Synthesis, Molecular Structure, Biological Activity, and Sensor Properties of (E)-2-[(3,5-Bis(trifluoromethyl)phenylimino)methy1]-4,6-dichlorophenol
Yükleniyor...
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Pleiades Publishing, Ltd.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In the present study, a Schiff base (E)-2-[(3,5-bis(trifl uoromethyl)phenylimino)methyl]-4,6-dichlorophenol has been synthesized. Its spectroscopic and X-ray single-crystal data have been compared with the results of theoretical calculations based on the DFT method, as well as molecular electrostatic potential (MEP), HOMO and LUMO, and nonlinear optical (NLO) effects. Antimicrobial activity of the compound has been tested against some bacteria and fungi. According to UV-Vis and agarose gel electrophoresis methods, the compound interacts with DNA electrostatically and breaks it oxidatively. Antioxidant activity of the compound measured by the DPPH method, is lower than that of BHT.
Açıklama
Anahtar Kelimeler
Single crystal, DFT, DNA interactions, Antioxidant, Sensor applications
Kaynak
Russian Journal of General Chemistry
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
91
Sayı
2
Künye
Zeyrek, C. T., Boyacıoğlu, B., Demir, N., Tümer, Y., Kiraz, A., Ünver, H., & Yıldız, M. (2021). Synthesis, molecular structure, biological activity, and sensor properties of (E)-2-[(3,5-bis(trifluoromethyl) phenylamino)methyl]-4,6-dichlorophenol. Russian Journal of General Chemistry, 91(2), 279-284. doi:10.1134/S107036322102016X
