Synthesis of tertiary propargylic phosphonates by addition of trialkynylaluminum reagents to acyl phosphonates and investigation of their antimicrobial activities

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dc.authoridYamac, Mustafa/0000-0002-7262-0036
dc.contributor.authorHossain, Mohammad Shakhawoat
dc.contributor.authorCakir, Sidika Polat
dc.contributor.authorKaraduman, Ayse Betul
dc.contributor.authorYamac, Mustafa
dc.contributor.authorDemir, Ayhan Sitki
dc.date.accessioned2025-01-27T20:35:16Z
dc.date.available2025-01-27T20:35:16Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractA series of propargylic alcohols containing phosphonates was synthesized by addition reactions of tris-(propynyl) and tris-(phenylethynyl) aluminum reagents to acyl phosphonates in good yields. Aromatic moieties of the acyl phosphonates with electron-withdrawing groups generally resulted in better isolated chemical yield. Selected propargylic phosphonates were tested for antimicrobial activities. Compounds 3a and 3h showed noticeable antifungal activity, especially against molds.
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK); Turkish Academy of Sciences (TUBA); Middle East Technical University (METU)
dc.description.sponsorshipFinancial support from the Scientific and Technological Research Council of Turkey (TUBITAK), Turkish Academy of Sciences (TUBA), and Middle East Technical University (METU) is appreciatively acknowledged. Helpful suggestions from Prof. Dr. Ozdemir Dogan are appreciated.
dc.identifier.doi10.3906/kim-1402-6
dc.identifier.endpage893
dc.identifier.issn1300-0527
dc.identifier.issue5
dc.identifier.scopus2-s2.0-84907220624
dc.identifier.scopusqualityQ3
dc.identifier.startpage880
dc.identifier.trdizinid163485
dc.identifier.urihttps://doi.org/10.3906/kim-1402-6
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/163485
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23616
dc.identifier.volume38
dc.identifier.wosWOS:000340769100019
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherTubitak Scientific & Technological Research Council Turkey
dc.relation.ispartofTurkish Journal of Chemistry
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectAcyl phosphonates
dc.subjectalkynyl organoaluminum
dc.subjectpropargylic alcohols
dc.subjecttris-(phenylethynyl)aluminum
dc.subjecttris-(propynyl)aluminum
dc.subjectantimicrobial activity
dc.titleSynthesis of tertiary propargylic phosphonates by addition of trialkynylaluminum reagents to acyl phosphonates and investigation of their antimicrobial activities
dc.typeArticle

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