Fabrication of Electrochemical Immunosensor for Detection of Interleukin 8 Biomarker via Layer-by-layer Self-assembly Process on Cost-effective Fluorine Tin Oxide Electrode

dc.authorid0000-0003-3042-1087en_US
dc.authorscopusid6506764918en_US
dc.authorwosidAAY-1439-2021en_US
dc.contributor.authorAydın, Elif Burcu
dc.contributor.authorSezgintürk, Mustafa Kemal
dc.date.accessioned2022-08-11T12:31:24Z
dc.date.available2022-08-11T12:31:24Z
dc.date.issued2021en_US
dc.departmentFakülteler, Mühendislik Fakültesi, Biyomühendislik Bölümü
dc.description.abstractA highly sensitive impedimetric immunosensor for the determination of interleukin 8 (IL 8) cancer biomarker was fabricated via simple fabrication process. A silane agent with isocyanate groups, 3-(triethoxysilyl)propyl isocyanate (IPTES), were utilized for binding of IL 8 antigen specific antibodies and self-assembled on the fluorine tin oxide (FTO) substrate with a standard silanization chemistry. Under optimum experimental conditions, the designed immunosensor had a wide linear detection range of 0.02-4 pg/mL, a low limit of detection of 11.9 fg/mL and a high sensitivity of 4.42 k omega pg(-1) mL cm(-2). The designed biosensor displayed high reproducibility and repeatability, good selectivity against interference biomarkers.en_US
dc.identifier.citationAydın, E. B., & Sezgintürk, M. K. (2021). Fabrication of Electrochemical Immunosensor for Detection of Interleukin 8 Biomarker via Layer‐by‐layer Self‐assembly Process on Cost‐effective Fluorine Tin Oxide Electrode. Electroanalysis, 33(6), 1596–1605. https://doi.org/10.1002/elan.202060603 ‌en_US
dc.identifier.doi10.1002/elan.202060603
dc.identifier.endpage1605en_US
dc.identifier.issn1040-0397
dc.identifier.issn1521-4109
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85102957235
dc.identifier.startpage1596en_US
dc.identifier.urihttps://doi.org/10.1002/elan.202060603
dc.identifier.urihttps://hdl.handle.net/20.500.12428/3668
dc.identifier.volume33en_US
dc.identifier.wosWOS:000631854300001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorSezgintürk, Mustafa Kemal
dc.language.isoen
dc.publisherWileyen_US
dc.relation.ispartofElectroanalysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectElectrochemical Analysisen_US
dc.subjectChemicals and Materialsen_US
dc.subjectReal Sample Analysisen_US
dc.subjectChemical Characterizationen_US
dc.subjectInterleukinen_US
dc.subjectFluorine tin oxide3en_US
dc.subject(triethoxysilyl)Propyl Isocyanateen_US
dc.subjectDisposable Electrodeen_US
dc.titleFabrication of Electrochemical Immunosensor for Detection of Interleukin 8 Biomarker via Layer-by-layer Self-assembly Process on Cost-effective Fluorine Tin Oxide Electrode
dc.typeArticle

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