The long-term and post-prandial effects of berry consumption on endothelial dysfunction in adults: a systematic review and meta-analysis of randomised controlled trials

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dc.authoridKarav, Sercan / 0000-0003-4056-1673
dc.contributor.authorTalebi, Shokoofeh
dc.contributor.authorShirani, Mahsa
dc.contributor.authorShokri-Mashhadi, Nafiseh
dc.contributor.authorSadeghi, Omid
dc.contributor.authorKarav, Sercan
dc.contributor.authorBagherniya, Mohammad
dc.contributor.authorSahebkar, Amirhossein
dc.date.accessioned2025-05-29T02:57:45Z
dc.date.available2025-05-29T02:57:45Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThis systematic review and meta-analysis evaluated the long-term and post-prandial effects of berry consumption on endothelial dysfunction (ED) in adults. To identify relevant randomised controlled trials (RCTs), a systematic search was run and studies that examined the effects of berries consumption on ED markers were included. A total of 45 RCTs were included, focusing on markers such as flow-mediated dilation (FMD), pulse wave velocity (PWV), augmentation index (AIx), reactive hyperaemia index (RHI) and total peripheral resistance (TPR). The meta-analysis revealed that long-term berry consumption significantly increased FMD and decreased PWV. However, no significant effects were found for AIx, RHI or TPR. In post-prandial studies, berry consumption also improved FMD, but had no significant impact on PWV, AIx or RHI. Overall, berries were found to benefit endothelial function, particularly in improving FMD, though the effects on other cardiovascular markers were less consistent. Factors like trial design and berry type influenced outcomes.
dc.identifier.doi10.1080/09637486.2025.2450666
dc.identifier.endpage164
dc.identifier.issn0963-7486
dc.identifier.issn1465-3478
dc.identifier.issue2
dc.identifier.pmid39828522
dc.identifier.scopus2-s2.0-85215289498
dc.identifier.scopusqualityQ1
dc.identifier.startpage134
dc.identifier.urihttps://doi.org/10.1080/09637486.2025.2450666
dc.identifier.urihttps://hdl.handle.net/20.500.12428/30164
dc.identifier.volume76
dc.identifier.wosWOS:001399009700001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofInternational Journal of Food Sciences and Nutrition
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250529
dc.subjectBerries
dc.subjectendothelial dysfunction
dc.subjectmeta-analysis
dc.subjectrandomised clinical trial
dc.titleThe long-term and post-prandial effects of berry consumption on endothelial dysfunction in adults: a systematic review and meta-analysis of randomised controlled trials
dc.typeArticle

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