Regional variations in psoriatic arthritis: Insights from a nationwide multicenter analysis in Türkiye

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dc.authoridYurdakul, Ozan Volkan/0000-0003-4567-8133
dc.authoridcuzdan balta, nihan/0000-0001-7238-657X
dc.authoridNAS, Kemal/0000-0002-5845-0851
dc.authoridAcer Kasman, Sevtap/0000-0002-4805-0555
dc.contributor.authorKilic, Erkan
dc.contributor.authorKilic, Gamze
dc.contributor.authorTekeoglu, Ibrahim
dc.contributor.authorSargin, Betul
dc.contributor.authorKasman, Sevtap Acer
dc.contributor.authorAlkan, Hakan
dc.contributor.authorSahin, Nilay
dc.date.accessioned2025-01-27T20:25:04Z
dc.date.available2025-01-27T20:25:04Z
dc.date.issued2024
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjectives: The study aimed to investigate and compare clinical features, disease activity, and the overall disease burden among psoriatic arthritis (PsA) patients across seven distinct geographic regions in T & uuml;rkiye. Patients and methods: A multicenter cross-sectional study involving 1,134 PsA patients from 25 referral centers across seven regions was conducted. Demographic and clinical characteristics, comorbidities, joint involvement, extra-articular manifestations, and disease activity measures were evaluated across regions. Results: A total of 1134 PsA patients from seven different geographic regions in T & uuml;rkiye participated in this study. The highest number of participants was from the Marmara region (n=409), with subsequent representation from Central Anatolia (n=370), Aegean (n=139), Mediterranean (n=60), Black Sea (n=60), Eastern Anatolia (n=60), and Southeastern Anatolia (n=36) regions. There were significant variations in demographic profile, including age, body mass index, age of disease onset, educational status, comorbidities, and family history of both psoriasis and PsA. Clinical features, such as enthesitis, dactylitis, uveitis, and joint involvement, demonstrated significant variation across regions. Additionally, disease activity measures, including pain, patient and physician global assessments, acute phase reactants, disease activity indices, quality of life, and functional status, displayed considerable regional differences. Conclusion: This nationwide study revealed substantial regional diversity in demographic data, clinical characteristics, disease activity, and quality of life among PsA patients in T & uuml;rkiye. These findings stress the need to customize treatment approaches to address regional needs and to conduct further research to uncover reasons for disparities. It is crucial to enhance region-specific approaches to improve patient care and outcomes for PsA.
dc.identifier.doi10.46497/ArchRheumatol.2024.10591
dc.identifier.endpage349
dc.identifier.issn2618-6500
dc.identifier.issue3
dc.identifier.pmid39507837
dc.identifier.scopus2-s2.0-85203023813
dc.identifier.scopusqualityQ3
dc.identifier.startpage339
dc.identifier.trdizinid1273088
dc.identifier.urihttps://doi.org/10.46497/ArchRheumatol.2024.10591
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1273088
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22425
dc.identifier.volume39
dc.identifier.wosWOS:001306482800001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish League Against Rheumatism
dc.relation.ispartofArchives of Rheumatology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectArthritis
dc.subjectdifferences
dc.subjectgeographic locations
dc.subjectpsoriatic
dc.subjectregional
dc.subjectspondyloarthritis
dc.titleRegional variations in psoriatic arthritis: Insights from a nationwide multicenter analysis in Türkiye
dc.typeArticle

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