Relationship between presence of fragmented QRS on 12-lead electrocardiogram on admission and long-term mortality in patients with non-ST elevated myocardial infarction

Basit Öğe Kaydı
dc.contributor.authorBekler, Adem
dc.contributor.authorGazi, Emine
dc.contributor.authorErbag, Gokhan
dc.contributor.authorPeker, Tezcan
dc.contributor.authorBarutcu, Ahmet
dc.contributor.authorAltun, Burak
dc.contributor.authorTemiz, Ahmet
dc.date.accessioned2025-01-27T21:21:21Z
dc.date.available2025-01-27T21:21:21Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjectives: Fragmented QRS (fQRS) as a predictor of cardiac events in coronary artery disease has previously been reported. In this study, we hypothesized that presence of fQRS on a 12-lead electrocardiogram (ECG) on admission would be predictive of adverse outcomes in non-ST elevated myocardial infarction (NSTEMI). Study design: A total of 149 NSTEMI patients (112 male, 37 female) were retrospectively analyzed. The fQRS pattern was defined as the presence of an additional R', notching in the nadir of the S wave, fragmentation of the RS or QS complexes in 2 contiguous leads corresponding to a major coronary artery territory. The relationship between presence of fQRS on admission on a 12-lead ECG, and primary end points [cardiovascular death (CVD)] and secondary end points (re-infarction, repeat target vessel revascularization [percutaneous/surgical]) were assessed. The median follow-up time was 18 (13-24) months. Results: Other than age, there were no significant differences in baseline characteristics and laboratory findings for patients in the fQRS and non-fQRS groups. The patients in the fQRS group were older [64 years vs 59 years, p=0.048]. CVD and re-infarction were significantly higher in the fQRS group in the median 18- month follow-up (26.1% vs 8.7%, p=0.005; 23.9% vs 10.7%, p=0.035, respectively). By a multivariate regression analysis in all 149 patients, age = 65 years and the presence of fQRS in a 12-lead ECG on admission were found to be powerful independent predictors of cardiovascular mortality (HR: 4.91, 95% CI: 1.60-15.03, p=0.005; HR: 2.77, 95% CI: 1.02-7.50, p=0.044, respectively). Conclusion: Presence of fQRS on a 12-lead ECG on admission is associated with increased long-term mortality in patients with NSTEMI.
dc.identifier.doi10.5543/tkda.2014.79438
dc.identifier.endpage732
dc.identifier.issn1016-5169
dc.identifier.issue8
dc.identifier.pmid25620333
dc.identifier.scopus2-s2.0-84931834641
dc.identifier.scopusqualityQ3
dc.identifier.startpage726
dc.identifier.trdizinid192867
dc.identifier.urihttps://doi.org/10.5543/tkda.2014.79438
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/192867
dc.identifier.urihttps://hdl.handle.net/20.500.12428/28908
dc.identifier.volume42
dc.identifier.wosWOS:000421952600006
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Soc Cardiology
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivi-Archives of The Turkish Society of Cardiology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectAcute coronary syndrome
dc.subjectfragmented QRS
dc.subjectmyocardial infarction
dc.subjectmortality
dc.titleRelationship between presence of fragmented QRS on 12-lead electrocardiogram on admission and long-term mortality in patients with non-ST elevated myocardial infarction
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu