was supported by low evidence. Curcuminoid supplementation significantly increases serum adiponectin levels with moderate-quality evidence and has no significant impact on serum leptin. This provides evidence as to the safety and effectiveness of curcuminoids in enhancing adiponectin without adverse effects, reassuring the audience about their potential in adipokine research.

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