New fully automated software for assessment of brachial artery flow-mediated dilation with advantages of continuous measurement

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dc.authoridBayram, Vildan / 0000-0002-8343-1126
dc.authoridKırılmaz, Bahadır / 0000-0002-5929-1426
dc.contributor.authorErcan, Ertugrul
dc.contributor.authorKırılmaz, Bahadır
dc.contributor.authorKahraman, İsmail
dc.contributor.authorBayram, Vildan
dc.contributor.authorDoğan, Hüseyin
dc.date.accessioned2025-01-27T20:24:58Z
dc.date.available2025-01-27T20:24:58Z
dc.date.issued2012
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: Flow-mediated dilation (FMD) is used to evaluate endothelial functions. Computer-assisted analysis utilizing edge detection permits continuous measurements along the vessel wall. We have developed a new fully automated software program to allow accurate and reproducible measurement. Methods: FMD has been measured and analyzed in 18 coronary artery disease (CAD) patients and 17 controls both by manually and by the software developed (computer supported) methods. The agreement between methods was assessed by Bland-Altman analysis. Results: The mean age, body mass index and cardiovascular risk factors were higher in CAD group. Automated FMD% measurement for the control subjects was 18.3+/-8.5 and 6.8+/-6.5 for the CAD group (p=0.0001). The intraobserver and interobserver correlation for automated measurement was high (r=0.974, r=0.981, r=0.937, r=0.918, respectively). Manual FMD% at 60th second was correlated with automated FMD % (r=0.471, p=0.004). Conclusions: The new fully automated software (c) can be used to precise measurement of FMD with low intra-and interobserver variability than manual assessment. (Anadolu Kardiyol Derg 2012; 12: 553-9)
dc.identifier.doi10.5152/akd.2012.190
dc.identifier.endpage559
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue7
dc.identifier.pmid22877899
dc.identifier.scopus2-s2.0-84868271075
dc.identifier.scopusqualityN/A
dc.identifier.startpage553
dc.identifier.trdizinid145236
dc.identifier.urihttps://doi.org/10.5152/akd.2012.190
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22399
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/145236
dc.identifier.volume12
dc.identifier.wosWOS:000312740700011
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherTurkish Soc Cardiology
dc.relation.ispartofAnatolian Journal of Cardiology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectFlow mediated dilation
dc.subjectendothelial function
dc.subjectreliability and validity
dc.titleNew fully automated software for assessment of brachial artery flow-mediated dilation with advantages of continuous measurement
dc.title.alternativeBrakiyal arterde akıma bağlı vazodilatasyon değerlendirilmesi için sürekli ölçüm yapabilen yeni bir yazılım yöntemi
dc.typeArticle

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