Retina and Optic Disc Characteristics in Amblyopic and Non-amblyopic Eyes of Patients with Myopic or Hyperopic Anisometropia

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dc.contributor.authorComez, Arzu Taskiran
dc.contributor.authorUlu, Elif Sanal
dc.contributor.authorEkim, Yeliz
dc.date.accessioned2025-01-27T20:47:24Z
dc.date.available2025-01-27T20:47:24Z
dc.date.issued2017
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjectives: To compare retinal and optic disc characteristics between amblyopic and non-amblyopic eyes in patients with myopic and hyperopic anisometropia measured with optical coherence tomography (OCT). Materials and Methods: Patients with myopic (25 patients: 17 female, 8 male; median age 27 years, range 16-40 years) and hyperopic (31 patients: 19 female, 12 male; median age 20 years, range 13-41 years) anisometropic amblyopia were included. Eye examination included determination of best-corrected visual acuity (BCVA) with a Snellen chart, measurement of manifest and cycloplegic refraction after pupillary dilation, alternate cover testing, globe movement evaluation, A-scan biometry for axial length, biomicroscopy, fundus examination, and OCT scanning. Main outcome measures were spherical equivalence, BCVA, axial length, retinal nerve fiber layer (RNFL) thickness, macular thickness, macular volume, and optic disc area. Results: In both myopic and hyperopic patients, the absolute value of the mean spherical equivalence was significantly greater in the amblyopic than non-amblyopic eyes, and the mean BCVA was significantly less in the amblyopic than the non-amblyopic eyes. In both myopic and hyperopic patients, there were no significant differences in mean RNFL thickness, macular thickness, macular volume, axial length, or optic disc area between amblyopic and non-amblyopic eyes. Conclusion: The amblyopic process may have no significant effect on the RNFL, macula, or optic disc. Further studies with more patients, including postmortem studies, may clarify the retinal, histopathologic, and anatomic differences between amblyopic and nonamblyopic eyes.
dc.identifier.doi10.4274/tjo.54289
dc.identifier.endpage33
dc.identifier.issn1300-0659
dc.identifier.issn2147-2661
dc.identifier.issue1
dc.identifier.pmid28182148
dc.identifier.scopus2-s2.0-85010992352
dc.identifier.scopusqualityN/A
dc.identifier.startpage28
dc.identifier.trdizinid287551
dc.identifier.urihttps://doi.org/10.4274/tjo.54289
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/287551
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24882
dc.identifier.volume47
dc.identifier.wosWOS:000397190800007
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Ophthalmological Soc
dc.relation.ispartofTurk Oftalmoloji Dergisi-Turkish Journal of Ophthalmology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectAnisometropia
dc.subjectamblyopia
dc.subjectmacula
dc.subjectretinal nerve fiber layer
dc.subjectoptical coherence tomography
dc.titleRetina and Optic Disc Characteristics in Amblyopic and Non-amblyopic Eyes of Patients with Myopic or Hyperopic Anisometropia
dc.typeArticle

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