An Enzymatic Glucose Biosensor Based on a Pencil Graphite Electrode Modified with Naphthalenedimide/3,4-Ethylenedioxythiophene Conjugated Polymer and Enriched with Au Nanoparticles

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dc.authoridTAN, Burcu/0000-0003-4661-9661
dc.contributor.authorTan, Burcu
dc.contributor.authorBaycan, Fatma
dc.date.accessioned2025-01-27T20:49:38Z
dc.date.available2025-01-27T20:49:38Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractN,N '-bis(2-hexyl)-2,6-(3,4 ethylenedioxythiophene)-1,4,5,8-naphthalenimide (ENDI) monomer was electropolymerized on pencil graphite electrode (PGE) and used as a biosensor for glucose immobilization for the first time. After electropolymerization of ENDI monomer on PGE (AuNPs/PENDI/PGE), the intensity of the current signal was improved by using gold nanoparticles (AuNPs). The immobilization of the glucose oxidase (GOx) enzyme was carried out by using the cross-linking reagent glutaraldehyde (GA) due to the strong pi-pi* interaction of the poly- N,N '-bis(2-hexyl)-2,6-(3,4 ethylenedioxythiophene)-1,4,5,8-naphthalenimide (PENDI) polymer. GOx/AuNPs/PENDI/PGE designed biosensor, was characterized by a wide linear glucose determination range between 0.0009-0.33 mM with a limit of detection of 0.0407 mM and a sensitivity of 0.172 mu A/mMcm(2). Herein we have shown that GOx/AuNPs/PENDI/PGE biosensor effectively provides the enzyme immobilization and very effective for glucose determination in commercial samples.
dc.identifier.doi10.1002/slct.202103437
dc.identifier.issn2365-6549
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85123731803
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1002/slct.202103437
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25258
dc.identifier.volume7
dc.identifier.wosWOS:000753970000025
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWiley-V C H Verlag Gmbh
dc.relation.ispartofChemistryselect
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectglucose biosensor
dc.subjectpencil graphite electrode graphite
dc.subjectelectropolymerization
dc.subjectnaphthalenedimide-3,4-Ethylenedioxythiophene
dc.subjectgold nanoparticles
dc.titleAn Enzymatic Glucose Biosensor Based on a Pencil Graphite Electrode Modified with Naphthalenedimide/3,4-Ethylenedioxythiophene Conjugated Polymer and Enriched with Au Nanoparticles
dc.typeArticle

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