Phosphazene-based nanostructures modified with gold nanoparticles as drug and gene carrier materials with antibacterial and antifungal properties

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dc.authorid-en_US
dc.authorid0000-0001-6589-9844en_US
dc.authorscopusid57941577000en_US
dc.authorscopusid23973597600en_US
dc.authorwosidGZL-1463-2022en_US
dc.authorwosid-en_US
dc.contributor.authorÖzsoy, Fatma
dc.contributor.authorÖzay, Özgür
dc.date.accessioned2024-01-24T13:31:36Z
dc.date.available2024-01-24T13:31:36Z
dc.date.issued2023en_US
dc.departmentEnstitüler, Lisansüstü Eğitim Enstitüsü, Biyomühendislik Ana Bilim Dalı
dc.departmentFakülteler, Mühendislik Fakültesi, Biyomühendislik Bölümü
dc.description.abstractIn this study, monodisperse spherical particles were synthesized by using hexachlorocyclotriphosphazene (HCCP) and 1-(2-Aminoethyl) piperazine (AEP) by the polycondensation reaction. Then, the surfaces of the synthesized nanospheres were functionalized with gold nanoparticles. Phz-AEP nanospheres and phz-AEP@Au nanocomposite were characterized by various methods. Drug release studies for the synthesized phz-AEP and phz-AEP@Au nanospheres were performed using a ribonucleic acid (RNA) and sodium diclofenac (NaDc). As a result of the release studies, the drug release kinetics of the nanospheres were investigated. Additionally, the antibacterial and antifungal effects of the synthesized phz-AEP and phz-AEP@Au nanocomposite spheres were tested.en_US
dc.identifier.citationÖzsoy, F., & Özay, Ö. (2023). Phosphazene-based nanostructures modified with gold nanoparticles as drug and gene carrier materials with antibacterial and antifungal properties. International Journal of Polymeric Materials and Polymeric Biomaterials, 1–12. https://doi.org/10.1080/00914037.2022.2163642en_US
dc.identifier.doi10.1080/00914037.2022.2163642
dc.identifier.endpage12en_US
dc.identifier.issn0091-4037
dc.identifier.issn1563-535X
dc.identifier.scopus2-s2.0-85147013389
dc.identifier.startpage1en_US
dc.identifier.urihttps://doi.org/10.1080/00914037.2022.2163642
dc.identifier.urihttps://hdl.handle.net/20.500.12428/5397
dc.identifier.wosWOS:000915671600001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorÖzsoy, Fatma
dc.institutionauthorÖzay, Özgür
dc.language.isoen
dc.publisherTaylor and Francis Ltd.en_US
dc.relation.ispartofInternational Journal of Polymeric Materials and Polymeric Biomaterialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDrug releaseen_US
dc.subjectFunctional materialen_US
dc.subjectGold nanoparticleen_US
dc.subjectPhosphazeneen_US
dc.subjectRNAen_US
dc.titlePhosphazene-based nanostructures modified with gold nanoparticles as drug and gene carrier materials with antibacterial and antifungal properties
dc.typeArticle

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