Evaluation of serum L-FABP levels in patients with acute pancreatitis

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dc.contributor.authorKocak, Erdem
dc.contributor.authorAkbal, Erdem
dc.contributor.authorKoklu, Seyfettin
dc.contributor.authorAdam, Gurhan
dc.date.accessioned2025-01-27T20:11:48Z
dc.date.available2025-01-27T20:11:48Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBACKGROUND: The aim of this study was to assess the serum L-FABP levels in patients with acute pancreatitis and compare with healthy subjects. METHODS: Thirty patients with acute pancreatitis and thirty consecutive healthy age-and sex-matched control subjects were included into the study. The serum levels of L-FABP were measured upon admission and at the remission period. RESULTS: Upon admission, serum L-FABP concentration was significantly higher in patients with acute pancreatitis compared to control subjects (41009.41 +/- 32401.31 pg/ml vs. 17057.00 +/- 5015.74 pg/ml, p=0.008). Serum L-FABP levels decreased after the remission period; however, the differences were not statistically significant. In addition, serum L-FABP levels showed significant correlation with AST and LDH levels. CONCLUSION: Increased serum L-FABP levels may be related to the mechanism of pancreatic microcirculatory disturbance in patients with acute pancreatitis, suggesting that serum L-FABP could be used for a potential biomarker of acute pancreatitis.
dc.identifier.doi10.5505/tjtes.2015.49879
dc.identifier.endpage43
dc.identifier.issn1306-696X
dc.identifier.issue1
dc.identifier.pmid25779711
dc.identifier.scopus2-s2.0-84923039171
dc.identifier.scopusqualityQ3
dc.identifier.startpage39
dc.identifier.trdizinid197920
dc.identifier.urihttps://doi.org/10.5505/tjtes.2015.49879
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/197920
dc.identifier.urihttps://hdl.handle.net/20.500.12428/20729
dc.identifier.volume21
dc.identifier.wosWOS:000351544800007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Assoc Trauma Emergency Surgery
dc.relation.ispartofUlusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectAcute pancreatitis
dc.subjectdiagnosis
dc.subjectserum L-FABP
dc.titleEvaluation of serum L-FABP levels in patients with acute pancreatitis
dc.title.alternativeAkut pankreatitli hastalarda serum L-FABP düzeylerinin değerlendirilmesi
dc.typeArticle

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