A comparison of the generation of free radicals in saliva of active and passive smokers

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dc.contributor.authorDemirtas, Murat
dc.contributor.authorSenel, Unal
dc.contributor.authorYuksel, Sevda
dc.contributor.authorYuksel, Mustafa
dc.date.accessioned2025-01-27T20:29:10Z
dc.date.available2025-01-27T20:29:10Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim: To reveal any correlation between cigarette smoke and malondialdehyde (MDA) values in the saliva fluid of subjects who are active smokers or nonsmoking subjects who are exposed to cigarette smoke in their environments. Materials and methods: Saliva samples were taken from 3 groups: a control group (group 1), a group inhaling smoke passively (group 2), and a test group (group 3) smoking 20 cigarettes per day; each group consisted of 20 members, giving a total sample of 60 people, aged 20 to 45 years. MDA, which is an indicator of lipid peroxidation, was measured via the colorimetric method. Results: Salivary MDA levels in smokers were found to be significantly higher compared to the control group and the group of passive smokers (P < 0.05). When compared with the control group, the MDA levels of passive smokers and active smokers were higher; when passive and active smokers were compared, the MDA levels of active smokers were higher. When all 3 groups were compared, the MDA levels in the control group (nonsmokers) were observed to be lower than the MDA level of the other 2 groups. Conclusion: It was observed that lipid peroxidation, which is an indicator used to determine oxidative stress, and MDA level, which is a product of this reactive chain, are significantly higher in individuals who are smokers. Such a high level of MDA in passive smokers indicates that smoking also affects nonsmokers negatively.
dc.identifier.doi10.3906/sag-1203-72
dc.identifier.endpage211
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue2
dc.identifier.pmid25536726
dc.identifier.scopus2-s2.0-84892385176
dc.identifier.scopusqualityQ1
dc.identifier.startpage208
dc.identifier.trdizinid213046
dc.identifier.urihttps://doi.org/10.3906/sag-1203-72
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/213046
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22850
dc.identifier.volume44
dc.identifier.wosWOS:000329790100007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTubitak Scientific & Technological Research Council Turkey
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectFree radical
dc.subjectmalondialdehyde
dc.subjectsaliva
dc.subjectcigarette
dc.subjectpassive smoking
dc.subjectthiobarbituric acid
dc.titleA comparison of the generation of free radicals in saliva of active and passive smokers
dc.typeArticle

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