Comparison of different risk stratification systems for prediction of acute pancreatitis severity in patients referred to the emergency department of a tertiary care hospital

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dc.authoridBARDAKCI, OKAN/0000-0001-6829-7435
dc.contributor.authorBardakci, Okan
dc.contributor.authorAkdur, Gokhan
dc.contributor.authorDas, Murat
dc.contributor.authorSiddikoglu, Duygu
dc.contributor.authorAkdur, Okhan
dc.contributor.authorBeyazit, Yavuz
dc.date.accessioned2025-01-27T20:56:28Z
dc.date.available2025-01-27T20:56:28Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBACKGROUND: Prognostic prediction and estimation of severity at early stages of acute pancreatitis (AP) are crucial to reduce the complication rates and mortality. The objective of the present study is to evaluate the predicting ability of different clinical and radiological scores in AP. METHODS: We retrospectively collected demographic and clinical data from 159 patients diagnosed with AP admitted to Canakkale Onsekiz Mart University Hospital between January 2017 and December 2019. Bedside index for severity AP (BISAP), and acute phys-iology and chronic health evaluation II (APACHE II) score at admission, Ranson and modified Glasgow Prognostic Score (mGPS) score at 48 h after admission were calculated. Modified computed tomography severity index (CTSI) was also calculated for each patient. Area under the curve (AUC) was calculated for each scoring system for predicting severe AP, pancreatic necrosis, length of hospital stay, and mortality by determining optimal cutoff points from the (ROC) curves. RESULTS: mGPS and APACHE II had the highest AUC (0.929 and 0.823, respectively) to predict severe AP on admission with the best specificity and sensitivity. In predicting mortality BISAP (with a sensitivity, specificity, negative predictive value (NPV), and positive predictive value (PPV) of 75.0%, 70.9%, 98.2%, and 12.0%, respectively, [AUC: 0.793]) and APACHE II (with a sensitivity, specificity, NPV and PPV of 87.5%, 86.1%, 99.2%, and 25.0%, respectively, [AUC: 0.840]). CONCLUSION: mGPS can be a valuable tool in predicting the patients more likely to develop severe AP and maybe somewhat better than BISAP score, APACHE II Ranson score, and mCTSI.
dc.identifier.doi10.14744/tjtes.2021.51892
dc.identifier.endpage973
dc.identifier.issn1306-696X
dc.identifier.issn1307-7945
dc.identifier.issue7
dc.identifier.pmid35775674
dc.identifier.scopus2-s2.0-85133275190
dc.identifier.scopusqualityQ3
dc.identifier.startpage967
dc.identifier.trdizinid1136082
dc.identifier.urihttps://doi.org/10.14744/tjtes.2021.51892
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1136082
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26411
dc.identifier.volume28
dc.identifier.wosWOS:000826601600012
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Assoc Trauma Emergency Surgery
dc.relation.ispartofUlusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectAcute pancreatitis
dc.subjectacute physiology and chronic health evaluation II
dc.subjectbedside index for severity acute pancreatitis
dc.subjectModified Glasgow prognostic score
dc.subjectRanson
dc.titleComparison of different risk stratification systems for prediction of acute pancreatitis severity in patients referred to the emergency department of a tertiary care hospital
dc.title.alternativeÜçüncü basamak bir hastanenin acil servisine sevk edilen akut pankreatitli hastaların şiddetinin öngörülmesinde farklı risk sınıflandırma sistemlerinin karşılaştırılması
dc.typeArticle

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