Determination of antioxidant activity and DNA damage protection of marchantia polymorpha L.

Basit Öğe Kaydı
dc.authorid0000-0002-3554-1881en_US
dc.authorid0000-0002-2347-8344en_US
dc.authorscopusid55665644200en_US
dc.authorscopusid55858603800en_US
dc.authorwosidCAI-2940-2022en_US
dc.authorwosidU-4529-2018en_US
dc.contributor.authorYayıntaş, Özlem Tonguç
dc.contributor.authorDemir, Neslihan
dc.date.accessioned2022-07-07T07:20:42Z
dc.date.available2022-07-07T07:20:42Z
dc.date.issued2021en_US
dc.departmentFakülteler, Fen Fakültesi, Biyoloji Bölümü
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü
dc.description.abstractIn this study, the potential biological effects of Maarchantia polymorpha (Bryophyte) from Mount Ida (Crinakkale/Turkey) were investigated. M. polymorpha was extracted using the Soxhlet apparatus with several organic solvents (hexane, chloroform, acetone, ethanol, methanol, and aqueous) at different concentrations. Phytochemical screening tests are done to detect certain compounds. The total phenolic content was determined with the Folin-Ciocalteau method. Total flavonoid content was determined with AlCl3 method. Ethanolic extract was found to have higher total phenolic and flavonoid contents (18.24 GAE/g extract and 23.06 mgQE/g extract, respectively) than the other extracts. Antioxidant activities were examined by DPPH and ABTS radical scavenging assays. If polymorpha extracts showed that dose-dependent percent inhibition. The aqueous extract had the highest DPPH percentage of scavenging activity (70.87% at a concentration of 80 mu g/mL) followed by methanolic extract (68.59%). For ABTS radical scavenging activity, methanol extract showed the highest inhibition (73.12%) than other extracts. Various extracts were able to protect plasmid DNA by oxidative damage. The present study showed that polvmorpha could be a potential source of antioxidants and protective effects against plasmid DNA.en_US
dc.identifier.citationTonguc Yayıntaş, O., Demir, N. (2021). Determination of antioxidant activity and DNA damage protection of marchantia polymorpha L. Fresenius Environmental Bulletin, 30(4), 3420-3426.en_US
dc.identifier.endpage3426en_US
dc.identifier.issn1018-4619
dc.identifier.issn1610-2304
dc.identifier.issue4en_US
dc.identifier.startpage3420en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12428/3614
dc.identifier.volume30en_US
dc.identifier.wosWOS:000658171700038
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.institutionauthorYayıntaş, Özlem Tonguç
dc.institutionauthorDemir, Neslihan
dc.language.isoen
dc.publisherParlar Scientific Publicationsen_US
dc.relation.ispartofFresenius Environmental Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntioxidant activityen_US
dc.subjectDNA protectionen_US
dc.subjectMarchantia polymorphaen_US
dc.subjectIda Mountain (Canakkale, Turkey)en_US
dc.titleDetermination of antioxidant activity and DNA damage protection of marchantia polymorpha L.
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Ozlem_Tonguc_Yayintas_Makale.pdf
Boyut:
444.88 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Araştırma Makalesi
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Biyoloji Bölümü Koleksiyonu
Moleküler Biyoloji ve Genetik Bölümü Koleksiyonu
Temel Tıp Bilimleri Bölümü Koleksiyonu