New fully automated software for assessment of brachial artery flow-mediated dilation with advantages of continuous measurement
Yükleniyor...
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turkish Soc Cardiology
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: Flow-mediated dilation (FMD) is used to evaluate endothelial functions. Computer-assisted analysis utilizing edge detection permits continuous measurements along the vessel wall. We have developed a new fully automated software program to allow accurate and reproducible measurement. Methods: FMD has been measured and analyzed in 18 coronary artery disease (CAD) patients and 17 controls both by manually and by the software developed (computer supported) methods. The agreement between methods was assessed by Bland-Altman analysis. Results: The mean age, body mass index and cardiovascular risk factors were higher in CAD group. Automated FMD% measurement for the control subjects was 18.3+/-8.5 and 6.8+/-6.5 for the CAD group (p=0.0001). The intraobserver and interobserver correlation for automated measurement was high (r=0.974, r=0.981, r=0.937, r=0.918, respectively). Manual FMD% at 60th second was correlated with automated FMD % (r=0.471, p=0.004). Conclusions: The new fully automated software (c) can be used to precise measurement of FMD with low intra-and interobserver variability than manual assessment. (Anadolu Kardiyol Derg 2012; 12: 553-9)
Açıklama
Anahtar Kelimeler
Flow mediated dilation, endothelial function, reliability and validity
Kaynak
Anatolian Journal of Cardiology
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
12
Sayı
7
