Identification and comparison of N-glycome profiles from common dietary protein sources

Basit Öğe Kaydı
dc.contributor.authorBolino, Matthew
dc.contributor.authorAvci, Izzet
dc.contributor.authorKayili, Haci Mehmet
dc.contributor.authorDuman, Hatice
dc.contributor.authorSalih, Bekir
dc.contributor.authorKarav, Sercan
dc.contributor.authorFrese, Steven A.
dc.date.accessioned2025-01-27T20:34:35Z
dc.date.available2025-01-27T20:34:35Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThe N-glycomes of bovine whey, egg white, pea, and soy protein isolates are described here. N-glycans from four protein isolates were analyzed by HILIC high performance liquid chromatography and quadrupole time-of-flight tandem mass spectrometry (HILIC-FLD-QTOF-MS/MS). In total, 33 N-glycans from bovine whey and egg white and 10 N-glycans from soy and pea glycoproteins were identified. The type of N-glycans per glycoprotein source were attributable to differences in biosynthetic glycosylation pathways. Animal glycoprotein sources favored a combination of complex and hybrid glycan configurations, while the plant proteins were dominated by oligomannosidic N-glycans. Bovine whey glycoprotein isolate contained the most diverse N-glycans by monosaccharide composition as well as structure, while plant sources such as pea and soy glycoprotein isolates contained an overlap of oligomannosidic N-glycans. The results suggest N-glycan structure and composition is dependent on the host organism which are driven by the differences in N-glycan biosynthetic pathways.
dc.identifier.doi10.1016/j.fochx.2024.102025
dc.identifier.issn2590-1575
dc.identifier.pmid39758068
dc.identifier.scopus2-s2.0-85211978500
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1016/j.fochx.2024.102025
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23364
dc.identifier.volume25
dc.identifier.wosWOS:001386228000001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofFood Chemistry-X
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectN-glycan
dc.subjectProtein
dc.subjectMass spectrometry
dc.subjectMicrobiome
dc.subjectN-glycome
dc.subjectGlycan
dc.titleIdentification and comparison of N-glycome profiles from common dietary protein sources
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu