Preparation of Macroporous Carboxymethyl Cellulose Cryogels and Its Blood Compatibility

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dc.contributor.authorSaniner, Nurettin
dc.contributor.authorSuner, Selin S.
dc.contributor.authorTosunoğlu, Murat
dc.date.accessioned2025-01-27T21:19:26Z
dc.date.available2025-01-27T21:19:26Z
dc.date.issued2020
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractSuperporous Carboxy Methyl Cellulose (CMC) cryogels were synthesized by chemical crosslinking of linear CMC with divinyl sulfone (DVS) with different mole ratios of CMC repeating unit down to 2.5%. The morphology of macroporous CMC cryogels was visualized by optic microscope and scanning electron microscope (SEM) images. The swelling capacity and pore volume of CMC cryogels were found to increase with the decrease in the ratio of crosslinker to CMC, and the highest swelling capacity and pore volume values were 10825 +/- 1799% and 22.1 +/- 0.4 mL/g for 2.5% mole ratio of crosslinked CMC cryogels. The blood compatibility of CMC cryogels revealed that blood cells were destroyed with very low hemolysis ratio of 1.09 +/- 1% and also showed less thrombogenic activity with 80.2 +/- 5.1% blood clotting indexes.
dc.description.sponsorshipScientific Research Commission of Canakkale Onsekiz Mart University, (COMU BAP) [FBA-2016-740]
dc.description.sponsorshipThis work is supported by the Scientific Research Commission of Canakkale Onsekiz Mart University, (COMU BAP, FBA-2016-740).
dc.identifier.doi10.1557/adv.2019.483
dc.identifier.endpage833
dc.identifier.issn2059-8521
dc.identifier.issue16
dc.identifier.scopus2-s2.0-85097881306
dc.identifier.scopusqualityQ3
dc.identifier.startpage825
dc.identifier.urihttps://doi.org/10.1557/adv.2019.483
dc.identifier.urihttps://hdl.handle.net/20.500.12428/28603
dc.identifier.volume5
dc.identifier.wosWOS:000530306700004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherCambridge Univ Press
dc.relation.ispartofMrs Advances
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectmicrostructure
dc.subjectbiomaterial
dc.subjectporosity
dc.titlePreparation of Macroporous Carboxymethyl Cellulose Cryogels and Its Blood Compatibility
dc.typeArticle

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