Early detection of myocardial deformation by 2D speckle tracking echocardiography in normotensive obese children and adolescents

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dc.authoridYildirim, Sule/0000-0002-1815-808X
dc.authoridAylanc, Hakan/0000-0002-8907-3809
dc.contributor.authorBinnetoglu, Fatih Koksal
dc.contributor.authorYildirim, Sule
dc.contributor.authorTopaloglu, Naci
dc.contributor.authorTekin, Mustafa
dc.contributor.authorKaymaz, Nazan
dc.contributor.authorAylanc, Hakan
dc.contributor.authorKarakurt, Hasan
dc.date.accessioned2025-01-27T20:41:32Z
dc.date.available2025-01-27T20:41:32Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: To evaluate the left venticular myocardial deformation parameters in normotensive obese children and adolescents by using 2-D speckle tracking echocardiography. Methods: This observational cross-sectional study included 69 children and adolescents (aged between 10-18), 38 were normotensive obese and 31 were normal weighted. All children underwent detailed two-dimentional, Doppler and two-dimentional speckle tracking echocardiography. Student t-test, Mann-Whitney U test, chi-square test and Pearson's correlation were used in statistical analysis. Multiple linear regression analysis was used the determine independent variables on global longitudinal strain (GLS). Results: While in normal limits, diastolic blood pressure was significantly higher in obese group. Left ventricular end-diastolic diameter (LVDd) and end-systolic diameter (LVDs), interventricular septal thickness (IVSd), left ventricular posterior wall thickness (LPWD) and left ventricular mass index (LVM)/height2.7 were significantly higher in obese group compared to healthy peers (p=0.004, p=0.011, p<0.001, p=0.001, p<0.001) respectively. Obese subjects had reduced global longitudinal strain (GLS) values (p=0.001). Multiple linear regression analysis using the stepwise method were performed to assess the independent variables (age, body mass index, insulin resistance, systolic blood pressure, diastolic blood pressure, left ventricular diameters and LVM index (g/m2.7) affecting the dependent variable GLS. GLS was found significantly correlated with body mass index (BMI) (beta:0.440, p:0.001; 95% CI:0.104-0.311). Conclusion: Left ventricular strain parameters obtained by two dimentional speckle tracking echocardiography were diminished in obese children compared to normal subjects indicating that obesity in childhood is linked to decreased myocardial deformation even in the absence of comorbidities in early stages.
dc.identifier.doi10.5152/akd.2014.5189
dc.identifier.endpage157
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue2
dc.identifier.pmid25252300
dc.identifier.scopus2-s2.0-84979097472
dc.identifier.scopusqualityN/A
dc.identifier.startpage151
dc.identifier.trdizinid180634
dc.identifier.urihttps://doi.org/10.5152/akd.2014.5189
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/180634
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24170
dc.identifier.volume15
dc.identifier.wosWOS:000351710500014
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Soc Cardiology
dc.relation.ispartofAnatolian Journal of Cardiology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectechocardiography
dc.subjectobesity
dc.subjectregression analysis
dc.subjectstrain
dc.titleEarly detection of myocardial deformation by 2D speckle tracking echocardiography in normotensive obese children and adolescents
dc.typeArticle

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