Bacteria isolated from blood cultures in a neonatal and pediatric intensive care unit and their antibiotic resistance: 5-year results

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dc.authorid0000-0003-2154-3074
dc.authorid0000-0001-7363-5056
dc.authorid0000-0001-5596-3347
dc.contributor.authorOrhan, Zerife
dc.contributor.authorKayis, Arzu
dc.contributor.authorKirisci, Ozlem
dc.contributor.authorKucuk, Burak
dc.contributor.authorAltun, Mehzat
dc.contributor.authorAral, Murat
dc.date.accessioned2026-02-03T11:59:40Z
dc.date.available2026-02-03T11:59:40Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: Bloodstream infections represent a leading cause of illness and death among children in developing nations. The aim of this study was to determine the bacterial profile and antibiotic resistance status of pathogens isolated from blood cultures taken from children in the neonatal and pediatric intensive care units of a university hospital in T & uuml;rkiye. Methods: Isolation, species identification, and antibiotic susceptibility testing of 1,197 blood culture samples from the neonatal and pediatric intensive care units of a university hospital were conducted using classical methods and automated Bact Alert and BD Phoenix systems between January 2018 and December 2022. Results: Of the 1197 blood cultures included in the study, 776 (64.82%) were isolated from neonatal, and 421 (35.18%) were isolated from the pediatric intensive care unit. Of the 1197 microorganisms identified in blood cultures, 868 (72.51%) were gram-positive, 259 (21.63%) were gram-negative bacteria, and 70 (5.84%) were fungi. Among the identified bacteria, the most common microorganism was coagulase-negative staphylococci (62.40%), followed by Klebsiella pneumoniae (6.59%) and Acinetobacter baumannii (6.26%). Methicillin resistance was 93.44% in coagulase-negative staphylococci and 54.54% in Staphylococcus aureus. Among Gram-negative bacteria, Acinetobacter baumannii showed a high resistance to all antibiotics tested, while Serratia marcescens had the highest susceptibility rate. Conclusion: According to the results of our study, the antibacterial resistance rates of microorganisms isolated from blood cultures differ. We believe that regular monitoring of susceptibility patterns of strains will encourage rational antibiotic use and provide more effective treatment by reducing resistance among bacteria.
dc.identifier.doi10.59213/TP.2025.218
dc.identifier.endpage115
dc.identifier.issn2718-0085
dc.identifier.issn2792-0429
dc.identifier.issue2
dc.identifier.scopus2-s2.0-105010135023
dc.identifier.scopusqualityQ4
dc.identifier.startpage108
dc.identifier.trdizinid1341459
dc.identifier.urihttps://doi.org/10.59213/TP.2025.218
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1341459
dc.identifier.urihttps://hdl.handle.net/20.500.12428/34358
dc.identifier.volume6
dc.identifier.wosWOS:001525468600007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherGalenos Publ House
dc.relation.ispartofTrends in Pediatrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260130
dc.subjectantibiotic resistance
dc.subjectchild
dc.subjectintensive care units
dc.subjectneonatal
dc.subjectT & uuml;rkiye
dc.titleBacteria isolated from blood cultures in a neonatal and pediatric intensive care unit and their antibiotic resistance: 5-year results
dc.typeArticle

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