Nocturnal blood pressure dipping is similar in rheumatoid arthritis patients as compared to anormal population

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dc.authoridHuseyinoglu Aydin, Ayse/0000-0002-3056-9981
dc.authoridAYDIN, Fatih/0000-0002-1017-1917
dc.authoridGonullu, Emel/0000-0002-6990-4206
dc.authoridTURGAY YILDIRIM, OZGE/0000-0002-6731-4958
dc.contributor.authorYildirim, O. Turgay
dc.contributor.authorGonullu, E.
dc.contributor.authorAydin, F.
dc.contributor.authorAksit, E.
dc.contributor.authorAydin, A. Huseyinoglu
dc.contributor.authorDagtekin, E.
dc.date.accessioned2025-01-27T20:20:08Z
dc.date.available2025-01-27T20:20:08Z
dc.date.issued2019
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjectiveRheumatoid arthritis (RA) is asystemic autoimmune inflammatory disorder which further doubles the risk of developing cardiovascular disease. Some studies suggest that in RA patients, the prevalence of hypertension increases due to prednisolone use, clinical status, genetic factors, and physical inactivity. On the other hand, dipper and non-dipper status in RA patients compared to non-RA subjects has not been investigated to our knowledge. Purpose of the study is to investigate whether non-dipper status is more deteriorated in RA patients.MethodsSixty-five RA patients and 61age-sex-matched control patients were evaluated in this cross-sectional study. Patients were classified according to 24-h ambulatory blood pressure monitoring results. Patients with previous hypertension diagnosis, coronary artery disease, and abnormal kidney function were excluded.ResultsMean age of the study sample was 53.712.3years and 40.5% were male. There was no significant difference between groups in terms of basic demographic characteristics. Leukocyte counts (p=0.001), neutrophil counts (p=0.001), and red cell distribution width (p=0.000) were significantly higher in the RA group. ABPM results indicate no significant difference between RA patients and the control group in terms of daytime systolic and diastolic blood pressure, nighttime systolic and diastolic blood pressure, and average systolic and diastolic blood pressure results (p>0.05). There was no statistical difference regarding the non-dipper status of patient groups (p=0.412). Nocturnal blood pressure dipping was significantly similar between groups (p=0.980).ConclusionIn conclusion, RA patients have similar values in terms of nocturnal blood pressure dipping and hypertension diagnosis as compared to normal population.
dc.identifier.doi10.1007/s00393-018-0451-4
dc.identifier.endpage194
dc.identifier.issn0340-1855
dc.identifier.issn1435-1250
dc.identifier.issue2
dc.identifier.pmid29651574
dc.identifier.scopus2-s2.0-85045283743
dc.identifier.scopusqualityQ3
dc.identifier.startpage190
dc.identifier.urihttps://doi.org/10.1007/s00393-018-0451-4
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21582
dc.identifier.volume78
dc.identifier.wosWOS:000460679600012
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer Heidelberg
dc.relation.ispartofZeitschrift Fur Rheumatologie
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectRheumatoid arthritis
dc.subjectHypertension
dc.subjectNocturnal fall in blood pressure
dc.subjectNocturnal hypertension
dc.subjectAmbulatory blood pressure monitoring
dc.titleNocturnal blood pressure dipping is similar in rheumatoid arthritis patients as compared to anormal population
dc.title.alternativeÄhnlicher nächtlicher Blutdruckabfall bei Patienten mit rheumatoider Arthritis wie in der Normalbevölkerung
dc.typeArticle

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