Anthocyanins: Metabolic Digestion, Bioavailability, Therapeutic Effects, Current Pharmaceutical/Industrial Use, and Innovation Potential

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dc.authorid0000-0001-9705-6921en_US
dc.authorid0000-0003-1784-9134en_US
dc.authorid0000-0001-5746-8921en_US
dc.authorid0000-0002-8102-0577en_US
dc.authorscopusid54792612800en_US
dc.authorscopusid50462118800en_US
dc.authorscopusid55389584500en_US
dc.authorscopusid57191202269en_US
dc.authorwosid-en_US
dc.authorwosidA-4827-2016en_US
dc.authorwosid-en_US
dc.authorwosidE-4827-2012en_US
dc.contributor.authorAyvaz, Hüseyin
dc.contributor.authorCabaroğlu, Turgut
dc.contributor.authorAkyıldız, Asiye
dc.contributor.authorUysal Pala, Ciğdem
dc.contributor.authorTemizkan, Rıza
dc.contributor.authorAğcam, Erdal
dc.contributor.authorAyvaz, Zayde
dc.date.accessioned2024-01-24T06:38:34Z
dc.date.available2024-01-24T06:38:34Z
dc.date.issued2023en_US
dc.departmentFakülteler, Deniz Bilimleri ve Teknolojisi Fakültesi, Deniz Teknoloji Mühendisliği Bölümü
dc.departmentFakülteler, Mühendislik Fakültesi, Gıda Mühendisliği Bölümü
dc.description.abstractIn this work, various concepts and features of anthocyanins have been comprehensively reviewed, taking the benefits of the scientific publications released mainly within the last five years. Within the paper, common topics such as anthocyanin chemistry and occurrence, including the biosynthesis of anthocyanins emphasizing the anthocyanin formation pathway, anthocyanin chemistry, and factors influencing the anthocyanins’ stability, are covered in detail. By evaluating the recent in vitro and human experimental studies on the absorption and bioavailability of anthocyanins present in typical food and beverages, this review elucidates the significant variations in biokinetic parameters based on the model, anthocyanin source, and dose, allowing us to make basic assumptions about their bioavailability. Additionally, special attention is paid to other topics, such as the therapeutic effects of anthocyanins. Reviewing the recent in vitro, in vivo, and epidemiological studies on the therapeutic potential of anthocyanins against various diseases permits a demonstration of the promising efficacy of different anthocyanin sources at various levels, including the neuroprotective, cardioprotective, antidiabetic, antiobesity, and anticancer effects. Additionally, the studies on using plant-based anthocyanins as coloring food mediums are extensively investigated in this paper, revealing the successful use of anthocyanins in coloring various products, such as dietary and bakery products, mixes, juices, candies, beverages, ice cream, and jams. Lastly, the successful application of anthocyanins as prebiotic ingredients, the innovation potential of anthocyanins in industry, and sustainable sources of anthocyanins, including a quantitative research literature and database analysis, is performed.en_US
dc.identifier.citationAyvaz, H., Cabaroğlu, T., Akyıldız, A., Pala, C. U., Temizkan, R., Ağçam, E., … Diaconeasa, Z. (2023). Anthocyanins: Metabolic Digestion, Bioavailability, Therapeutic Effects, Current Pharmaceutical/Industrial Use, and Innovation Potential. Antioxidants, 12(1). https://doi.org/10.3390/antiox12010048en_US
dc.identifier.doi10.3390/antiox12010048
dc.identifier.issn2076-3921
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85146738125
dc.identifier.urihttps://doi.org/10.3390/antiox12010048
dc.identifier.urihttps://hdl.handle.net/20.500.12428/5363
dc.identifier.volume12en_US
dc.identifier.wosWOS:000914484700001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorAyvaz, Hüseyin
dc.institutionauthorUysal Pala, Ciğdem
dc.institutionauthorTemizkan, Rıza
dc.institutionauthorAyvaz, Zayde
dc.language.isoen
dc.publisherMDPIen_US
dc.relation.ispartofAntioxidantsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subjectAnthocyaninsen_US
dc.subjectBioavailabilityen_US
dc.subjectBiosynthesisen_US
dc.subjectIndustrial applicationsen_US
dc.subjectPharmaceutical usesen_US
dc.subjectTherapeutic effecten_US
dc.titleAnthocyanins: Metabolic Digestion, Bioavailability, Therapeutic Effects, Current Pharmaceutical/Industrial Use, and Innovation Potential
dc.typeArticle

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