Toxicity of gamma aluminium oxide nanoparticles in the Mediterranean mussel (Mytilus galloprovincialis): histopathological alterations and antioxidant responses in the gill and digestive gland
Yükleniyor...
Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor and Francis
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose: Accumulation of Gamma aluminium oxide nanoparticles c-Al2O3 NPs significant impact on
aquatic ecosystems. However, the toxicity of c-Al2O3 NPs in aquatic organisms has been limited investigated. This study investigated histopathological changes and antioxidant responses induced by different concentrations of c-Al2O3 NPs in Mytilus galloprovincialis.
Material and methods: In this study, mussels were exposed to different concentrations of 5 nm
c-Al2O3 NPs (0, 5, 20 and 40 mg/L) for 96 h under controlled laboratory conditions. Gill and digestive
gland from mussels were assessed to histopathological (light microscopy, histopathological condition
indices, digestive gland tubule types), SOD, CAT, GPx activities.
Results: Histopathological indices calculated higher, and significantly different in all exposure groups
compared to the control group in gill and digestive gland (p < 0.05). Atrophic phase tubules proportion very high in 20 and 40 mg/L c-Al2O3 NPs exposure groups. No significant changes in CAT activities in the gill and digestive gland (p > 0.05). Superoxide dismutase (SOD) activities significantly
different (p 0.05) in the digestive gland from 20 mg/L c-Al2O3 NPs exposures, and GPx activities significantly different (p < 0.05) in gill from 40 mg/L c-Al2O3 NPs exposures.
Conclusion: These results indicate that contamination of c-Al2O3 NPs negatively affects the
aquatic organism.
Açıklama
Anahtar Kelimeler
Histopathology, Oxidative stress, Gamma aluminium oxide nanoparticles, Nanotoxicity, Mediterranean mussel
Kaynak
Biomarkers
WoS Q Değeri
Q3
Scopus Q Değeri
Cilt
26
Sayı
3
Künye
Ertürk Gürkan, S., & Gürkan, M. (2021). Toxicity of gamma aluminium oxide nanoparticles in the Mediterranean mussel (Mytilus galloprovincialis): histopathological alterations and antioxidant responses in the gill and digestive gland. Biomarkers, 26(3), 248–259. https://doi.org/10.1080/1354750x.2021.1878558
