Role of milk glycome in prevention, treatment, and recovery of COVID-19

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dc.authoridSAHUTOGLU, Arif Sercan/0000-0003-1183-3553
dc.authoridKaplan, Merve/0000-0002-3322-0988
dc.authoridKARAV, SERCAN/0000-0003-4056-1673
dc.authoridSaritas, Sumeyye/0009-0003-4485-3208
dc.contributor.authorKaplan, Merve
dc.contributor.authorSahutoglu, Arif Sercan
dc.contributor.authorSaritas, Sumeyye
dc.contributor.authorDuman, Hatice
dc.contributor.authorArslan, Aysenur
dc.contributor.authorPekdemir, Burcu
dc.contributor.authorKarav, Sercan
dc.date.accessioned2025-01-27T20:16:32Z
dc.date.available2025-01-27T20:16:32Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractMilk contains all essential macro and micro-nutrients for the development of the newborn. Its high therapeutic and antimicrobial content provides an important function for the prevention, treatment, and recovery of certain diseases throughout life. The bioactive components found in milk are mostly decorated with glycans, which provide proper formation and modulate the biological functions of glycosylated compounds. The glycome of milk consists of free glycans, glycolipids, and N- and O- glycosylated proteins. Recent studies have shown that both free glycans and glycan-containing molecules have antiviral characteristics based on different mechanisms such as signaling, microbiome modulation, natural decoy strategy, and immunomodulatory action. In this review, we discuss the recent clinical studies and potential mechanisms of free and conjugated glycans' role in the prevention, treatment, and recovery of COVID-19.
dc.identifier.doi10.3389/fnut.2022.1033779
dc.identifier.issn2296-861X
dc.identifier.pmid36424926
dc.identifier.scopus2-s2.0-85142344782
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.3389/fnut.2022.1033779
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21275
dc.identifier.volume9
dc.identifier.wosWOS:000889783100001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherFrontiers Media Sa
dc.relation.ispartofFrontiers in Nutrition
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectglycosylation
dc.subjecthuman milk oligosaccharides
dc.subjectglycans
dc.subjectwhey protein
dc.subjectCOVID-19
dc.subjectSARS-CoV-2
dc.subjectantiviral activity
dc.titleRole of milk glycome in prevention, treatment, and recovery of COVID-19
dc.typeReview Article

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