Chromogenic sensing, biological, and optical properties of Schiff bases of 2-amino-6-methoxybenzothiazole
Yükleniyor...
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier B.V.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, a new series of Schiff base benzothiazole derivatives were synthesized and their structures were characterized by elemental analysis, FTIR, UV–VIS and NMR spectroscopy. The biological, sensory and photophysical properties of the benzothiazole derivatives were investigated. The sensing properties of the compounds were investigated UV–VIS spectroscopically, calorimetrically and theoretically. All compounds showed colorimetric, fluorometric and spectroscopic sensor properties for F−, CN−, AcO−, H2PO4− and OH− anions. Furthermore, DNA binding, DNA cleavage and antioxidant activities of compounds 1-4 were investigated. All compounds affected pBR322 DNA both hydrolytically and oxidatively, interacted with DNA in electrostatic mode, and also compounds 1 and 2 exhibited antioxidant activity close to standard BHT. In addition, the effects of electron donating and accepting substituents on the emission properties and charge transfer dynamics were investigated by fluorescence and femtosecond transient absorption spectroscopy measurements, respectively. According to fluorescence measurements, compounds 3 and 4 showed emission signal, while compounds 1 and 2 showed fluorescence quenching and weaker emission signal.
Açıklama
Anahtar Kelimeler
Benzothiazole, Biological activity, Chromogenic sensing, DFT, Femtosecond transient absorption spectroscopy, Schiff base
Kaynak
Journal of Molecular Structure
WoS Q Değeri
Q2
Scopus Q Değeri
Cilt
1295
Sayı
Künye
Akhüseyin Yıldız, E., Pepe, Y., Erdener, D., Karatay, A., Boyacioglu, B., Ünver, H., ...Elmalı, A. (2024) Chromogenic sensing, biological, and optical properties of Schiff bases of 2-amino-6-methoxybenzothiazole. Journal of Molecular Structure, 1295. doi: 10.1016/j.molstruc.2023.136731
