Gold Nanoparticles in Nanomedicine: Unique Properties and Therapeutic Potential

Basit Öğe Kaydı
dc.authoridbechelany, mikhael/0000-0002-2913-2846
dc.contributor.authorEker, Furkan
dc.contributor.authorAkdasci, Emir
dc.contributor.authorDuman, Hatice
dc.contributor.authorBechelany, Mikhael
dc.contributor.authorKarav, Sercan
dc.date.accessioned2025-01-27T21:01:29Z
dc.date.available2025-01-27T21:01:29Z
dc.date.issued2024
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractGold nanoparticles (NPs) have demonstrated significance in several important fields, including drug delivery and anticancer research, due to their unique properties. Gold NPs possess significant optical characteristics that enhance their application in biosensor development for diagnosis, in photothermal and photodynamic therapies for anticancer treatment, and in targeted drug delivery and bioimaging. The broad surface modification possibilities of gold NPs have been utilized in the delivery of various molecules, including nucleic acids, drugs, and proteins. Moreover, gold NPs possess strong localized surface plasmon resonance (LSPR) properties, facilitating their use in surface-enhanced Raman scattering for precise and efficient biomolecule detection. These optical properties are extensively utilized in anticancer research. Both photothermal and photodynamic therapies show significant results in anticancer treatments using gold NPs. Additionally, the properties of gold NPs demonstrate potential in other biological areas, particularly in antimicrobial activity. In addition to delivering antigens, peptides, and antibiotics to enhance antimicrobial activity, gold NPs can penetrate cell membranes and induce apoptosis through various intracellular mechanisms. Among other types of metal NPs, gold NPs show more tolerable toxicity capacity, supporting their application in wide-ranging areas. Gold NPs hold a special position in nanomaterial research, offering limited toxicity and unique properties. This review aims to address recently highlighted applications and the current status of gold NP research and to discuss their future in nanomedicine.
dc.identifier.doi10.3390/nano14221854
dc.identifier.issn2079-4991
dc.identifier.issue22
dc.identifier.pmid39591094
dc.identifier.scopus2-s2.0-85210424190
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/nano14221854
dc.identifier.urihttps://hdl.handle.net/20.500.12428/27058
dc.identifier.volume14
dc.identifier.wosWOS:001365877400001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMdpi
dc.relation.ispartofNanomaterials
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectgold nanoparticle
dc.subjectdrug delivery
dc.subjectbioimaging
dc.subjectbiosensor
dc.subjectantibacterial
dc.subjectphotothermal therapy
dc.subjectphotodynamic therapy
dc.subjectanticancer
dc.subjectLSPR
dc.subjectSERS
dc.titleGold Nanoparticles in Nanomedicine: Unique Properties and Therapeutic Potential
dc.typeReview Article

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu