A hydrazine-bridged dinuclear ruthenium complex: Structural properties and biological activity
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Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, a new dimeric Ru(II) complex, [Ru(eta(6)-p-cymene)Cl-2](2) (mu(2)-N-2 H-4) (C1), readily synthesized with a reaction of hydrazine hydrate as ligand and [RuCl2(p-cymene)](2) dimmer in dichloromethane. The C1 complex was characterized structurally using IR, NMR, thermal gravimetry and single-crystal X-ray diffraction and theoretically using DFT techniques. Additionally, electrochemical, and optical properties were investigated in cyclic voltammetry and UV-visible spectroscopy. Furthermore, the C1 complex exhibited great antibacterial activity towards 16 Gram + and Gram - species and cell cytotoxicity towards human SH-SY5Y neuroblastoma cell, DU-145 prostate cancer cell, and A549 lung cancer cell lines. (c) 2022 Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Dinuclear Ru(II) complexes, Hydrazine ligand, Cytotoxicity Antibacterial activity
Kaynak
Journal of Molecular Structure
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
1272
