Friend or foe? A critical evaluation of compositional quality and antibiotic resistance profiles of probiotic dietary supplements in Türkiye

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dc.authoridUymaz Tezel, Başar / 0000-0002-4156-8861
dc.contributor.authorSeyirt, Seda
dc.contributor.authorUymaz Tezel, Başar
dc.contributor.authorSanlibaba, Pinar
dc.date.accessioned2025-05-29T02:57:37Z
dc.date.available2025-05-29T02:57:37Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThis study analyzed 10 commercial probiotic dietary supplements for the enumeration and identification of lactobacilli and bifidobacteria, as well as their antibiotic resistance profiles. The isolated strains were identified using molecular methods, and their resistance to 18 antibiotics was assessed using the disc diffusion method. Four of the tested products had a lower number of viable bacteria than stated on the label. A total of 13 presumptive lactobacilli and bifidobacteria strains were identified using molecular methods. The results showed discrepancies between the bacterial species listed on the labels of some products and the actual strains present. All of the Lactobacillus strains were resistant to methicillin, cefoxitin, and vancomycin. Furthermore, low levels of resistance to cefazolin, enrofloxacin, ciprofloxacin, norfloxacin, kanamycin, and trimethoprim was observed in Lactobacillus spp. All Bifidobacterium strains were resistant to methicillin and vancomycin. In addition, Bifidobacterium spp. strains that were resistant to cefazolin, cefoxiti, kanamycin, norfloxacin, ampicillin, clindamycin, enrofloxacin, trimethoprim, and ciprofloxacin were determined. Multidrug resistance was found in all Lactobacillus and Bifdobacterium strains. Finally, MDR rates were found to be 100% in both Bifidobacterium and Lactobacillus species. The MAR index indicated a high-risk source of contamination for most strains, with 11 out of 13 strains exceeding the threshold of 0.2. These findings emphasize the critical role of precise labeling in fostering consumer trust and enabling informed decision-making. Antibiotic resistance should be regarded a significant part of the safety assessment of probiotics. Novel approaches will be essential for addressing MDR bacteria. MAR index findings highlight the need for stricter quality control in probiotic product labeling and a closer examination of antibiotic resistance in probiotic strains, given their potential implications for health and safety.
dc.description.sponsorshipanakkale Onsekiz Mart University Scientific Research Projects Coordination Unit [FBA-2021-3629]
dc.description.sponsorshipThis work was supported by the Canakkale Onsekiz Mart University Scientific Research Projects Coordination Unit (Project number FBA-2021-3629) .
dc.identifier.doi10.15586/ijfs.v37i2.2955
dc.identifier.endpage204
dc.identifier.issn1120-1770
dc.identifier.issn2239-5687
dc.identifier.issue2
dc.identifier.scopus2-s2.0-105002032133
dc.identifier.scopusqualityQ2
dc.identifier.startpage188
dc.identifier.urihttps://doi.org/10.15586/ijfs.v37i2.2955
dc.identifier.urihttps://hdl.handle.net/20.500.12428/30099
dc.identifier.volume37
dc.identifier.wosWOS:001463713300012
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherCodon Publications
dc.relation.ispartofItalian Journal of Food Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250529
dc.subjectLabel correctness
dc.subjectantibiotic resistance
dc.subjectprobiotics dietary supplements
dc.subjectBifidobacterium spp.
dc.subjectLactobacillus spp
dc.titleFriend or foe? A critical evaluation of compositional quality and antibiotic resistance profiles of probiotic dietary supplements in Türkiye
dc.typeArticle

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