Evaluation of Serum Creatinine Levels with Reference Change Value in Patients Receiving Colistin Treatment

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Küçük Resim

Tarih

2023

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Oxford University Press

Erişim Hakkı

info:eu-repo/semantics/openAccess
Attribution 3.0 United States

Özet

Objective In this study, we aimed to evaluate the serum creatinine (SCr) levels with the reference change value (RCV) in patients receiving colistin treatment. Methods We retrospectively recorded the SCr levels of 47 patients receiving colistin treatment before treatment and on days 3 and 7 after treatment. RCV was calculated with the asymmetrical RCV formula (Z = 1.64, P < .05). Percent (%) increase in the SCr results of the patients was compared with RCV and values exceeding RCV were regarded as statistically significant. Results The RCV was calculated as 15.6% for SCr. Compared with pretreatment values, SCr value on day 3 was 32/47 and on day 7 it was 36/47; as these results exceeded RCV, they were considered statistically significant. Conclusion Use of RCV in the interpretation of results between serial measurements will provide a more rapid and sensitive method when making decisions.

Açıklama

Anahtar Kelimeler

Biological variation, Colistin, Adverse effects, Toxicity, Clinical chemistry, Reference values

Kaynak

Laboratory Medicine

WoS Q Değeri

Q4

Scopus Q Değeri

Cilt

Sayı

Künye

Çinpolat, H.Y., Alkan, S., Altınışık, H.B., Ülker Çakır, D., & Oğuzman, H. (2023). Evaluation of Serum Creatinine Levels with Reference Change Value in Patients Receiving Colistin Treatment. Labmedicine. https://doi.org/10.1093/labmed/lmad009 ‌