Lab-on-a-chip systems for cancer biomarker diagnosis

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dc.authorid0000-0002-3735-1213en_US
dc.authorid0000-0003-4296-2657en_US
dc.authorid-en_US
dc.authorid0000-0003-3042-1087en_US
dc.authorscopusid55838812200en_US
dc.authorscopusid57212611236en_US
dc.authorscopusid57219614075en_US
dc.authorscopusid6506764918en_US
dc.authorwosidAAY-6055-2021en_US
dc.authorwosidHDN-2668-2022en_US
dc.authorwosidGWR-0139-2022en_US
dc.authorwosidAAY-1439-2021en_US
dc.contributor.authorÖzyurt, Canan
dc.contributor.authorUludağ, İnci
dc.contributor.authorİnce, Bahar
dc.contributor.authorSezgintürk, Mustafa Kemal
dc.date.accessioned2023-10-30T07:27:28Z
dc.date.available2023-10-30T07:27:28Z
dc.date.issued2023en_US
dc.departmentFakülteler, Mühendislik Fakültesi, Biyomühendislik Bölümü
dc.departmentMeslek Yüksekokulları, Lapseki Meslek Yüksekokulu, Kimya ve Kimyasal İşleme Teknolojileri Bölümü
dc.description.abstractLab-on-a-chip (LOC) or micro total analysis system is one of the microfluidic technologies defined as the adaptation, miniaturization, integration, and automation of analytical laboratory procedures into a single instrument or “chip”. In this article, we review developments over the past five years in the application of LOC biosensors for the detection of different types of cancer. Microfluidics encompasses chemistry and biotechnology skills and has revolutionized healthcare diagnosis. Superior to traditional cell culture or animal models, microfluidic technology has made it possible to reconstruct functional units of organs on chips to study human diseases such as cancer. LOCs have found numerous biomedical applications over the past five years, including integrated bioassays, cell analysis, metabolomics, drug discovery and delivery systems, tissue and organ physiology and disease modeling, and personalized medicine. This review provides an overview of the latest developments in microfluidic-based cancer research, with pros, cons, and prospects.en_US
dc.identifier.citationÖzyurt, C., Uludağ, İ., İnce, B., & Sezgintürk, M. K. (2023). Lab-on-a-chip systems for cancer biomarker diagnosis. Journal of Pharmaceutical and Biomedical Analysis, 226, 115266. https://doi.org/10.1016/j.jpba.2023.115266en_US
dc.identifier.doi10.1016/j.jpba.2023.115266
dc.identifier.issn0731-7085
dc.identifier.issn1873-264X
dc.identifier.pmid36706542
dc.identifier.scopus2-s2.0-85146888007
dc.identifier.urihttps://doi.org/10.1016/j.jpba.2023.115266
dc.identifier.urihttps://hdl.handle.net/20.500.12428/4609
dc.identifier.volume226en_US
dc.identifier.wosWOS:000961144300001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzyurt, Canan
dc.institutionauthorUludağ, İnci
dc.institutionauthorİnce, Bahar
dc.institutionauthorSezgintürk, Mustafa Kemal
dc.language.isoen
dc.publisherElsevier B.V.en_US
dc.relation.ispartofJournal of Pharmaceutical and Biomedical Analysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiosensorsen_US
dc.subjectCanceren_US
dc.subjectLab-on-a-chipen_US
dc.subjectMicrofluidic technologyen_US
dc.titleLab-on-a-chip systems for cancer biomarker diagnosis
dc.typeArticle

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