Evaluation of Depression with Mixed Features and Bipolarity Screening in Patients with Epilepsy

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dc.authorid0000-0003-3331-8165en_US
dc.authorscopusid57044442800en_US
dc.authorwosidAAZ-2347-2021en_US
dc.contributor.authorAkıncı, Erhan
dc.contributor.authorBaşaran, Şehnaz
dc.contributor.authorTaş, Halil İbrahim
dc.date.accessioned2023-05-15T10:03:45Z
dc.date.available2023-05-15T10:03:45Z
dc.date.issued2021en_US
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractObjective: To investigate depression with mixed features (MXD) and risk of bipolarity and to explore the association between clinical variables in patients with epilepsy. Materials and Methods: A total of 62 patients who were followed up with epilepsy diagnosis at least 2 years were enrolled. Demographic and clinical data were collected using face to face interview. All subjects also performed modified hypomania checklist (mHCL), Beck depression inventory (BDI), and the mood disorder questionnaire (MDQ). Results: According to the BDI, 25 (40.3%) of the cases required additional psychiatric examination for depression. MDQ scores indicated that 7 (9.7%) of the cases required additional psychiatric evaluation for bipolar disorder. Due to the mHCL assessment, 20 (32.2%) cases had at least 3 manic symptoms, and 9 (14.5%) cases had at least 13 manic symptoms of mixed depression. A significant positive correlation was found between the scores of BDI and mHCL (r = 0.338, P = .007) and the scores of mHCL and MDQ (r = 0.694, P < .001). In addition, bipolarity risk was significantly higher in patients with generalized epilepsy, than partial epilepsy (P = .040). Conclusion: Our results suggest that MXD is more common and the risk of bipolarity is higher in patients with epilepsy. Therefore, clinical assessment of MXD is substantial for determining bipolarity in epileptic individuals.en_US
dc.identifier.citationAkıncı, E., Başaran, Ş., Taş, H. İ. (2021). Evaluation of Depression with Mixed Features and Bipolarity Screening in Patients with Epilepsy. Psychiatry and Clinical Psychopharmacology, 31(1), 77-82. doi:10.5152/pcp.2021.20163en_US
dc.identifier.doi10.5152/pcp.2021.20163
dc.identifier.endpage82en_US
dc.identifier.issn2475-0573
dc.identifier.issn2475-0581
dc.identifier.issue1en_US
dc.identifier.pmid39619348
dc.identifier.scopus2-s2.0-85129907238
dc.identifier.startpage77en_US
dc.identifier.trdizinid1169240
dc.identifier.urihttps://hdl.handle.net/20.500.12428/4133
dc.identifier.urihttps://doi.org/10.5152/pcp.2021.20163en_US
dc.identifier.volume31en_US
dc.identifier.wosWOS:000638999100010
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.institutionauthorAkıncı, Erhan
dc.language.isoen
dc.publisherAVESen_US
dc.relation.ispartofPsychiatry and Clinical Psychopharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/us/*
dc.subjectBipolarityen_US
dc.subjectDepressionen_US
dc.subjectEpilepsyen_US
dc.subjectMixed featuresen_US
dc.titleEvaluation of Depression with Mixed Features and Bipolarity Screening in Patients with Epilepsy
dc.typeArticle

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