The effects of carbogen and hyperbaric oxygen treatment on fracture healing in rats

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dc.authoridYilmaz, Onur/0000-0001-7515-0300
dc.authoridTISKAOGLU, Ramazan/0000-0002-6282-8378
dc.authoridkaymaz, burak/0000-0001-6207-8063
dc.contributor.authorMenendi, Umman
dc.contributor.authorNusran, Gurdal
dc.contributor.authorKaymaz, Burak
dc.contributor.authorTiskaoglu, Ramazan
dc.contributor.authorYilmaz, Onur
dc.contributor.authorGoret, Ceren Canbey
dc.date.accessioned2025-01-27T20:25:07Z
dc.date.available2025-01-27T20:25:07Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBACKGROUND: Bone fractures and fracture healing are one of the most common problems among orthopedic surgeons. In this study, we investigated the effects of hyperbaric oxygen (HBO) and carbogen (C) treatment on fracture healing in the experimental animal model. METHODS: Twenty-four male Wistar-Albino rats were randomly divided into three groups as Group 1 (C inhalation therapy), Group 2 (HBO inhalation therapy), and Group 3 (control group), with eight rats in each group. HBO and C treatment were given to the rats in Group 1 and Group 2 1 week before the surgical procedure and 3 weeks after the surgical procedure. Following the surgical procedure, all rats were killed at the end of the 3rd week and the healing tissue in the fracture line was evaluated clinically, radiologically, and histopathologically. RESULTS: Although there were higher histopathological, radiological, and clinical scores in the HBO and C groups in terms of fracture healing compared to the control group, there was no statistically significant difference between the groups. CONCLUSION: There are many studies in the literature that examine the systemic and local effects of HBO and C treatments and show that they increase tissue oxygenation. Our study showed that HBO and C groups had no beneficial or harmful effects on fracture healing compared to the control group.
dc.identifier.doi10.14744/tjtes.2021.02575
dc.identifier.endpage417
dc.identifier.issn1306-696X
dc.identifier.issn1307-7945
dc.identifier.issue4
dc.identifier.pmid35485502
dc.identifier.scopus2-s2.0-85129779646
dc.identifier.scopusqualityQ3
dc.identifier.startpage411
dc.identifier.trdizinid1169006
dc.identifier.urihttps://doi.org/10.14744/tjtes.2021.02575
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1169006
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22439
dc.identifier.volume28
dc.identifier.wosWOS:000781192000002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Assoc Trauma Emergency Surgery
dc.relation.ispartofUlusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectCarbogen
dc.subjectfracture healing
dc.subjecthyperbaric oxygen
dc.titleThe effects of carbogen and hyperbaric oxygen treatment on fracture healing in rats
dc.title.alternativeSıçanlarda karbojen ve hiperbarik oksijen tedavisinin kırık iyileşmesine etkileri
dc.typeArticle

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