An Enzymatic Glucose Biosensor Based on a Pencil Graphite Electrode Modified with Naphthalenedimide/3,4-Ethylenedioxythiophene Conjugated Polymer and Enriched with Au Nanoparticles
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Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley-V C H Verlag Gmbh
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
N,N '-bis(2-hexyl)-2,6-(3,4 ethylenedioxythiophene)-1,4,5,8-naphthalenimide (ENDI) monomer was electropolymerized on pencil graphite electrode (PGE) and used as a biosensor for glucose immobilization for the first time. After electropolymerization of ENDI monomer on PGE (AuNPs/PENDI/PGE), the intensity of the current signal was improved by using gold nanoparticles (AuNPs). The immobilization of the glucose oxidase (GOx) enzyme was carried out by using the cross-linking reagent glutaraldehyde (GA) due to the strong pi-pi* interaction of the poly- N,N '-bis(2-hexyl)-2,6-(3,4 ethylenedioxythiophene)-1,4,5,8-naphthalenimide (PENDI) polymer. GOx/AuNPs/PENDI/PGE designed biosensor, was characterized by a wide linear glucose determination range between 0.0009-0.33 mM with a limit of detection of 0.0407 mM and a sensitivity of 0.172 mu A/mMcm(2). Herein we have shown that GOx/AuNPs/PENDI/PGE biosensor effectively provides the enzyme immobilization and very effective for glucose determination in commercial samples.
Açıklama
Anahtar Kelimeler
glucose biosensor, pencil graphite electrode graphite, electropolymerization, naphthalenedimide-3,4-Ethylenedioxythiophene, gold nanoparticles
Kaynak
Chemistryselect
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
7
Sayı
2
