A hydrazine-bridged dinuclear ruthenium complex: Structural properties and biological activity

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dc.authoridDERVISOGLU, Gokhan/0000-0001-7195-2031
dc.authoridOzdemir, Namik/0000-0003-3371-9874
dc.contributor.authorErdener, Digdem
dc.contributor.authorDervisoglu, Gokhan
dc.contributor.authorOzdemir, Fethi Ahmet
dc.contributor.authorSerbetci, Zafer
dc.contributor.authorOzdemir, Namik
dc.contributor.authorDayan, Osman
dc.date.accessioned2025-01-27T20:24:22Z
dc.date.available2025-01-27T20:24:22Z
dc.date.issued2023
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIn this study, a new dimeric Ru(II) complex, [Ru(eta(6)-p-cymene)Cl-2](2) (mu(2)-N-2 H-4) (C1), readily synthesized with a reaction of hydrazine hydrate as ligand and [RuCl2(p-cymene)](2) dimmer in dichloromethane. The C1 complex was characterized structurally using IR, NMR, thermal gravimetry and single-crystal X-ray diffraction and theoretically using DFT techniques. Additionally, electrochemical, and optical properties were investigated in cyclic voltammetry and UV-visible spectroscopy. Furthermore, the C1 complex exhibited great antibacterial activity towards 16 Gram + and Gram - species and cell cytotoxicity towards human SH-SY5Y neuroblastoma cell, DU-145 prostate cancer cell, and A549 lung cancer cell lines. (c) 2022 Elsevier B.V. All rights reserved.
dc.description.sponsorshipScientific Research Projects Unit of Ondokuz Mayis University [PYO.FEN.1906.19.001]
dc.description.sponsorshipThis study was supported by the Scientific Research Projects Unit of Ondokuz Mayis University (Project No: PYO.FEN.1906.19.001).
dc.identifier.doi10.1016/j.molstruc.2022.134228
dc.identifier.issn0022-2860
dc.identifier.issn1872-8014
dc.identifier.scopus2-s2.0-85139189354
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.molstruc.2022.134228
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22182
dc.identifier.volume1272
dc.identifier.wosWOS:000899187400007
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofJournal of Molecular Structure
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectDinuclear Ru(II) complexes
dc.subjectHydrazine ligand
dc.subjectCytotoxicity Antibacterial activity
dc.titleA hydrazine-bridged dinuclear ruthenium complex: Structural properties and biological activity
dc.typeArticle

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