Nocturnal blood pressure dipping is similar in rheumatoid arthritis patients as compared to anormal population

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Tarih

2019

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Springer Heidelberg

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

ObjectiveRheumatoid arthritis (RA) is asystemic autoimmune inflammatory disorder which further doubles the risk of developing cardiovascular disease. Some studies suggest that in RA patients, the prevalence of hypertension increases due to prednisolone use, clinical status, genetic factors, and physical inactivity. On the other hand, dipper and non-dipper status in RA patients compared to non-RA subjects has not been investigated to our knowledge. Purpose of the study is to investigate whether non-dipper status is more deteriorated in RA patients.MethodsSixty-five RA patients and 61age-sex-matched control patients were evaluated in this cross-sectional study. Patients were classified according to 24-h ambulatory blood pressure monitoring results. Patients with previous hypertension diagnosis, coronary artery disease, and abnormal kidney function were excluded.ResultsMean age of the study sample was 53.712.3years and 40.5% were male. There was no significant difference between groups in terms of basic demographic characteristics. Leukocyte counts (p=0.001), neutrophil counts (p=0.001), and red cell distribution width (p=0.000) were significantly higher in the RA group. ABPM results indicate no significant difference between RA patients and the control group in terms of daytime systolic and diastolic blood pressure, nighttime systolic and diastolic blood pressure, and average systolic and diastolic blood pressure results (p>0.05). There was no statistical difference regarding the non-dipper status of patient groups (p=0.412). Nocturnal blood pressure dipping was significantly similar between groups (p=0.980).ConclusionIn conclusion, RA patients have similar values in terms of nocturnal blood pressure dipping and hypertension diagnosis as compared to normal population.

Açıklama

Anahtar Kelimeler

Rheumatoid arthritis, Hypertension, Nocturnal fall in blood pressure, Nocturnal hypertension, Ambulatory blood pressure monitoring

Kaynak

Zeitschrift Fur Rheumatologie

WoS Q Değeri

Q4

Scopus Q Değeri

Q3

Cilt

78

Sayı

2

Künye