A Review on Phyto-Therapeutic Approaches in Alzheimer's Disease

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dc.authorid0000-0001-8666-7954en_US
dc.authorid0000-0002-5260-7678en_US
dc.authorid0000-0002-5802-1635en_US
dc.authorid0000-0003-0120-530Xen_US
dc.authorscopusid24472372400en_US
dc.authorscopusid57928942000en_US
dc.authorscopusid57929125800en_US
dc.authorscopusid6602001525en_US
dc.authorwosidAAB-6714-2020en_US
dc.authorwosid-en_US
dc.authorwosid-en_US
dc.authorwosidDVD-0927-2022en_US
dc.contributor.authorŞahiner, Mehtap
dc.contributor.authorYılmaz, Aynur Sanem
dc.contributor.authorGüngör, Buket
dc.contributor.authorŞahiner, Nurettin
dc.date.accessioned2024-01-24T07:44:02Z
dc.date.available2024-01-24T07:44:02Z
dc.date.issued2023en_US
dc.departmentFakülteler, Fen Fakültesi, Kimya Bölümü
dc.departmentFakülteler, Mühendislik Fakültesi, Biyomühendislik Bölümü
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.departmentRektörlük, Rektörlüğe Bağlı Bölümler, Nanobilim ve Teknoloji Araştırma ve Uygulama Merkezi
dc.descriptionScopus Pubmed FEF Kimya Müh. Fak. Biyomühendislik Rektörlük Nanoteknoloji Merkezien_US
dc.description.abstractNeurodegenerative diseases occur due to progressive and sometimes irreversible loss of function and death of nerve cells. A great deal of effort is being made to understand the pathogenesis of neurodegenerative diseases. In particular, the prevalence of Alzheimer’s disease (AD) is quite high, and only symptomatic therapy is available due to the absence of radical treatment. The aim of this review is to try to elucidate the general pathogenesis of AD, to provide information about the limit points of symptomatic treatment approaches, and to emphasize the potential neurologic effects of phytocompounds as new tools as therapeutic agents for disease prevention, retardation, and therapy. This survey also covers the notable properties of herbal compounds such as their effects on the inhibition of an enzyme called acetylcholinesterase, which has significant value in the treatment of AD. It has been proven that phytopharmaceuticals have long-term effects that could protect nervous system health, eliminate inflammatory responses, improve cognitive damage, provide anti-aging effects in the natural aging process, and alleviate dementia sequelae. Herbal-based therapeutic agents can afford many advantages and can be used as potentially as new-generation therapeutics or complementary agents with high compliance, fewer adverse effects, and lower cost in comparison to the traditional pharmaceutical agents in the fight against AD.en_US
dc.identifier.citationŞahiner, M., Yılmaz, A. S., Güngor, B., & Şahiner, N. (2023). A Review on Phyto-Therapeutic Approaches in Alzheimer’s Disease. Journal of Functional Biomaterials, 14(1). https://doi.org/10.3390/jfb14010050en_US
dc.identifier.doi10.3390/jfb14010050
dc.identifier.issn2079-4983
dc.identifier.issue1en_US
dc.identifier.pmid36662097
dc.identifier.scopus2-s2.0-85146681810
dc.identifier.urihttps://doi.org/10.3390/jfb14010050
dc.identifier.urihttps://hdl.handle.net/20.500.12428/5370
dc.identifier.volume14en_US
dc.identifier.wosWOS:000915095500001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorŞahiner, Mehtap
dc.institutionauthorYılmaz, Aynur Sanem
dc.institutionauthorGüngör, Buket
dc.institutionauthorŞahiner, Nurettin
dc.language.isoen
dc.publisherMDPIen_US
dc.relation.ispartofJournal of Functional Biomaterialsen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subjectEnzyme inhibitorsen_US
dc.subjectMetal chelatingen_US
dc.subjectNeurodegenerative diseasesen_US
dc.subjectPhytocompoundsen_US
dc.subjectPolyphenolicsen_US
dc.titleA Review on Phyto-Therapeutic Approaches in Alzheimer's Disease
dc.typeReview Article

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