Four Bipolar Cases Treated with Quetiapine During Pregnancy

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dc.contributor.authorDegerli, Hatice Ezgi
dc.contributor.authorAltinbas, Kursat
dc.contributor.authorDeuce, Mehtap
dc.contributor.authorKurt, Erhan
dc.date.accessioned2025-01-27T20:14:47Z
dc.date.available2025-01-27T20:14:47Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBipolar disorder is a disease that typically begins in adolescence and early adulthood, namely during the reproductive period. The treatment of female cases during their reproductive years is very important because of the teratogenic effects of psychotropic drugs. It has been stated that the use of classical antipsychotics during pregnancy was not associated with congenital malformations or low birth weight. While all drugs pass through the placenta, quetiapine shows the lowest degree of placenta transit of all the antipsychotics. Studies with animals have not showed any teratogenic effect. Even though studies with humans are very limited with respect to embryonic/fetal risk assessment, recent studies have shown no increased risk of birth defects in quetiapine exposed babies and when compared to other treatment alternatives, quetiapine can be used safely in pregnancy. In this article, we report that no negative data has been found in terms of teratogenicity or perinatal complications in the cases of four pregnant women being treated with quetiapine in the manic and depressive episodes of bipolar disorder and it is also reported that quetiapine can reliably be used during pregnancy.
dc.identifier.doi10.5455/bcp.20140714030311
dc.identifier.endpage395
dc.identifier.issn1017-7833
dc.identifier.issue4
dc.identifier.scopus2-s2.0-84921471153
dc.identifier.scopusqualityN/A
dc.identifier.startpage391
dc.identifier.trdizinid166585
dc.identifier.urihttps://doi.org/10.5455/bcp.20140714030311
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/166585
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21198
dc.identifier.volume24
dc.identifier.wosWOS:000348334900015
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherKure Iletisim Grubu A S
dc.relation.ispartofKlinik Psikofarmakoloji Bulteni-Bulletin of Clinical Psychopharmacology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectbipolar disorder
dc.subjectpregnancy
dc.subjectquetiapine
dc.titleFour Bipolar Cases Treated with Quetiapine During Pregnancy
dc.title.alternativeGebelik döneminde ketiapin ile tedavi edilen dört bipolar olgu
dc.typeArticle

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