Relationship between red cell distribution width and long-term mortality in patients with non-ST elevation acute coronary syndrome

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dc.authoridTENEKECIOGLU, ERHAN/0000-0003-4376-2833
dc.contributor.authorBekler, Adem
dc.contributor.authorTenekecioglu, Erhan
dc.contributor.authorErbag, Gokhan
dc.contributor.authorTemiz, Ahmet
dc.contributor.authorAltun, Burak
dc.contributor.authorBarutcu, Ahmet
dc.contributor.authorGazi, Emine
dc.date.accessioned2025-01-27T20:34:56Z
dc.date.available2025-01-27T20:34:56Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: Red cell distribution width (RDW) has been reported to be a predictor of cardiac events in coronary artery disease (CAD). Here, we hypothesized that RDW level on admission would be predictive of adverse outcomes in non-ST elevation acute coronary syndrome (NST-ACS). Methods: In total, 202 patients with NST-ACS (159 males and 43 females) were retrospectively analyzed. The patients were divided into two groups based on the 50th percentile of admission RDW levels. A high RDW group (n=100) was defined as those patients having RDW levels of >14.0. The relationship between RDW and primary endpoint (cardiovascular death), secondary endpoints [(reinfarction, repeat target vessel revascularization-percutaneous/surgical)], and major adverse cardiac events (MACE) were assessed. The median follow-up time was 18 (13-24) months. Results: The patients in the high RDW group were older (62.9 vs. 57.5, p=0.001). Multivessel disease, low-density lipoprotein, creatinine, platelet, CK-MB, troponin I, and RDW were higher (p=0.047, p=0.003, p=0.012, p=0.012, p=0.017, p<0.001, respectively), and gender (male/female), ejection fraction, and hemoglobin levels were lower (p=0.021, p=0.04, p=0.016, respectively) in the high RDW group. Cardiovascular death and MACE were higher in the high RDW group (16% vs. 4.9%, p=0.01, 52% vs. 31.4%, p=0.003, respectively). By multiple regression analysis in 202 patients, age >= 65 and RDW > 14.0% on admission were found to be powerful independent predictors of cardiovascular mortality (OR: 4.5, 95% CI: 1.5-13.1, p=0.005, OR: 3.0, 95% CI: 1.0-8.9, p=0.039, respectively). Conclusion: A high RDW level on admission is associated with increased long-term mortality in patients with NST-ACS.
dc.identifier.doi10.5152/akd.2014.5645
dc.identifier.endpage639
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue8
dc.identifier.pmid25550178
dc.identifier.scopus2-s2.0-84988529986
dc.identifier.scopusqualityN/A
dc.identifier.startpage634
dc.identifier.trdizinid178013
dc.identifier.urihttps://doi.org/10.5152/akd.2014.5645
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/178013
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23521
dc.identifier.volume15
dc.identifier.wosWOS:000360292000009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKare Publ
dc.relation.ispartofAnatolian Journal of Cardiology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectacute coronary syndrome
dc.subjectmyocardial infarction
dc.subjectred cell distribution width
dc.titleRelationship between red cell distribution width and long-term mortality in patients with non-ST elevation acute coronary syndrome
dc.typeArticle

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