Evaluation of the Diagnostic Performance of a SARS-CoV-2 and Influenza A/B Combo Rapid Antigen Test in Respiratory Samples

Basit Öğe Kaydı
dc.authorid0000-0003-0574-3578en_US
dc.authorscopusid6602233637en_US
dc.authorwosidD-4674-2019en_US
dc.contributor.authorDinç, Harika Öykü
dc.contributor.authorKarabulut, Nuran
dc.contributor.authorAlaçam, Sema
dc.contributor.authorKırkoyun Uysal, Hayriye
dc.contributor.authorDaşdemir, Ferhat Osman
dc.contributor.authorÖnel, Mustafa
dc.contributor.authorÇakan, Hüseyin
dc.date.accessioned2024-01-22T07:41:43Z
dc.date.available2024-01-22T07:41:43Z
dc.date.issued2023en_US
dc.departmentFakülteler, Fen Fakültesi, Biyoloji Bölümü
dc.description.abstractThis study aimed to evaluate the performance characteristics of a rapid antigen test developed to detect SARS-CoV-2 (COVID-19), influenza A virus (IAV), and influenza B virus (IBV) (flu) compared with those of the real-time reverse transcription-polymerase chain reaction (rRT-PCR) method. One hundred SARS-CoV-2, one hundred IAV, and twenty-four IBV patients whose diagnoses were confirmed by clinical and laboratory methods were included in the patient group. Seventy-six patients, who were negative for all respiratory tract viruses, were included as the control group. The Panbio™ COVID-19/Flu A&B Rapid Panel test kit was used in the assays. The sensitivity values of the kit were 97.5%, 97.9%, and 33.33% for SARS-CoV-2, IAV, and IBV, respectively, in samples with a viral load below 20 Ct values. The sensitivity values of the kit were 16.7%, 36.5%, and 11.11% for SARS-CoV-2, IAV, and IBV, respectively, in samples with a viral load above 20 Ct. The kit’s specificity was 100%. In conclusion, this kit demonstrated high sensitivity to SARS-CoV-2 and IAV for viral loads below 20 Ct values, but the sensitivity values were not compatible with PCR positivity for lower viral loads over 20 Ct values. Rapid antigen tests may be preferred as a routine screening tool in communal environments, especially in symptomatic individuals, when diagnosing SARS-CoV-2, IAV, and IBV with high caution.en_US
dc.identifier.citationDinç, H. Ö., Karabulut, N., Alaçam, S., Uysal, H. K., Daşdemir, F. O., Önel, M., … Kocazeybek, B. (2023). Evaluation of the Diagnostic Performance of a SARS-CoV-2 and Influenza A/B Combo Rapid Antigen Test in Respiratory Samples. Diagnostics, 13(5). https://doi.org/10.3390/diagnostics13050972en_US
dc.identifier.doi10.3390/diagnostics13050972
dc.identifier.issn2075-4418
dc.identifier.issue5en_US
dc.identifier.pmid36900116
dc.identifier.scopus2-s2.0-85149754344
dc.identifier.urihttps://doi.org/10.3390/diagnostics13050972
dc.identifier.urihttps://hdl.handle.net/20.500.12428/5282
dc.identifier.volume13en_US
dc.identifier.wosWOS:000947576000001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÇakan, Hüseyin
dc.language.isoen
dc.publisherMDPIen_US
dc.relation.ispartofDiagnosticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subjectAntigen testsen_US
dc.subjectInfluenza Aen_US
dc.subjectInfluenza Ben_US
dc.subjectRapid testen_US
dc.subjectSARS-CoV-2en_US
dc.titleEvaluation of the Diagnostic Performance of a SARS-CoV-2 and Influenza A/B Combo Rapid Antigen Test in Respiratory Samples
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Huseyin_Cakan_Makale.pdf
Boyut:
1.13 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Araştırma Makalesi
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Biyoloji Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu