Mitral annular plane systolic excursion in the assessment of left ventricular diastolic dysfunction in obese adults

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dc.contributor.authorTasolar, Hakan
dc.contributor.authorMete, Turkan
dc.contributor.authorCetin, Mustafa
dc.contributor.authorAltun, Burak
dc.contributor.authorBalli, Mehmet
dc.contributor.authorBayramoglu, Adil
dc.contributor.authorOtlu, Yilmaz Omur
dc.date.accessioned2025-01-27T20:58:21Z
dc.date.available2025-01-27T20:58:21Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: Mitral annular plane systolic excursion (MAPSE) is a simple way to assess left ventricle (LV) function. MAPSE is also correlated to parameters, illustrating the close relation between systolic and diastolic function of LV. In this study, we evaluated whether MAPSE could help us in the determination the LV diastolic dysfunction (DD) in obese adults. Methods: Our study was a prospective cross-sectional study. Obese patients who were referred from the endocrinology clinic were enrolled into this study. The participants included 40 obese patients with early-stage DD (grade I and II) and 40 obese patients with normal diastolic function, with an equal number of males and females. The patients with DD were further divided into Obese DD+I, who had grade I DD, and Obese DD+II, who had grade II DD. Student t-test, Mann-Whitney U test, one-way analysis of variance, ROC curve analysis, and pairwise comparisons of the ROC curves were used for statistical analysis. Results: MAPSE was different in all groups, with the lowest value in the Obese DD+II group (p<0.001). E/Em ratio was also different among all groups and was highest in the Obese DD+II group (p<0.001). Furthermore, MAPSE was negatively correlated with E/Em ratio (r=-0.368, p=0.020). The optimal threshold point of MAPSE in the diagnosis of left ventricle diastolic dysfunction (LVDD) was <= 1.45 cm, with 92.5% sensitivity (95% CI 79.6-98.4) and 77.5% specificity (95% CI 61.5-89.2) in the ROC curve analysis. There was no difference in the pairwise comparisons of the ROC curves of MAPSE and E/Em ratio in the diagnosis of DD [area under the ROC curve 0.902 (0.033) vs. 0.927 (0.027); p=0.54]. Conclusion: Consequently, we found significantly a close relationship between MAPSE with conventional echocardiographic parameters, especially with E/Em, in the detection of left ventricle diastolic dysfunction (LVDD) in obese adults with normal LV ejection fraction. We think that MAPSE is a simple, easily acquired and less time consuming measurement and may help us in the stratification of LVDD in obese adults.
dc.identifier.doi10.5152/akd.2014.5561
dc.identifier.endpage564
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue7
dc.identifier.pmid25537997
dc.identifier.scopus2-s2.0-84973413765
dc.identifier.scopusqualityN/A
dc.identifier.startpage558
dc.identifier.trdizinid173745
dc.identifier.urihttps://doi.org/10.5152/akd.2014.5561
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/173745
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26681
dc.identifier.volume15
dc.identifier.wosWOS:000357329900009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Soc Cardiology
dc.relation.ispartofAnatolian Journal of Cardiology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectmitral annular plane systolic excursion
dc.subjectobesity
dc.subjectleft ventricle diastolic dysfunction
dc.titleMitral annular plane systolic excursion in the assessment of left ventricular diastolic dysfunction in obese adults
dc.typeArticle

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