Nitrogen Doped Carbon-Dot Embedded Poly(lactic acid-co-glycolic acid) Composite Films for Potential Use in Food Packing Industry and Wound Dressing

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dc.authoridŞahiner, Mehtap / 0000-0001-8666-7954
dc.authoridŞahiner, Nurettin / 0000-0003-0120-530X
dc.authoridAri, Betül / 0000-0003-3557-3055
dc.contributor.authorŞahiner, Mehtap
dc.contributor.authorAri, Betül
dc.contributor.authorRam, Manoj K.
dc.contributor.authorŞahiner, Nurettin
dc.date.accessioned2025-01-27T20:54:05Z
dc.date.available2025-01-27T20:54:05Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractHere, nitrogen-doped carbon dots (N-doped CDs) were synthesized by the hydrothermal method embedded within poly(lactic acid-co-glycolic acid) ((PLGA)) films at different amounts. The N-doped CDs (or CD) that possess fluorescence properties also have antimicrobial properties against S. aureus and E. coli microorganisms, determined by the disc diffusion method with 19 +/- 2 and 18 +/- 1 mm zone diameters, respectively. The CD embedded PLGA films (CD@PLGA) with different CD contents revealed an increased fluorescence intensity with the increased amount of CD. Moreover, the antibacterial potency of 50% CD containing PLGA (50-CD@PLGA) films (by weight) against S. aureus and E. coli microorganisms was examined and the zone diameters were found to be 14 +/- 1 and 13 +/- 1 mm, respectively. In addition, CD release studies from different amounts of CD (2.5-50 by weight) containing composite films showed that 50-CD@PLGA film released 127 +/- 16 mg/g CD dots, which is 38 +/- 5% of the embedded CDs in about 12 days, suggesting their potential application in food packing and wound dressing. Moreover, all CD@PLGA films were found to be blood compatible via hemolysis and blood clotting index tests with 90% blood clotting indices regardless of their CD content.
dc.identifier.doi10.3390/jcs6090260
dc.identifier.issn2504-477X
dc.identifier.issue9
dc.identifier.scopus2-s2.0-85138712611
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/jcs6090260
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25968
dc.identifier.volume6
dc.identifier.wosWOS:000856403300001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherMdpi
dc.relation.ispartofJournal of Composites Science
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectfluorescence film composite
dc.subjectcarbon dot
dc.subjectantimicrobial film
dc.subjecthemocompatible
dc.subjectfood packing
dc.subjectwound dressing
dc.titleNitrogen Doped Carbon-Dot Embedded Poly(lactic acid-co-glycolic acid) Composite Films for Potential Use in Food Packing Industry and Wound Dressing
dc.typeArticle

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