A Review on Biosensors for Quantification of MCP-1 as a Potential Biomarker in Diseases

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dc.authoridKarav, Sercan / 0000-0003-4056-1673
dc.contributor.authorBahaabadi, Zahra Jamalizadeh
dc.contributor.authorJavid-Naderi, Mohammad Javad
dc.contributor.authorKesharwani, Prashant
dc.contributor.authorKarav, Sercan
dc.contributor.authorSahebkar, Amirhossein
dc.date.accessioned2025-05-29T02:57:41Z
dc.date.available2025-05-29T02:57:41Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractMonocyte chemoattractant protein-1 (MCP-1) as a chemokine is essential for inflammation-related processes. It regulates immunological responses and cell migration, which contribute to inflammation. Many disorders are exacerbated by this chemokine, which attracts or grows other inflammatory cells, including monocytes/macrophages, at the site of infection or tissue injury. The elevated concentrations of MCP-1 are associated with the pathogenesis of many diseases, such as cancer, cardiovascular disease, kidney disease, and neuroinflammatory disease. Therefore, monitoring this inflammatory biomarker in the body has been recommended and strongly advised to make an accurate diagnosis and prognosis. Although MCP-1 is of great importance in disease processes, few biosensing approaches are specifically designed to detect this molecule. These are often electrochemical and optical techniques. Rapid and accurate diagnosis of inflammatory diseases by identifying biomarkers has had a great effect on the advancement of biosensors. Improved biosensor technology expansion prevents excessive prices and low sensitivity, enabling quick and correct diagnosis and tracking of disease processes. This review will concentrate on the biological functions of MCP-1, its significance in different disorders, and the features and applications of biosensors designed for MCP-1 detection and quantification.
dc.identifier.doi10.1111/imm.13944
dc.identifier.issn0019-2805
dc.identifier.issn1365-2567
dc.identifier.pmid40365864
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1111/imm.13944
dc.identifier.urihttps://hdl.handle.net/20.500.12428/30137
dc.identifier.wosWOS:001487547800001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofImmunology
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250529
dc.subjectbiomarker
dc.subjectbiosensor
dc.subjectCCL2
dc.subjectchemokines
dc.subjectinflammation
dc.subjectMCP-1
dc.titleA Review on Biosensors for Quantification of MCP-1 as a Potential Biomarker in Diseases
dc.typeReview

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