The Relationship of Thyroid Hormone Levels and Motor Symptoms in Parkinson's Disease

Basit Öğe Kaydı
dc.authoridŞahin, Erkan Melih/0000-0003-1520-8464
dc.contributor.authorOcak, Ozgul
dc.contributor.authorŞahin, Erkan Melih
dc.contributor.authorCam, Mustafa
dc.date.accessioned2025-01-27T21:19:31Z
dc.date.available2025-01-27T21:19:31Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim: This study aimed to investigate the relationship between thyroid hormone levels and the motor symptoms of Parkinson's patients. Material and Methods: Neurology clinic logs of the patients diagnosed with Parkinson's disease and whose thyroid function tests were measured between 01.01.2018 and 01.04.2021 were selected. Those with primary thyroid hormone disorder were excluded. Motor symptom stages were determined according to the modified Hoehn and Yahr scale (mHYS) by records. According to the thyroid function test results, whether there was a difference in motor symptoms, duration of the disease, and effects of the drugs were examined. Results: Of the 93 patients included in the study, 53 (57.0%) were male and 40 (43.0%) were female. The median age of the patients was 71 years. The motor symptoms of the patients were classified as stage 1 in 21 (22.6%), stage 1.5 in 18 (19.4%), stage 2 in 29 (31.2%), stage 2.5 in 13 (14.0%), stage 3 in 4 (4.3%), stage 4 in 6 (6.5%), and stage 5 in 2 (2.2%) patients. The median levels of TSH, fT3, and fT4 were 2.075 uIU/ml, 2.925 ng/dl, and 1.235 ng/dl, respectively. There was no significant correlation between the mHYS stages of the patients and TSH (r=-0.148, p=0.164), fT3 (r=-0.073, p=0.623), and fT4 levels (r=0.075, p=0.491). Conclusion: There was no relationship between the severity of motor symptoms and hormone levels in patients with normal thyroid functions. Thyroid dysfunction may mimic many motor findings, but they do not affect the severity of motor findings in Parkinson's patients.
dc.identifier.doi10.18678/dtfd.1068664
dc.identifier.endpage146
dc.identifier.issn1307-671X
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85136274181
dc.identifier.scopusqualityQ3
dc.identifier.startpage142
dc.identifier.trdizinid1115669
dc.identifier.urihttps://doi.org/10.18678/dtfd.1068664
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1115669
dc.identifier.urihttps://hdl.handle.net/20.500.12428/28645
dc.identifier.volume24
dc.identifier.wosWOS:001207163500009
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherDuzce Univ, Fac Medicine
dc.relation.ispartofDuzce Medical Journal
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectParkinson's disease
dc.subjectmotor symptoms
dc.subjectthyroid functions
dc.titleThe Relationship of Thyroid Hormone Levels and Motor Symptoms in Parkinson's Disease
dc.title.alternativeParkinson Hastalığında Motor Semptomların Tiroid Hormon Seviyeleri ile İlişkisi
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu