Silver Nanoparticles in Therapeutics and Beyond: A Review of Mechanism Insights and Applications

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dc.authoridWitkowska, Anna/0000-0002-0092-3409
dc.authoridAkdasci, Emir/0009-0009-5996-6567
dc.authoridEker, Furkan/0009-0002-5260-6111
dc.authoridbechelany, mikhael/0000-0002-2913-2846
dc.contributor.authorEker, Furkan
dc.contributor.authorDuman, Hatice
dc.contributor.authorAkdasci, Emir
dc.contributor.authorWitkowska, Anna Maria
dc.contributor.authorBechelany, Mikhael
dc.contributor.authorKarav, Sercan
dc.date.accessioned2025-01-27T20:34:40Z
dc.date.available2025-01-27T20:34:40Z
dc.date.issued2024
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractSilver nanoparticles (NPs) have become highly promising agents in the field of biomedical science, offering wide therapeutic potential due to their unique physicochemical properties. The unique characteristics of silver NPs, such as their higher surface-area-to-volume ratio, make them ideal for a variety of biological applications. They are easily processed thanks to their large surface area, strong surface plasmon resonance (SPR), stable nature, and multifunctionality. With an emphasis on the mechanisms of action, efficacy, and prospective advantages of silver NPs, this review attempts to give a thorough overview of the numerous biological applications of these particles. The utilization of silver NPs in diagnostics, such as bioimaging and biosensing, as well as their functions in therapeutic interventions such as antimicrobial therapies, cancer therapy, diabetes treatment, bone repair, and wound healing, are investigated. The underlying processes by which silver NPs exercise their effects, such as oxidative stress induction, apoptosis, and microbial cell membrane rupture, are explored. Furthermore, toxicological concerns and regulatory issues are discussed, as well as the present difficulties and restrictions related to the application of silver NPs in medicine.
dc.identifier.doi10.3390/nano14201618
dc.identifier.issn2079-4991
dc.identifier.issue20
dc.identifier.pmid39452955
dc.identifier.scopus2-s2.0-85207672297
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/nano14201618
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23410
dc.identifier.volume14
dc.identifier.wosWOS:001341723600001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMdpi
dc.relation.ispartofNanomaterials
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectsilver nanoparticles
dc.subjectbiomedical applications
dc.subjecttoxicity
dc.subjectantimicrobial and anticancer activity
dc.subjectbone healing and wound repair activity
dc.subjectbioimaging and biosensor
dc.subjectdiabetes
dc.subjectdental applications
dc.titleSilver Nanoparticles in Therapeutics and Beyond: A Review of Mechanism Insights and Applications
dc.typeReview Article

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