Evaluation of In-vitro Anticandidal Activity of 99 Different Commercial Plant Extract, Fixed and Essential Oils against Vaginal Candida albicans Isolates

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dc.authoridOZCAN ATES, Gulcin/0000-0002-8467-2378
dc.contributor.authorAtes, Gulcin Ozcan
dc.contributor.authorKanbur, Savas
dc.date.accessioned2025-01-27T21:01:36Z
dc.date.available2025-01-27T21:01:36Z
dc.date.issued2023
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPlant extracts (PE), fixed oils (FO) and essential oils (EO) are used in traditional medicine to treat various diseases. This study evaluated the anticandidal activity of 100 different commercially available PEs, FOs, and EOs against 19 Candida albicans vaginal isolates and C. albicans ATCC 10231. It was determined that 20 EOs and FOs had anticandidal activity. Piper nigrum FO, pine turpentine EO, pine tar EO, and Eugenia caryophyllata EO showed the highest anticandidal activity. The minimum inhibitory concentrations ( MIC) and minimum fungicidal concentrations (MFC) values of these FO and EOs were between 0.125 and 2 mu L mL(-1). The volatile components of these FOs and EOs were determined by GC-MS analysis. There were six components in E. caryophyllata EO, 38 in Pine turpentine EO, 39 in P. nigrum FO, and 119 in Pine tar EO. In conclusion, this FOs and EOs can be used to treat vulvovaginal candidiasis.
dc.description.sponsorshipCanakkale Onsekiz Mart University Scientific Research Projects Coordination Unit [THD-2020-3490]
dc.description.sponsorshipThis study was supported by Canakkale Onsekiz Mart University Scientific Research Projects Coordination Unit. Project No: THD-2020-3490. This study was conducted in Canakkale Onsekiz Mart University Experimental Research Center (COMUDAM) and Canakkale Onsekiz Mart University, Faculty of Medicine, Medical Microbiology Laboratory. We are grateful to Prof. Dr. Muserref OTKUN for Medical Microbiology Laboratory use.
dc.identifier.doi10.18016/ksutarimdoga.vi.1211862
dc.identifier.endpage1047
dc.identifier.issn2619-9149
dc.identifier.issue5
dc.identifier.startpage1034
dc.identifier.trdizinid1201621
dc.identifier.urihttps://doi.org/10.18016/ksutarimdoga.vi.1211862
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1201621
dc.identifier.urihttps://hdl.handle.net/20.500.12428/27116
dc.identifier.volume26
dc.identifier.wosWOS:001153474800009
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherKahramanmaras Sutcu Imam Univ Rektorlugu
dc.relation.ispartofKsu Tarim Ve Doga Dergisi-Ksu Journal of Agriculture and Nature
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectAnticandidal activity
dc.subjectPlant fixed oil
dc.subjectEssential oil
dc.subjectVaginal Candida
dc.titleEvaluation of In-vitro Anticandidal Activity of 99 Different Commercial Plant Extract, Fixed and Essential Oils against Vaginal Candida albicans Isolates
dc.typeArticle

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