BIOCHEMICAL COMPOSITION, AND IN VITRO ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES OF SALVIA FRUTICOSA, AN ETHNOMEDICINAL PLANT

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dc.authoridŞimşek, Özcan / 0000-0002-3210-7641
dc.contributor.authorBozyel, M. E.
dc.contributor.authorCanlı, K.
dc.contributor.authorBenek, A.
dc.contributor.authorŞimşek, Özcan
dc.contributor.authorAkata, I.
dc.contributor.authorAltuner, E. M.
dc.date.accessioned2025-01-27T20:16:34Z
dc.date.available2025-01-27T20:16:34Z
dc.date.issued2023
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractSalvia fruticosa (Anatolian sage) is a medicinal plant with a natural distribution in the Central and Eastern Mediterranean. It has ethnomedicinal uses in traditional medicine. The aim of this study was to investigate the biochemical composition and in vitro antimicrobial and antioxidant activities of S. fruticosa. The in vitro antimicrobial activity of S. fruticosa ethanol extract (SFEt) by disk diffusion method against thirty-nine bacterial (including eleven multidrug-resistant strains) and two fungal strains was examined. The determination of antioxidant activity was carried out by the DPPH method. The identification of biochemical composition was by GC-MS. Twenty-three components were identified in SFEt and the main one was D-camphor (20.27%). SFEt has antimicrobial activity against a wide range of microorganisms tested. The highest activity has been demonstrated against Staphylococcus epidermidis DSMZ 20044 (ST12) as a Gram-positive bacteria with a 21 mm zone of inhibition and Proteus vulgaris (MDR6) as a Gram-negative bacteria with a 13 mm zone of inhibition. Also, the data from Streptococcus pneumonia (MDR7) was very striking because a higher activity has been observed than fourteen positive controls. SFEt showed antioxidant activity almost as high as Ascorbic acid. These results have shown that S. fruticosa has a high antimicrobial and antioxidant potential.
dc.description.sponsorshipDokuz Eyluuml;l University Scientific Research Coordination Unit [2019, KB.FEN.014]
dc.description.sponsorshipAcknowledgements. The authors acknowledge the Dokuz Eylul University Scientific Research Coordination Unit for funding this research (project number: 2019.KB.FEN.014) .
dc.identifier.doi10.15666/aeer/2104_32433256
dc.identifier.endpage3256
dc.identifier.issn1589-1623
dc.identifier.issn1785-0037
dc.identifier.issue4
dc.identifier.scopus2-s2.0-85166571657
dc.identifier.scopusqualityQ3
dc.identifier.startpage3243
dc.identifier.urihttps://doi.org/10.15666/aeer/2104_32433256
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21297
dc.identifier.volume21
dc.identifier.wosWOS:001042610300001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAloki Applied Ecological Research And Forensic Inst Ltd
dc.relation.ispartofApplied Ecology and Environmental Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectSalvia fruticosa
dc.subjectAnatolian sage
dc.subjectGC-MS
dc.subjectdisk diffusion
dc.subjectDPPH
dc.subjectmultidrug-resistant bacteria
dc.titleBIOCHEMICAL COMPOSITION, AND IN VITRO ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES OF SALVIA FRUTICOSA, AN ETHNOMEDICINAL PLANT
dc.typeArticle

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