Synthesis of ?-chloro-?-aminophosphonate derivatives via the regioselective ring opening of unactivated aziridine-2-phosphonates
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Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A series of unactivated racemic and chiral aziridine-2-phosphonates were synthesized by modified Gabriel-Cromwell reaction. Ring opening reaction of the synthesized phosphonates by gaseous HCl provided access to a wide range of biologically interesting novel beta-chloro-alpha-aminophosphonates. All reactions toward each of the above-mentioned products can be conducted regioselectively in high yields. [GRAPHICS] .
Açıklama
Anahtar Kelimeler
Aziridine-2-phosphonates, regioselective ring opening, beta-chloro-alpha-aminophosphonates
Kaynak
Phosphorus Sulfur and Silicon and The Related Elements
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
193
Sayı
12
