The comparison of the degree of apoptosis in ovaries and fallopian tubes between two different surgical interventions for tubal ligation: A rat model

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dc.authoridMumusoglu, Sezcan/0000-0001-7000-7580
dc.contributor.authorMumusoglu, Sezcan
dc.contributor.authorHacivelioglu, Servet
dc.contributor.authorSokmensuer, Lale Karakoc
dc.contributor.authorKaratayli, Rengin
dc.contributor.authorSuzer, Aysegul
dc.contributor.authorKaymaz, Figen
dc.date.accessioned2025-01-27T20:52:17Z
dc.date.available2025-01-27T20:52:17Z
dc.date.issued2018
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: To compare the degree of apoptosis in ovaries and tubal epithelium observed secondary to tubal ligation either by Pomeroy's method or bipolar electrocauterization in a rat model. Material and Methods: A total of 24 female Sprague-Dawley rats were randomly assigned into 3 study groups: control (n=8), Pomeroy (n=8), and the electrocauterization group (n=8). Apoptotic cells were detected on the primary, secondary, tertiary follicles of the ovaries, and on the tubal epithelium using terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end-labeling. The apoptotic index was calculated for each group by the percentage of the stained cells. Results: The apoptotic index of tubal epithelium was significantly higher in the bipolar electrocauterization group compared with the control and Pomeroy groups (3.1 +/- 0.8 vs. 1.4 +/- 1.0, p=0.018 and 2.0 +/- 1.2, p=0.03, respectively) whereas there was no significant difference between Pomeroy's method and the control group. The apoptotic index of primary follicles was higher in the bipolar electrocauterization group compared with the control and Pomeroy's method groups (3.4 +/- 0.5 vs. 1.2 +/- 0.4, p<0.001 and 1.8 +/- 0.8, p=0.005, respectively), but there was no significant difference between Pomeroy's method and the control group. The apoptotic index of secondary and tertiary follicles was similar for each group. Conclusion: Pomeroy's technique, as a permanent contraception method, is associated with lower apoptotic index on ovary and fallopian tube when compared with bipolar electrocauterization.
dc.identifier.doi10.4274/jtgga.2016.0192
dc.identifier.endpage16
dc.identifier.issn1309-0399
dc.identifier.issn1309-0380
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85045200686
dc.identifier.scopusqualityQ3
dc.identifier.startpage11
dc.identifier.trdizinid385400
dc.identifier.urihttps://doi.org/10.4274/jtgga.2016.0192
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/385400
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25720
dc.identifier.volume19
dc.identifier.wosWOS:000426433200004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofJournal of The Turkish-German Gynecological Association
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectTubal ligation
dc.subjectbipolar electrocauterization
dc.subjectPomeroy
dc.subjectovarian reserve
dc.subjectfallopian tube
dc.titleThe comparison of the degree of apoptosis in ovaries and fallopian tubes between two different surgical interventions for tubal ligation: A rat model
dc.typeArticle

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